Clinical trials
Chemotherapy-induced Peripheral Neuropathy clinical trials
Below are recruiting chemotherapy-induced peripheral neuropathy clinical trials, each written for real people, not researchers. We’re tracking 68 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06724861Recruiting
Sensory rehabilitation for chemo-related nerve pain
This trial is testing a sensory rehabilitation program for people who have ongoing nerve pain or numbness in their hands or feet after chemotherapy. It aims to help improve sensation and movement.
TzrifinAges 18 years+ - NCT06706544RecruitingPhase 2/Phase 3
Ozone treatment for numbness or tingling after chemo
This trial tests whether ozone treatment (a gas therapy) can help relieve numbness or tingling caused by chemotherapy. It is for people whose cancer is stable or in remission and who have had these nerve symptoms for at least 3 months.
Las Palmas, Las PalmasAges 18 years+ - NCT06430814Recruiting
Blood test to predict nerve damage from paclitaxel
This study looks at whether certain markers in your blood can predict nerve damage from paclitaxel chemotherapy. If you join, researchers will monitor your nerve health during treatment to better understand and possibly prevent side effects.
OdenseAges 18 years+ - NCT06490159Recruiting
Predicting nerve damage from paclitaxel for stomach cancer
This study looks at whether a common chemotherapy drug called paclitaxel (Taxol) causes nerve damage (peripheral neuropathy) in people with advanced stomach cancer. The goal is to find out who is most likely to get this side effect, so doctors can better protect patients during treatment.
Kurashiki, Okayama-kenAges 20 years+ - NCT06389721Recruiting
Preventing nerve damage from breast cancer chemotherapy
This study looks at how certain chemotherapy drugs affect the brain and cause nerve damage (peripheral neuropathy) in people with breast cancer. The goal is to find ways to prevent or reduce these side effects so that treatment can be more comfortable and effective.
Houston, TexasAges 18 years+ - NCT06162403Recruiting
Nerve stimulation for chemo-related leg pain
This study tests whether a small device that sends gentle electrical pulses to nerves in your leg can relieve pain caused by chemotherapy. If you have ongoing nerve pain in your legs from past chemo, this treatment might offer a new way to manage it.
Houston, TexasAges 18–85 - NCT06139458Recruiting
Cooling therapy to prevent nerve damage from chemo
This trial tests if cooling sleeves and gloves during chemotherapy can help prevent nerve damage (peripheral neuropathy) in people with gynecologic cancers. If you are receiving a common chemo drug called paclitaxel, this approach might reduce side effects like numbness or pain in your hands and feet.
Hartford, ConnecticutAges 18 years+ - NCT04652609Recruiting
Exercise program to prevent nerve damage from chemotherapy
This trial studies an exercise program (PRESIONA) that may help prevent nerve pain or numbness caused by a common type of breast cancer chemotherapy called taxane-based treatment. It targets people with HER2-positive breast cancer who are about to start neoadjuvant chemotherapy.
GranadaAges 18–70 - NCT05840562RecruitingPhase 3
Capsaicin skin patch vs duloxetine for nerve pain after chemo
This Phase 3 trial tests whether a capsaicin patch works better than duloxetine tablets to reduce painful nerve pain after chemotherapy. It aims to help people whose “gloves and socks” nerve pain has lasted after chemo.
AngersAges 18 years+ - NCT05642611RecruitingPhase 3
Cooling and compression for nerve protection during chemotherapy
This study tests whether using cooling and/or compression on the arms or legs can prevent nerve damage that can happen from certain chemotherapy drugs. If you get eligible chemo soon, this may help lower the chance of painful numbness or tingling during treatment.
Birmingham, AlabamaAges 18 years+ - NCT05606068Recruiting
Cooling sleeve to help prevent nerve damage from paclitaxel
This trial tests a limb “cryocompression” system (a cooling and gentle pressure device) to help prevent chemotherapy-related nerve pain and numbness. It’s for people starting weekly paclitaxel, and may help those trying to avoid or reduce peripheral neuropathy.
SingaporeAges 21–80 - NCT05411523Recruiting
Spinal cord stimulation study for long-term chemotherapy nerve pain
This trial tests whether spinal cord stimulation can reduce pain and improve quality of life in people with long-lasting nerve pain from chemotherapy (CIPN). You must already have tried at least two nerve-pain medicines and still have significant pain, and you must have had a successful spinal cord stimulator test before joining.
Rochester, MinnesotaAges 18 years+ - NCT04970121RecruitingPhase 2
Duloxetine for chemotherapy nerve pain in solid tumor patients
This Phase 2 trial tests duloxetine to see if it safely reduces painful nerve damage caused by chemotherapy (especially taxanes) in people with solid tumors. If you have moderate-to-severe nerve pain and meet lab and heart-safety checks, this study may be an option.
Bengbu, AnhuiAges 18–75 - NCT04786977Recruiting
Measuring a nerve-related eye signal in children on vincristine
This study checks how children’s pupil responses look while they are receiving vincristine (a cancer medicine). The goal is to learn whether a simple eye measurement can reflect how the body is responding to treatment.
Washington D.C., District of ColumbiaAges 6–18 - NCT04763356Recruiting
Remote monitoring to manage nerve pain after chemotherapy
This study tests whether remote check-ins (via phone/app/website) can help manage chemotherapy-related nerve pain in the hands and feet. It enrolls adults who developed nerve symptoms after certain cancer medicines and need ongoing monitoring.
Salt Lake City, UtahAges 18 years+ - NCT04415892Recruiting
Studying a therapy target for nerve pain after chemotherapy
This study looks at “TRP channels,” which are part of how nerves sense pain and temperature, to understand nerve pain (neuropathy) after chemotherapy. It may help improve how future treatments prevent or reduce nerve pain in people who have had certain chemotherapy drugs.
Leuven, Vlaams-BrabantAges 18–75 - NCT04299893RecruitingPhase 2/Phase 3
Ozone treatment for chemotherapy nerve pain
This trial tests whether ozone therapy can reduce painful nerve damage caused by chemotherapy. It is for adults with ongoing moderate-to-severe pain in the hands or feet after chemotherapy.
Las Palmas de Gran Canaria, Las PalmasAges 18–100 - NCT07708233RecruitingPhase 4
Benfotiamine vs vitamin B complex for diabetic nerve pain
This study compares two types of vitamin B supplements to see which one better relieves nerve pain and numbness in people with diabetes. It may help if you have diabetic neuropathy and are looking for a safe, non-drug option.
Pathumthani, BangkokAges 18 years+ - NCT07274735Recruiting
Combined therapy for diabetic nerve pain
This study tests how well two treatments, INF and OEP, work together to help people with diabetic peripheral neuropathy, a condition that causes nerve pain in the feet and legs. It may offer a way to reduce pain and improve walking ability.
Lahore, Punjab ProvinceAges 50–75 - NCT05850130Recruiting
Acupuncture for nerve pain after colon cancer treatment
This trial tests whether acupuncture can relieve the nerve pain and tingling in the hands and feet that often occurs after treatment with oxaliplatin, a chemotherapy drug for gastrointestinal cancers. The study aims to help people manage this side effect and improve their daily comfort.
AmiensAges 18 years+
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Common questions
- Are there clinical trials for chemotherapy-induced peripheral neuropathy?
- Yes. Clin2 currently lists 68 recruiting chemotherapy-induced peripheral neuropathy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chemotherapy-induced peripheral neuropathy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chemotherapy-induced peripheral neuropathy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Peripheral Neuropathy Due to Chemotherapy
- Paclitaxel-induced Peripheral Neuropathy
- Chemotherapy Induced Pain Neuropathy
- Oxaliplatin Induced Peripheral Neuropathy in Cancer Patients
- Taxane-induced Peripheral Neuropathy
- Peripheral Neuropathy
- Diabetic Peripheral Neuropathy
- Chemotherapy-induced Nausea and Vomiting
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.