Clinical trials
Children clinical trials
Below are recruiting children clinical trials, each written for real people, not researchers. We’re tracking 3,086 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04156893RecruitingPhase 1/Phase 2
RH-matched blood transfusions for sickle cell patients
This study tests whether giving red blood cells matched to your child’s RH (a blood marker) can improve safety and fit for people with sickle cell disease who need regular transfusions. It may help reduce mismatches by using blood units selected to match the child’s blood type more closely.
Philadelphia, PennsylvaniaAges 6 months+ - NCT04629469Recruiting
Two types of MRI scans in children
This study compares two MRI scan settings (a lower and higher magnetic field) in children to see how well they work for pediatric patients. It may help doctors choose the best MRI approach for kids without changing any care beyond the scan itself.
Kansas City, MissouriAges birth–22 years - NCT04569149Recruiting
Registry for very small-bodied, low-head-growth syndromes
This is a registry (a secure list of patients) for people with rare conditions that cause very small size and a smaller-than-usual head from early life. It helps researchers learn more about these conditions and how they vary from person to person.
Wilmington, DelawareAges Any age - NCT04118712Recruiting
Ovarian tissue banking for girls and teens having ovary surgery
This study collects small pieces of ovarian tissue during certain surgeries in girls and teens (before or after puberty). The goal is to bank the tissue for possible future fertility or medical research.
Chicago, IllinoisAges Up to 18 years - NCT05805410Recruiting
Trunk therapy in children with spastic cerebral palsy
This study looks at how special trunk (core) exercises or positioning affect movement and muscle control in children with spastic cerebral palsy (CP). It may help families understand which trunk-focused interventions improve function and comfort.
Chicago, IllinoisAges 4–12 - NCT05351216Recruiting
Sirolimus safety with routine vaccines for a rare blood vessel tumor
This trial studies how the medicine sirolimus affects children’s response to routine vaccines during treatment for kaposiform hemangioendothelioma (KHE). It compares vaccinated KHE patients taking sirolimus with healthy children getting the same vaccines.
Shanghai, Shanghai MunicipalityAges Up to 12 years - NCT03758521Recruiting
Natural history study of SSADH deficiency in children and adults
This study tracks how SSADH deficiency (a genetic condition) affects health over time. There is no new drug being tested; instead, researchers collect medical history and perform certain optional scans/tests that can help describe disease patterns and future treatment needs.
Boston, MassachusettsAges Any age - NCT02851758Recruiting
Autologous mitochondria treatment for critically ill heart children on ECMO
This trial looks at giving a child their own mitochondria to help protect the heart from injury caused by reduced blood flow. It is for children with serious heart problems who are on a heart-lung machine and may have signs of ischemia (reduced blood flow damage).
Boston, MassachusettsAges Up to 17 years - NCT05319678Recruiting
Music and voice testing in cochlear implant users
This study looks at how well cochlear implant users do musical and voice skills, including children and adults who use one or two implants. You might benefit by helping researchers understand how these skills develop and how devices work over time.
Madrid, MadridAges 6 years+ - NCT02493478Recruiting
Improve safety during placing breathing tubes in children
This trial looks at ways to improve the safety and quality of emergency breathing tube placement in pediatric critical care and emergency settings. It may help reduce complications and improve how clinicians do these urgent procedures.
Birmingham, AlabamaAges Any age - NCT02543866RecruitingPhase 1
Fecal transplant to clear resistant gut bacteria in children
This Phase 1 study tests whether transferring stool microbiome (a fecal microbiota transplant) can help clear antibiotic-resistant bacteria living in the gut. It’s meant for children and teens who have had infections from these resistant bacteria and who can safely take the study’s planned treatment.
Seattle, WashingtonAges 7–21 - NCT02055105Recruiting
Study tests a blood test pattern in children with sepsis
This trial studies how a specific pattern in blood (called “molecular fingerprinting”) changes in children with suspected or developing sepsis. The goal is to help doctors better recognize sepsis early and understand how it progresses, which may improve care.
Phoenix, ArizonaAges 1–18 - NCT02539407Recruiting
Study drug levels in critically ill children
This trial measures how anti-infective medicines move through a child’s body while they are in the hospital or during follow-up. The goal is to better understand dosing and drug exposure in critically ill children.
ParisAges 1 day–18 years - NCT02265770RecruitingPhase 2/Phase 3
Treatment plan for children with brain ependymoma after surgery
This trial tests different follow-up treatments for children with brain ependymoma after their initial surgery. Which treatment you get depends on how much tumor is left (if any) and whether the child can safely receive radiation and chemotherapy.
GrazAges Up to 22 years - NCT03739827Recruiting
Study rare solid tumors and collect your health samples
This study follows people (and sometimes family members) connected to rare solid tumors and collects health information and samples (biospecimens). It helps researchers understand how these cancers develop and builds resources for future research, which may benefit you by contributing to better tailored care for rare cancers.
Bethesda, MarylandAges 4 weeks+ - NCT02544100Recruiting
Study for newborns with brain or nervous system problems
This study enrolls newborns (within the first 28 days of life) who have specific brain or nervous system conditions. It tests how these conditions are tracked and studied, which may help improve care and understanding over time.
Shanghai, Shanghai MunicipalityAges Up to 4 weeks - NCT06020716RecruitingPhase 4
Antibiotics for chronic wet cough in toddlers
This study tests whether the antibiotic Augmentin helps children aged 9 months to 3 years with long-lasting wet cough (more than 4 weeks). It aims to find better ways to treat and understand this common problem in toddlers.
ÅlesundAges 9 months–3 years - NCT06473298Recruiting
Light tracking therapy for kids with one-sided muscle tightness
This study tests a special light-tracking activity to help children with spastic hemiplegia (tightness on one side) improve their movement. It's for kids ages 4–7 who can walk and have mild muscle tightness.
CairoAges 4–7 - NCT00903110Recruiting
Long-term safety registry for Increlex in children
This study is a registry that follows children and teens with severe IGF-1 deficiency who use Increlex (or specific GH gene deletion situations) to better track long-term safety and effectiveness. You would likely join if your child is already starting or planning Increlex and is not in other growth-related drug trials.
Orange, CaliforniaAges 2–18 - NCT04469530RecruitingPhase 2
Sirolimus plus low-dose chemotherapy for high-risk childhood tumors
This Phase 2 study tests whether sirolimus combined with low-dose (“metronomic”) chemotherapy can help children and young adults with certain high-risk solid tumors stay in remission or reduce recurrence risk. It is designed for people whose cancer has responded well to initial treatment, with only minimal or no visible disease on scans.
Atlanta, GeorgiaAges 1–30 - NCT06468046Recruiting
Empowered Mom: A mental health program for migrant mothers
This study tests a new program called 'Mama Empoderada' (Empowered Mom) to help prevent depression and anxiety in migrant mothers who have young children. If you join, you'll learn skills to support your mental health and bond with your child.
Tijuana, Estado de Baja CaliforniaAges 18–99 - NCT06489106Enrolling by invitation
Spinal stimulation to improve hand function in kids with spinal cord injury
This study tests a noninvasive spinal stimulation device to help children with spinal cord injury regain hand strength and control. It may improve grip and daily activities.
Louisville, KentuckyAges 7–12 - NCT03528525Recruiting
Study of breathing-related rare genetic diseases in Chinese children
This registry study collects and stores samples from children with breathing-related rare genetic (inherited) diseases to learn more over time. It may help researchers better understand these conditions and improve future care, especially through long-term follow-up.
Beijing, Beijing MunicipalityAges 1 month–18 years - NCT07666438Recruiting
Lung infections in children with chronic lung disease of prematurity
This study looks at children born very early who have chronic lung disease (BPD) and get a lung infection. Doctors want to learn more about how these infections affect breathing and health over time.
Bologna, BolognaAges 4 weeks–7 years
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Common questions
- Are there clinical trials for children?
- Yes. Clin2 currently lists 3,086 recruiting children studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a children trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a children trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.