Clinical trials
Nephrotic Syndrome in Children clinical trials
Below are recruiting nephrotic syndrome in children clinical trials, each written for real people, not researchers. We’re tracking 27 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07087314RecruitingPhase 2
Study of an injection for nephrotic syndrome in children
This study tests an injection (SG301) that targets a protein called CD38 to help children whose nephrotic syndrome keeps coming back or depends on steroids. The goal is to see if the treatment can reduce relapses and the need for steroids.
Hangzhou, ZhejiangAges 6–18 - NCT05734794RecruitingPhase 3
Rituximab for new childhood nephrotic syndrome
This trial studies whether rituximab alone can help children with new-onset idiopathic nephrotic syndrome. It compares the treatment approach in order to see if it improves kidney recovery and reduces disease activity.
Hangzhou, ZhejiangAges 2–17 - NCT04571658Recruiting
NEPTUNE Match study linking you to possible kidney research trials
This study is an add-on process that uses information from the NEPTUNE kidney study to see whether you might be able to join other kidney research trials. It may help connect eligible people with appropriate new treatment studies when they become available.
Atlanta, GeorgiaAges 1–80 - NCT05505500Recruiting
Parent and patient interviews for childhood kidney swelling
This study uses interviews to understand how swelling from nephrotic syndrome affects daily life for children and their caregivers. It may help researchers design better care by capturing the patient and parent perspective.
Ann Arbor, MichiganAges 2 years+ - NCT05583942Recruiting
Nerve stimulation trial for children with steroid-resistant kidney syndrome
This pilot study tests a device that stimulates nerves in the ear to help children with steroid-resistant nephrotic syndrome. It may improve urine protein and kidney-related outcomes for kids whose standard steroid treatment does not work.
New Hyde Park, New YorkAges 3–17 - NCT05588063Recruiting
Device-based nerve stimulation for relapse-preventing kidney disease in kids
This trial tests whether a small non-surgical device can help keep children with steroid-sensitive nephrotic syndrome in remission. If it works, it could lower the chance of relapse (kidney flare-ups) and help maintain kidney health.
New Hyde Park, New YorkAges 3–17 - NCT05772871RecruitingPhase 4
Prednisone plus herbal granules for children with nephrotic syndrome
This trial tests whether adding Huaiqihuang granules to prednisone can improve outcomes for children with primary, hormone-sensitive nephrotic syndrome. It also closely monitors safety to see if the combination causes fewer or more side effects than usual care.
Hefei, AnhuiAges 1.5 years–18 years - NCT05843968RecruitingPhase 2
Rituximab or mycophenolate for steroid-dependent childhood kidney syndrome
This trial tests whether rituximab works as well as mycophenolate in children whose nephrotic syndrome (kidney condition) comes back when steroid medicines are reduced. It aims to find the safest and most effective option during a relapse.
Chongqing, Chongqing MunicipalityAges 3–16 - NCT06079788RecruitingPhase 3
ACTH for children with frequently relapsing nephrotic syndrome
This trial tests if a hormone called ACTH can help children with nephrotic syndrome who have frequent relapses or need steroids to stay in remission. It aims to find a treatment that may reduce the need for steroids and prevent relapses.
Wuhan, HubeiAges 2–14 - NCT06125405RecruitingPhase 3
Telitacicept for children with frequently relapsing nephrotic syndrome
This trial tests a new drug called telitacicept to help children whose nephrotic syndrome keeps coming back often or who need steroids to stay in remission. The goal is to see if it can keep urine protein levels low and reduce relapses.
Hangzhou, ZhejiangAges 2–18 - NCT06325098Recruiting
Personalized diagnosis for nephrotic syndrome
This study aims to improve how doctors diagnose nephrotic syndrome by using a personalized workflow. If you have nephrotic syndrome and are under 40 years old, this trial might help find the best treatment for your specific type.
FlorenceAges 1 month–40 years - NCT06530004Recruiting
Rituximab for childhood nephrotic syndrome: a follow-up study
This study follows children with nephrotic syndrome (a kidney condition causing swelling) who are being treated for the first time with rituximab. It aims to see how well the medication works long-term.
Xiamen, FujianAges 1–18 - NCT06607991RecruitingPhase 1
Blinatumomab for children with steroid-resistant nephrotic syndrome
This trial tests a drug called blinatumomab for children with a kidney condition that doesn't respond to standard treatments. It aims to see if it can help when other drugs have failed or caused side effects.
Hangzhou, ZhejiangAges 2–17 - NCT06622915Recruiting
Heart health in kids with kidney condition
This study looks at how different types of nephrotic syndrome affect heart function in children. It may help doctors understand the heart risks in kids who need steroids for a long time compared to those whose condition doesn't respond to steroids.
SohagAges 2–14 - NCT07091175RecruitingPhase 2
Dupilumab for nephrotic syndrome in children
This trial tests if dupilumab can help children with nephrotic syndrome who still have relapses despite standard treatments. It aims to find a better way to control the disease and reduce steroid side effects.
Singapore, SingaporeAges 6–18 - NCT01605266Recruiting
Study of insights in children with nephrotic syndrome
This study looks at children’s experiences and understanding of nephrotic syndrome using questionnaires. It aims to learn what helps families and children, which could improve care over time.
Brampton, OntarioAges 6 months–18 years - NCT07516964Recruiting
Studying autoimmune kidney disease in children and adults
This study collects medical information and samples from patients with podocytopathy—a type of autoimmune kidney disease that causes protein leakage into urine. Researchers will analyze your medical records and any blood or kidney tissue samples you've already had to better understand the disease and find better treatments.
Rochester, MinnesotaAges birth–99 years - NCT07206537Recruiting
Vitamin K2 to prevent steroid bone loss in children
This study tests whether vitamin K2 can help prevent bone loss caused by steroid treatment in children with nephrotic syndrome. If your child meets the requirements, taking vitamin K2 may protect their bones while they receive steroids.
CairoAges 1–16 - NCT04174066Recruiting
Study on kidney damage in children and adults with MGLS or FSGS
This trial collects medical data and blood/urine samples from patients with minimal change disease or focal segmental glomerulosclerosis (FSGS) to better understand how the immune system damages kidney cells.
NiceAges 1 year+ - NCT06792799RecruitingEarly Phase 1
CAR-NK cells for B-cell autoimmune diseases
This early phase trial tests a new treatment made from immune cells (CAR-NK cells) that target and destroy overactive B cells. It may help people with lupus, certain kidney diseases, or nephrotic syndrome that hasn't responded to standard therapies.
Hangzhou, ZhejiangAges 3 years+ - NCT06553898RecruitingPhase 1
CAR-T cell therapy for hard-to-treat kidney disease
This trial tests a new CAR-T cell treatment for children and adults with steroid-resistant nephrotic syndrome (SRNS), a kidney condition that doesn't get better with standard medicines. The goal is to see if this therapy can help improve kidney function when other treatments have failed.
Hangzhou, ZhejiangAges 2 years+ - NCT07586267RecruitingEarly Phase 1
CAR-T cell therapy for autoimmune blood diseases
This early-stage trial tests a new type of cell therapy (CAR-T cells) designed to treat severe autoimmune diseases where the immune system attacks the body's own organs. The therapy targets specific immune cells (B cells) that may be causing the disease. It may help patients who haven't improved with standard treatments or can't tolerate them.
Hangzhou, ZhejiangAges 3 years+ - NCT07305116RecruitingPhase 1
CAR T-cell therapy for autoimmune diseases
This trial tests a new immune therapy called CAR T-cells that target two proteins (CD19 and BCMA) to treat autoimmune diseases like lupus, nephrotic syndrome, and others. It is for people whose standard treatments have not worked well enough.
Hangzhou, ZhejiangAges 3 years+ - NCT07507201RecruitingEarly Phase 1
Car-T cells for autoimmune diseases like lupus
This trial tests whether specially-engineered immune cells (CAR-T cells) can help people with certain autoimmune diseases that haven't gotten better with standard treatments. The cells are designed to target and remove faulty B cells that are causing the immune system to attack the body.
Hangzhou, ZhejiangAges 3 years+
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Nephrotic Syndrome in Children trials by city
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Nephrotic Syndrome in Children trials by state
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Common questions
- Are there clinical trials for nephrotic syndrome in children?
- Yes. Clin2 currently lists 27 recruiting nephrotic syndrome in children studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a nephrotic syndrome in children trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a nephrotic syndrome in children trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.