Clinical trials
Congenital Heart Disease in Children clinical trials
Below are recruiting congenital heart disease in children clinical trials, each written for real people, not researchers. We’re tracking 85 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07214376Recruiting
Nerve ablation for pulmonary hypertension from left heart disease
This trial tests a device that uses a catheter to deliver energy to nerves around the pulmonary arteries, aiming to reduce high blood pressure in the lungs caused by left heart failure. It is for people with ongoing heart failure symptoms despite optimal medications.
Tucson, ArizonaAges 18–85 - NCT06542120Recruiting
Child health body sounds study
This study looks at how well a computer system can check children's health by listening to body sounds, like those from the heart, lungs, or belly. It is testing an AI system to see if it works well as an extra check alongside regular medical care.
Wuhan, HubeiAges Up to 18 years - NCT06153459Recruiting
Delayed cord clamping for babies with heart disease
This study looks at how long to wait before clamping the umbilical cord in babies born with a heart condition. It helps doctors understand the best timing for these newborns.
Birmingham, AlabamaAges 9 months–10 months - NCT06080074RecruitingPhase 2
Emergency heart-lung machine study for children with severe heart failure
This study tests a specific heart-lung machine called Cardiohelp to help children with severe heart failure. It looks at how well the machine works and whether a blood thinner (either heparin or bivalirudin) is safer and more effective.
Palo Alto, CaliforniaAges birth–16 years - NCT04216927RecruitingPhase 3
Neonates on heart-lung bypass get NO to prevent kidney injury
This Phase 3 study tests whether not giving nitric oxide during heart-lung bypass in newborns helps reduce the risk of acute kidney injury. It focuses on newborns having heart surgery for congenital heart disease.
Cincinnati, OhioAges 1 day–1 month - NCT04040452RecruitingPhase 4
Continuous versus intermittent ketorolac for kids’ heart surgery pain
This study compares two ways of giving ketorolac (a pain medicine) to young children after heart surgery—continuous drip versus doses at set times. It aims to find which approach controls pain better with fewer side effects.
Phoenix, ArizonaAges 3 months–4.9 years - NCT04604418Recruiting
Tracking outcomes during non-heart procedures in children with heart defects
This study looks at how children with congenital heart disease do during routine non-heart procedures, including medical or minor treatments that are not heart-related. It also measures how much health care they use afterward, which may help improve care planning for families.
Los Angeles, CaliforniaAges Up to 21 years - NCT06015191Recruiting
Remote heart rehab for teens with congenital heart disease
This trial tests a home-based cardiac rehab program for adolescents with certain types of congenital heart disease. It aims to help you exercise safely and improve your fitness using online coaching and monitoring.
Kansas City, MissouriAges 12–19 - NCT07029230Recruiting
Blood test during heart surgery to predict heart failure in kids
This study looks at a substance called sST2 in the blood of children having heart surgery. The goal is to see if sST2 levels can help doctors predict heart failure after surgery.
Zurich, Canton of ZurichAges Up to 18 years - NCT07572435Recruiting
Remote Heart Exercise Program for Kids With Heart Surgery
This study tests whether kids aged 8–18 who had complex heart surgery can safely improve their fitness and well-being using exercise activities at home through a mobile app or video. The goal is to help them become more active after surgery.
SeoulAges 8–18 - NCT07375602Recruiting
AI tool to predict complications after VSD closure in children
This study uses artificial intelligence to predict complications in children who have had a specific type of hole in the heart (called a perimembranous ventricular septal defect) repaired with a catheter-based procedure. The goal is to help doctors better identify which children might have problems after the procedure.
Shanghai, Shanghai MunicipalityAges Up to 18 years - NCT06711666Recruiting
Maternal mental health and baby's brain in heart disease
This study looks at how a mother's mental health during pregnancy may affect the brain development of babies with a serious heart condition called critical cyanotic congenital heart disease (CHD). It aims to understand this link to improve support for families.
MarseilleAges Up to 50 years - NCT07716488Recruiting
Screening for high cholesterol in children with chronic conditions
This study screens children and teens with certain chronic conditions (like heart defects or inflammatory bowel disease) for early signs of high cholesterol or other lipid problems. The goal is to find and manage these risks sooner.
JenaAges 6–18 - NCT03626480Recruiting
Nutrition support before and after heart surgery for babies
This trial studies a nutrition plan given around the time of heart surgery for babies with congenital heart disease. It may help improve how babies grow and recover by supporting feeding before and after the operation.
Hangzhou, ZhejiangAges 1 day–1 year - NCT04217421RecruitingPhase 3
Allopurinol for newborns needing heart surgery with bypass
This trial tests whether the medicine allopurinol can protect the brain and heart in newborns with serious congenital heart disease who need heart surgery soon after birth. It may help reduce injury during and around surgery that uses a heart-lung machine (cardiopulmonary bypass).
GroningenAges Up to 1 month - NCT04299828Recruiting
Study of inflammation activity during complex heart surgery
This study measures how active white blood cells and inflammation are during complex heart surgery using a heart-lung machine. It may help doctors better understand what triggers inflammation during surgery and how to improve care.
Boston, MassachusettsAges Any age - NCT04467671RecruitingPhase 2
Tested new blood vessel graft for a heart surgery
This trial studies whether a newer “tissue-engineered” blood vessel graft is safe and works well in children who need a specific heart surgery connection outside the heart. It may help by offering a new type of graft, but your team will screen for size and medical factors first.
Columbus, OhioAges Any age - NCT04575883Recruiting
Bike interval training for teens with repaired heart defects
This study tests a structured “interval” bike exercise program to see if it’s safe and helpful for teens with certain repaired congenital heart conditions. It may help improve fitness while closely monitoring heart symptoms during training.
Edmonton, AlbertaAges 10–18 - NCT05241418Recruiting
MRI study of heart scar using gadolinium in repaired heart defects
This trial looks at heart MRI images to see whether a contrast dye (gadolinium) can highlight scar-like areas after congenital heart problems have been repaired. It may help doctors better understand healing and plan care, especially for future heart procedures.
Boston, MassachusettsAges 13 years+ - NCT05258981Recruiting
MRI and testing study linking genes and thinking in adults
This study looks at how patterns on brain MRI scans and genes relate to thinking and test performance in adults. It may help researchers better understand long-term brain and cognitive outcomes and how they differ between people with specific early-life heart conditions and healthy controls.
Boston, MassachusettsAges 24–35 - NCT05687292Recruiting
Decision tool to shorten breathing machine time in children
This study tests whether a computer “decision support” tool can help doctors safely reduce how long a child stays on a breathing machine after heart surgery. It may help children get off mechanical ventilation sooner and recover faster.
Boston, MassachusettsAges 1 day–12 years - NCT05702203Recruiting
Music therapy for newborns with congenital heart disease
This trial tests whether creative music therapy can help newborn babies who have congenital heart disease (CHD) while they are in intensive care. It focuses on babies who are otherwise very young and in the NICU or PICU, regardless of CHD severity.
ZurichAges 1 minute–4 weeks - NCT05996211Recruiting
Swiss Study on Brain Development in Children with Heart Defects
This study follows children with severe heart problems born recently to see how their brain development progresses. It helps doctors understand what support these children might need as they grow.
BernAges 1 week–1 month - NCT05997680Recruiting
Yoga for attention in kids with heart disease
This study tests if a parent-child yoga program can help improve attention in children aged 4 to 6 with congenital heart disease who have attention difficulties. You and your child would attend yoga sessions together for 8 weeks.
Montreal, QuebecAges 4–6
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Common questions
- Are there clinical trials for congenital heart disease in children?
- Yes. Clin2 currently lists 85 recruiting congenital heart disease in children studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a congenital heart disease in children trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a congenital heart disease in children trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.