Clinical trials
Cleft Lip clinical trials
Below are recruiting cleft lip clinical trials, each written for real people, not researchers. We’re tracking 29 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05081258Recruiting
Tests presurgery shaping for newborn cleft lip and palate growth
This study looks at whether a presurgery orthodontic shaping method affects how newborns with a cleft lip and palate grow over time. It may help clinicians decide on the best early treatment approach.
Erlangen, BavariaAges 1 day–2 years - NCT07048418Recruiting
Nose job results in adults born with a cleft lip and palate
This trial asks adults who had a nose job as teens or children, after being born with a cleft lip and palate, to rate how they look and feel about their nose. Their answers will help doctors understand how these surgeries affect patients long-term.
MontpellierAges 18–30 - NCT01601171Recruiting
Genetic study of reproductive problems and cleft lip or palate
This study looks at genetic (inherited) causes of certain hormone and reproductive conditions, including Kallmann syndrome and cleft lip/palate. You might be asked for medical and family history and possibly a DNA sample, helping researchers find what drives these conditions.
Lausanne, Canton of VaudAges Any age - NCT02702869Enrolling by invitation
Study of improving care for common facial clefts
This trial is part of a quality-improvement and research program for people with typical facial clefts. It aims to help improve how care is organized and measured across treatment centers, which may benefit future patients and help your team deliver coordinated care.
Gainesville, FloridaAges 1 day–22 years - NCT06510881Recruiting
One surgery vs. multiple surgeries for cleft nose and gum repair
This trial compares doing a single surgery to fix both the nose and gum problems caused by a cleft lip and palate, versus doing multiple surgeries over time. It aims to find out which approach works better for children and teens.
AsyutAges 5–18 - NCT04234971RecruitingPhase 4
Compare costs of bone grafting for cleft jaw repair
This study looks at whether alveolar bone graft surgery is cost-effective for people with cleft lip and palate. It may help clinics choose the most practical approach for the best outcomes while managing overall costs.
Houston, TexasAges 6–15 - NCT07692061Enrolling by invitation
Speech therapy study for Cantonese-speaking kids with cleft palate
This study tests a new speech therapy program for children and teens (ages 4–17) who had cleft palate repair before age 2 and have certain speech sound errors. It aims to improve their speech clarity and communication.
Shatin, New TerritoriesAges 4–17 - NCT05837780Enrolling by invitation
Different braces techniques for babies with a cleft lip and palate
This trial compares two different techniques for making a molding device (a baby “nasal/cheek shape” support) for newborns with a cleft lip and palate on one side. It may help your baby get a better starting nose and lip shape during early treatment.
MinyaAges 1 week–1 month - NCT06970158Recruiting
Smart scan for babies with one-sided cleft lip and palate
This study tests using a smart camera (artificial intelligence) to help plan surgery for newborns with a single-sided cleft lip and palate. Your baby will have a quick and painless 3D scan of their mouth to guide their doctors, and you'll be closely supported throughout.
ChennaiAges 1 day–6 months - NCT05825170Recruiting
Hyaluronic acid lip filler for lip deformity after cleft surgery
This trial tests a hyaluronic acid filler (placed in the lips) to improve lip shape in people who had cleft lip and palate surgery. It looks at how well the filler works and how safe it is for your lips and surrounding skin.
Lille, NordAges 18 years+ - NCT06905678Recruiting
Cleft palate cost and emotion study
This study looks at how having a cleft palate affects your family's finances and emotions. You may be able to join if you are 5, 12, or 18 years old and have a cleft lip or palate.
GhentAges 4–22 - NCT06338319Enrolling by invitation
Book sharing study for toddlers with cleft palate
This study tests whether a book-sharing program can help toddlers (20-32 months) who had cleft palate repair improve their language and communication skills. Families will use a smartphone or tablet to record and send videos.
Seattle, WashingtonAges 1.7 years–2.7 years - NCT07781566Recruiting
Speech therapy intensity for cleft palate speech errors in children
This study looks at how well two different intensities of speech therapy work for children with a cleft palate who have speech sound errors. It aims to find the best way to help your child speak more clearly.
Ghent, East-FlandersAges 4 years+ - NCT07557576Recruiting
Pain management approaches for children having cleft surgery
This study compares two types of anesthesia (with and without opioid painkillers) for children undergoing cleft lip or palate surgery. The goal is to see which approach better controls pain after surgery and reduces agitation as the child wakes up.
ZagrebAges 3 months–7 years - NCT07340008Recruiting
Comparing medicines for calm stitch removal in children after cleft surgery
This study compares three different medicines (ketamine, nalbuphine, and dexmedetomidine) to help keep children calm and comfortable while their stitches are removed after cleft surgery. It may help find the best way to reduce pain and anxiety in young children during this procedure.
LjubljanaAges 6 months–3 years - NCT04342234Recruiting
Neural network tool to measure cleft palate from scans
This trial studies a computer “neural network” that uses existing dental impressions, scans, and photos to measure cleft palate features. The goal is to reduce the amount of repeated cleft lip and palate clinic work for patients and families.
BaselAges Any age - NCT06994754Recruiting
Expanding the upper jaw with clear aligners in cleft lip and palate patients
This trial tests whether clear aligners can safely widen the upper jaw in children with cleft lip and palate who still have some baby teeth. It may be an option for those needing jaw expansion without braces.
Cairo, SelectAges 6–12 - NCT05775679Recruiting
CLEFT-Q survey study for people with cleft lip or palate
This study tests how consistently and clearly a questionnaire (CLEFT-Q) measures your symptoms and how well treatment helps. It may help researchers improve care for people who need a planned second surgery for the nose, lips, jaw, or speech.
Malmö, Skåne CountyAges 8–29 - NCT06408337RecruitingPhase 1/Phase 2
Biocleft for cleft palate repair in children
This trial tests a new treatment called BIOCLEFT, made from your child's own cheek cells, to help repair a complete cleft palate on one side. It aims to see if the treatment is safe and works better than standard surgery.
Granada, Spain/GranadaAges 10 months–1.2 years - NCT04422847Recruiting
3D printed tools to help anesthesia for children with cleft face
This study uses computer planning and 3D printed models to help the anesthesia team manage breathing and airway safety during a child’s cleft-related surgery. It may improve planning and safety by matching the anesthesia plan to your child’s anatomy.
Brno, Jihomoravská KrajAges Up to 2 years - NCT03065686Recruiting
Study genes in cleft lip or palate without a known cause
This study looks for genetic reasons behind cleft lip and/or cleft palate when the cause is not known. The results may help researchers understand risk factors and improve future care.
AmiensAges Any age - NCT06105099Recruiting
Speech therapy for children with cleft palate
This study tests a special speech therapy program for children with a cleft palate who have speech errors. The therapy focuses on improving speech sounds and seeing if the improvements last over time.
GhentAges 4–12 - NCT06381713Recruiting
Speech therapy for children with cleft palate
This study compares two types of speech therapy for children with cleft palate. It looks at how well each type works and how much it costs, to help find the best way to improve your child's speech.
GhentAges 4–12 - NCT06895395Recruiting
Speech therapy for kids with cleft palate
This study compares different types of speech therapy for children born with a cleft palate who have developed certain speech errors. The goal is to learn which therapy works best from the perspective of the child, their family, and the speech therapist.
GhentAges 4–12
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Common questions
- Are there clinical trials for cleft lip?
- Yes. Clin2 currently lists 29 recruiting cleft lip studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cleft lip trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cleft lip trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.