Clinical trials
Colitis clinical trials
Below are recruiting colitis clinical trials, each written for real people, not researchers. We’re tracking 320 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06228352Recruiting
Bile acids and gut bacteria in C. difficile with ulcerative colitis
This study looks at how bile acids and gut bacteria relate to C. difficile infection in children with ulcerative colitis. It aims to find better ways to predict and treat these infections.
ParisAges Up to 17 years - NCT06231264Recruiting
Electrical acupressure for mild to moderate colitis
This trial tests whether a gentle electrical stimulation device (like acupuncture without needles) on the skin can help people with mild to moderate ulcerative colitis who haven't gotten better with standard treatments.
Xi'an, ShaanxiAges 18 years+ - NCT06298461RecruitingPhase 4
Comparing bowel preps for Crohn's and colitis patients
This trial compares two different bowel preparation solutions (2L-PEG and oral sulfate solution) for people with Crohn's disease or ulcerative colitis who are having a colonoscopy. The goal is to find which preparation works better and is more comfortable for patients with these conditions.
Winnipeg, ManitobaAges 18 years+ - NCT06315179Recruiting
Spatial gene study for inflammatory bowel disease
This study looks at tissue samples from people with suspected Crohn's disease, ulcerative colitis, or indeterminate colitis. The goal is to understand these conditions better and may lead to improved treatments.
Seattle, WashingtonAges 6–21 - NCT05679622Recruiting
Stool transplant study for children with mild to moderate ulcerative colitis
This trial studies whether transferring healthy stool bacteria into the gut (fecal microbiota transplantation, or FMT) can improve symptoms in children with ulcerative colitis. It may help by changing gut bacteria, especially for children who are newly diagnosed or who didn’t respond to standard treatments.
WuhanAges 2–16 - NCT06335160Recruiting
Mebendazole for mild to moderate ulcerative colitis
This study tests adding a medicine called mebendazole (normally used for parasites) to standard mesalamine treatment for people with mild or moderate ulcerative colitis. The goal is to see if it helps control inflammation better than mesalamine alone.
TantaAges 18–75 - NCT06359808Recruiting
Sleep Problems in Ulcerative Colitis Patients
This study looks at sleep problems in people with ulcerative colitis (a type of inflammatory bowel disease). It aims to understand how sleep affects your condition and may help find better ways to manage both.
Xi'an, ShaanxiAges 18–65 - NCT06405087RecruitingPhase 3
Long-term study of vedolizumab for children with IBD
This study is for children and teenagers with ulcerative colitis or Crohn's disease who have already completed a previous vedolizumab study and are doing well. It will look at the long-term safety and effectiveness of continuing vedolizumab treatment.
Phoenix, ArizonaAges 2–17 - NCT06420375RecruitingPhase 2
New treatment for active ulcerative colitis
This trial tests a new treatment for people with ulcerative colitis (UC) whose disease is active despite taking only mesalamine or sulfasalazine. It aims to find a therapy that can reduce inflammation and improve symptoms.
Chestnut Hill, MassachusettsAges 18–75 - NCT06421818RecruitingPhase 2
Baitouweng Decoction for ulcerative colitis with damp-heat
This trial tests a traditional Chinese herbal formula called Baitouweng Decoction for people with mild to moderate ulcerative colitis who also have a specific pattern of symptoms called 'damp-heat' in the large intestine. It aims to see if the medicine can help reduce inflammation and improve symptoms.
Nanjing, JiangsuAges Any age - NCT06453317RecruitingPhase 2
Comparing UC treatments: infliximab vs ustekinumab vs both
This study compares an existing UC medication (infliximab) with a newer one (ustekinumab) and a combination of both. The goal is to see which works best for moderate to severe UC when other treatments have failed.
LodzAges 18–64 - NCT07692165RecruitingPhase 1/Phase 2
Testing INT-210 capsules for active ulcerative colitis
This trial tests an experimental capsule called INT-210 for people with active ulcerative colitis (UC) who haven't improved enough with standard treatments. It aims to see if the drug can help control symptoms and improve the condition.
Guangzhou, GuangdongAges 18–75 - NCT06398626Recruiting
Observational study of etrasimod for ulcerative colitis
This study watches how well etrasimod works for adults with moderate to severe ulcerative colitis (UC). You must already be prescribed etrasimod by your doctor, and the study collects information through a web-based tool.
Mesa, ArizonaAges 18–64 - NCT07296315RecruitingPhase 2
Testing a new treatment for mild-to-moderate ulcerative colitis
This study tests an investigational drug for people with active mild-to-moderate ulcerative colitis. It aims to see if the drug can improve symptoms without needing advanced treatments like biologics.
Miami, FloridaAges 16 years+ - NCT06488625RecruitingPhase 2/Phase 3
Nicotinamide for mild to moderate ulcerative colitis
This trial tests whether a special oral form of nicotinamide (a type of vitamin B3) can help control mild to moderate ulcerative colitis. The pill is designed to release the medication in the lower part of your gut, where UC often affects. Participation involves taking the study drug and having regular checkups to see how your symptoms and inflammation respond.
Kiel, Schleswig-HolsteinAges 18–80 - NCT06495658Recruiting
Prebiotics for ulcerative colitis symptoms
This trial tests whether a prebiotic supplement can improve symptoms of ulcerative colitis. It may be a good option for people with active symptoms who are already on stable medications.
Los Angeles, CaliforniaAges 18–85 - NCT06515210Recruiting
Fibre supplement for ulcerative colitis inflammation
This study tests whether a special fibre supplement can reduce inflammation in people with active ulcerative colitis. You take the supplement daily for a few weeks, and researchers check how it affects your symptoms and gut health.
Edmonton, AlbertaAges 14 years+ - NCT06516237Recruiting
New imaging for fibrosis in ulcerative colitis
This study looks at new ways to detect scarring (fibrosis) in the bowel using advanced imaging and tests. It may help doctors better understand and monitor ulcerative colitis. If you are already having a colonoscopy, you may be able to join.
Milan, LombardyAges 18 years+ - NCT06581328RecruitingPhase 4
Study of vedolizumab for ulcerative colitis or Crohn's disease
This study tests the drug vedolizumab in adults with moderate to severe ulcerative colitis or Crohn's disease. It aims to see how well the medicine works in a community (non-hospital) setting.
Birmingham, AlabamaAges 18–80 - NCT06595719Recruiting
Probiotics plus standard care for mild to moderate UC
This trial tests whether adding a multi-strain probiotic supplement to your usual care can help manage mild to moderate ulcerative colitis (UC). It lasts 12 weeks and requires you to stay on your current medications without changes.
Cheras, Kuala LumpurAges 18–90 - NCT05287126RecruitingPhase 2
Etrasimod for teens with active ulcerative colitis
This trial tests whether etrasimod can improve ulcerative colitis (UC) symptoms in adolescents with moderate to severe, active disease. It may help reduce inflammation and disease activity, especially if current treatments aren’t working well enough.
Little Rock, ArkansasAges 12–17 - NCT06604273RecruitingPhase 2/Phase 3
Studying bowel scarring in ulcerative colitis with filgotinib
This trial tests if filgotinib can help reduce intestinal scarring in people with active ulcerative colitis. It aims to understand fibrosis and find better ways to monitor treatment.
Amsterdam, North HollandAges 18 years+ - NCT06609447RecruitingPhase 4
Probiotic with vedolizumab for moderate ulcerative colitis
This study tests whether adding a special probiotic (VSL#3) to vedolizumab helps people with moderate ulcerative colitis more than vedolizumab alone. You may qualify if you are already planning to start vedolizumab and haven't responded well enough to other treatments.
Beijing, Beijing MunicipalityAges 18–85 - NCT06636656RecruitingPhase 2
Testing a new drug for ulcerative colitis after other treatments failed
This study tests a new medication called BI 3032950 for people with ulcerative colitis who have already tried other advanced treatments (biologics or targeted therapies) that didn't work well enough or caused problems. The goal is to see if the new drug is safe and helps control inflammation in the colon.
Scottsdale, ArizonaAges 18–80
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Common questions
- Are there clinical trials for colitis?
- Yes. Clin2 currently lists 320 recruiting colitis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colitis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colitis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.