Study of AC-101 tablets for moderate to severe ulcerative colitis
Part of Digestive system clinical trials.
This trial tests a new tablet called AC-101 for people with active moderate to severe ulcerative colitis. It aims to see if the drug can reduce symptoms like diarrhea and bleeding and help the gut heal.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have ulcerative colitis diagnosed at least 3 months ago and confirmed by a scope and biopsy.
- Your disease must be active, with a Mayo score of 5 to 9, meaning moderate symptoms like frequent stools and bleeding.
- The inflammation in your colon must extend at least 6 inches from the anal opening.
- You must be on stable doses of 5-ASA or oral steroids (like prednisone ≤20 mg/day) for 2 weeks before starting.
- You can be new to biologics or have been off them for at least 5 half-lives.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests an oral tablet called AC-101 for people with moderate to severe ulcerative colitis. It aims to see if the drug can reduce inflammation in the colon and improve symptoms.
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