Clinical trials
Corneal Diseases clinical trials
Below are recruiting corneal diseases clinical trials, each written for real people, not researchers. We’re tracking 24 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04251143Recruiting
Study for corneal disease and corneal thinning
This study looks at people with corneal disease, especially corneal thinning that can change how the eye focuses light. It may help researchers understand treatments and care plans for these conditions.
Dresden, SaxonyAges 18–65 - NCT06211218Recruiting
AI screening for multiple corneal diseases
This study uses artificial intelligence to look at slit-lamp images of your eye to screen for different corneal diseases. It may help find problems early when they are easier to treat.
Tianjin, Tianjin MunicipalityAges Any age - NCT06983652Recruiting
Validating a new scan for corneal scars and swelling
This study tests a new scanning technology (terahertz) to see if it can detect and measure corneal scars and swelling (edema). If you have one of these conditions, you may help validate a faster, non-invasive way to monitor your eye health.
SingaporeAges 21 years+ - NCT07024719Recruiting
4D microscope OCT during eye surgery study
This trial tests a new microscope that takes 3D images of the eye during surgery. It may help doctors see eye details better while operating.
Durham, North CarolinaAges 18 years+ - NCT05573802RecruitingPhase 1/Phase 2
Belantamab and other medicines for new multiple myeloma
This early-phase study tests how safe and effective belantamab mafodotin is when combined with lenalidomide and dexamethasone, plus a medicine called nirogacestat, in people with newly diagnosed multiple myeloma who cannot have stem cell transplant. It may help shrink the cancer and improve outcomes, while doctors track side effects.
AthensAges 18 years+ - NCT06451172RecruitingEarly Phase 1
New antibiotic eye drops for drug-resistant eye infections
This trial tests a new type of antibiotic eye drop for people with serious eye infections that don't respond to standard antibiotics. It aims to see if these drops can safely treat the infection and help improve vision.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07149740Recruiting
A study to collect images of eyes for new camera technology
This trial uses a special camera (OCT) to capture detailed images of the eye. It aims to improve eye disease detection. You may join if you have retinal disease, glaucoma, corneal disease, or healthy eyes.
Anaheim, CaliforniaAges 22 years+ - NCT04848740Enrolling by invitation
Tested implant for worsening thin corneas
This trial looks at whether placing a donor-like cornea “lenticule” implant can help people whose cornea is getting worse, becoming thin, and causing blurry or reduced vision. The goal is to see if the implant can improve corneal clarity and vision in progressive disease.
PristinaAges 20–60 - NCT07566806Recruiting
Cord Plasma Eye Drops for Nerve Pain in the Eye
This trial tests whether special eye drops made from cord plasma (a blood product) can reduce chronic eye pain caused by damaged nerves in the cornea (the clear front part of your eye). You may qualify if you have had eye pain for at least 3 months without obvious surface damage.
Singapore, SingaporeAges 21 years+ - NCT06491615Recruiting
eyeGENE study: genetics of rare eye diseases
This study collects DNA samples and medical information from people with rare inherited eye diseases and their close relatives. The goal is to learn more about the genetic causes of these conditions and improve diagnosis and care.
Bethesda, MarylandAges 1 day–120 years - NCT06919081RecruitingPhase 2
Stem cell eye drops for chronic cornea problems
This study tests whether a special substance from stem cells (called secretome) can help heal chronic surface problems on the eye that haven't gotten better with standard treatments. It's for people with a stubborn scratch or defect on the cornea that has lasted more than 14 days.
Chicago, IllinoisAges 18 years+ - NCT07124910RecruitingPhase 3
Comparing two UV light times for corneal crosslinking
This trial tests two different UV light exposure times (18 minutes vs. 24 minutes) during a corneal crosslinking procedure for people with keratoconus or similar corneal thinning conditions. The goal is to see if the shorter time works as well as the longer one.
Atlanta, GeorgiaAges 8 years+ - NCT06841471Recruiting
Role of Corneal Nerves in Dry Eye Disease
This study looks at how the nerves in the front of the eye (corneal nerves) relate to dry eye disease. It compares people with dry eye to those without to understand differences.
OltenAges 18 years+ - NCT07135167RecruitingPhase 3
Epi-ON corneal crosslinking study for people with Down syndrome
This study tests a special light treatment for cornea problems in people with Down syndrome. It aims to strengthen the front of the eye and may help prevent vision loss.
Atlanta, GeorgiaAges 8 years+ - NCT06967792Recruiting
Safety of Terahertz Eye Scan for Blind Eyes
This trial tests a new scanning system that uses safe terahertz waves to look at the cornea. It's for people who are blind in one eye but have a healthy cornea, to see if the scan is safe.
Singapore, SingaporeAges 21 years+ - NCT07780890Recruiting
Measuring eye hydration with light
This study uses a non-invasive imaging technique called Brillouin hydration mapping to measure hydration levels in different parts of the eye. It aims to help doctors better understand how hydration affects eye health and disease.
Boston, MassachusettsAges 20–79 - NCT04591587Enrolling by invitation
Corneal lenticule implant for keratoconus
This trial tests a new surgical procedure using a small piece of corneal tissue (a lenticule) from a donor to strengthen the cornea in people with progressive keratoconus. The goal is to help stop the disease from getting worse.
PristinaAges 20–40 - NCT04700657Recruiting
Study dryness patterns in eye graft-vs-host disease
This study looks at how common and how severe corneal nerve-related dryness is in people with chronic graft-vs-host disease (GVHD) after a stem cell transplant. It may help doctors understand which eye problems are most typical and how best to recognize them early.
Indianapolis, IndianaAges 18 years+ - NCT07435142Recruiting
Urine-derived cells for corneal eye disease
This trial tests if using special cells from your own urine can help repair the inner layer of your cornea (the clear front part of your eye). It may be an option if you have damage to these cells and have already had at least one cornea transplant.
Jinan, ShandongAges 18–85 - NCT06655441RecruitingPhase 4
Trehalose eye drops for dry eye disease
This study tests if a special sugar-based eye drop called trehalose can improve the protective layer of the eye in people with moderate to severe dry eye. It might help strengthen the cornea and reduce discomfort.
Fullerton, CaliforniaAges 18 years+ - NCT06601101RecruitingPhase 3
Insulin drops for faster healing after corneal crosslinking
This trial tests whether insulin eye drops can help the cornea heal faster after corneal crosslinking, a procedure to treat keratoconus. It is for people with keratoconus who do not have diabetes, severe dry eye, or certain other eye conditions.
Campinas, São PauloAges 14 years+ - NCT07634913Recruiting
Mobile App for Eye Disease Detection
This study tests a smartphone-based system designed to help detect diseases affecting the front of the eye. Researchers will develop and refine this mobile tool to see if it can accurately identify common eye conditions using photos taken on a phone or with standard eye-examination equipment.
Guangzhou, GuangdongAges 18 years+ - NCT06860659Enrolling by invitationPhase 4
Hyaluronate eye drops for moderate to severe dry eye
This trial tests whether 0.28% sodium hyaluronate eye drops can help people with moderate to severe dry eye feel better. It's for patients who have significant dry eye symptoms and signs on an eye exam.
Bangkok, BangkokAges 18 years+ - NCT01793168Recruiting
Rare disease registry and history study
This study keeps a registry (a structured list) of people with rare diseases and may also track how the condition changes over time. It can help researchers better understand rare illnesses and find gaps in care, which may improve future treatments.
Sioux Falls, South DakotaAges Any age
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Common questions
- Are there clinical trials for corneal diseases?
- Yes. Clin2 currently lists 24 recruiting corneal diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a corneal diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a corneal diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.