Clinical trials · North Carolina
Critical Illness clinical trials in North Carolina
We’re tracking 12 recruiting critical illness studies with a site in North Carolina — including Phase 1/Phase 2 studies, each written for real people, not researchers.
Recruiting studies in North Carolina
- NCT06751043Recruiting
Testing if fasting before a procedure is needed in ICU patients
This trial tests whether not eating before a procedure (called preoperative fasting) is better than fasting in ICU patients who are already receiving tube feedings. It aims to find out if skipping the fast can help you without causing extra risks.
Winston-Salem, North CarolinaAges 18 years+ - NCT05055830Recruiting
Study blood drug levels in critically ill children
This trial measures how the study medicines move through the body and how they affect the child in the Pediatric Cardiac Intensive Care Unit. It may help doctors choose safer and better dosing for critically ill children.
Durham, North CarolinaAges birth–20 years - NCT04989790Recruiting
Early mobility program for critically ill children in the PICU
This trial tests whether a structured “early mobility” activity plan (“PICU Up!”) helps children who are on a breathing machine recover or feel better while in the pediatric ICU. It aims to see if starting safe movement earlier makes a difference for critically ill kids.
Chapel Hill, North CarolinaAges Up to 18 years - NCT07313956Enrolling by invitation
Breathing machine method study in the ICU
This study looks at how different settings on the breathing machine (ventilator) are used for critically ill adults in the ICU. It may help doctors improve care for people who need a breathing tube.
Winston-Salem, North CarolinaAges 18 years+ - NCT07101640RecruitingPhase 1/Phase 2
Montelukast study for breathing problems in premature infants
This trial tests if the medicine montelukast can help very premature babies on breathing machines. It aims to see if it improves lung development and makes it easier for them to breathe on their own.
Chapel Hill, North CarolinaAges 1 week–4 weeks - NCT06934876Recruiting
Comparing two CO2 detectors during breathing tube placement in critically ill adults
This study compares two ways of checking that a breathing tube is placed correctly in seriously ill adults: one uses a device that shows a waveform on a screen, and the other uses a color-changing test. It may help doctors choose the best method for patients in the emergency room or ICU.
Winston-Salem, North CarolinaAges 18 years+ - NCT05218083Recruiting
Mobile rehab program with interval exercise after COVID-19
This trial tests a coach-supported, phone-based rehabilitation program that includes high-intensity interval-style exercise for people recovering from COVID-19 after a hospital stay. It may help improve breathing, strength, and walking by providing structured exercise at home.
Durham, North CarolinaAges 18 years+ - NCT05440851Recruiting
Testing different treatments for severe breathing failure in ICU
This platform trial studies which treatment works best for adults with sudden, severe breathing failure needing oxygen or a breathing machine in the ICU. It may help patients by matching them to the most appropriate treatment strategy and tracking outcomes to improve care.
Winston-Salem, North CarolinaAges 18 years+ - NCT05673408Recruiting
Check how well a blood pressure cuff reads in critically ill patients
This study tests whether a noninvasive blood pressure (NIBP) cuff gives accurate readings in people being cared for in intensive care or the operating room. It will compare the cuff’s numbers to blood pressure measured through an arterial line in different patient groups.
Winston-Salem, North CarolinaAges Any age - NCT06521086Recruiting
Better nutrition recovery for trauma patients
This study tests if a special nutrition plan helps older adults recover better after a traumatic injury. It aims to improve healing by providing extra nutrition through food and drinks.
Durham, North CarolinaAges 45 years+ - NCT06588556Recruiting
Improving Care for Older Adults in the ICU
This study tests a program to improve communication and support for older adults in the ICU and their families. It may help families feel more supported during a serious illness.
Durham, North CarolinaAges 18 years+ - NCT02182180Recruiting
SC2i tissue and data collection for people needing urgent care
This study collects small samples of tissue and body fluids and related health data from people who need surgery or treatment in an emergency or critical care setting. The goal is to build a resource researchers can use to better understand illness and improve care.
Durham, North CarolinaAges 18 years+
Critical Illness trials by city in North Carolina
Where these studies are running in North Carolina
Institutions with a site for the recruiting critical illness studies listed above.
- Wake Forest University Health Sciences · 5 studies
- Duke University Medical Center · 4 studies
- Duke University Health System · 2 studies
- East Carolina University
- UNC Children's Hospital
- University of North Carolina at Chapel Hill
What taking part in a critical illness study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Critical Illness trials in other states
Common questions
- Are there critical illness clinical trials in North Carolina?
- Yes. We're currently tracking 12 recruiting critical illness studies with a site in North Carolina, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a critical illness study in North Carolina?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in North Carolina to take part?
- Not necessarily. These studies have a site in North Carolina, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a critical illness trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New critical illness studies open in North Carolina regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.