Clinical trials
Crohn’s disease clinical trials
A type of inflammatory bowel disease causing inflammation of the digestive tract. We’re tracking 333 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04508088Recruiting
Study of bones and bone marrow in new Crohn’s
This study looks at how Crohn’s disease affects bones and bone marrow soon after diagnosis. It may help researchers understand disease effects and improve future care, either by comparing you to healthy controls or by tracking changes over time.
Boston, MassachusettsAges 13–20 - NCT05332639Recruiting
Risk tracking test for Crohn’s disease in teens
This study checks whether a personalized tool can estimate someone’s risk for Crohn’s disease before symptoms start. It may help families learn early risk and decide on next steps sooner.
Boston, MassachusettsAges 14 years+ - NCT04777656RecruitingPhase 3
Crohn’s exclusion diet plus usual care for kids
This study tests whether a specific “exclusion diet” (removing certain foods) added to standard treatment can better control unstable Crohn’s disease in children. It may help reduce inflammation and flare-ups when symptoms are not controlled by usual medicines.
BronAges 6–17 - NCT04637438Recruiting
Fecal transplant for Crohn’s around the small and large bowel
This trial studies fecal microbiota transplantation (a transplant of beneficial gut bacteria from a donor) to help people with Crohn’s disease that is causing narrowing (strictures) and/or abnormal tunnels (fistulas) and who need bowel surgery. You may qualify if you’re an adult, planning ileal/ileocecal surgery, and can complete the colonoscopy while not on certain gut-altering medicines.
TampereAges 18–120 - NCT04192825Recruiting
Crohn’s anal drainage care study
This trial studies different care and management approaches for people with Crohn’s disease who have an anal infection or drainage area and are planning a drainage procedure. It may help improve how care is planned around the drainage procedure and follow-up.
RennesAges 18 years+ - NCT05578235Recruiting
Surgery for Crohn’s: hand-sewn vs stapled bowel connection
This trial compares two ways of reconnecting the bowel after removing diseased intestine in people with Crohn’s disease. The goal is to see which method works better for healing and short- and longer-term outcomes.
Almere Stad, FlevolandAges 16 years+ - NCT07833332Recruiting
Comparing two procedures for blocked small bowel in Crohn's disease
This study compares two procedures—endoscopic stricturotomy and balloon dilation—to treat a narrowed section (stricture) in the small bowel caused by Crohn's disease. If you have a partial blockage, this trial aims to see which procedure is better at safely opening the bowel.
Guangzhou, GuangdongAges 18–70 - NCT07824791Recruiting
Predicting return of Crohn's disease after bowel surgery
This study looks at what happens to people with Crohn's disease after they have surgery to remove a diseased part of their intestine. The goal is to find patterns or signs that might help predict whether the disease will come back, which could help doctors plan better follow-up care.
Guangzhou, GuangdongAges 18–70 - NCT06629194Recruiting
Comparing tests to tell intestinal TB from Crohn's disease
This study looks at different scoring systems to help doctors tell the difference between intestinal tuberculosis (a bacterial infection) and Crohn's disease (a chronic inflammatory condition). If you have ulcers in your ileum or colon and are undergoing a colonoscopy, you may be able to help doctors improve how they diagnose these conditions.
Bangkok Noi, BangkokAges 18 years+ - NCT07625293RecruitingPhase 2
DB-3Q for treatment-resistant Crohn's disease
This trial tests a new medicine called DB-3Q for people with Crohn's disease that hasn't responded to standard biologic treatments or causes side effects. The study aims to see if DB-3Q can reduce inflammation and symptoms in people whose disease is hard to control.
St Louis, MissouriAges 18–75 - NCT07629245RecruitingPhase 1/Phase 2
Cell therapy for Crohn's disease fistulas after prior treatment
This trial tests whether injecting your own fat-derived cells combined with a skin graft can heal anal fistulas (abnormal passages near the anus) that didn't respond to or came back after a previous cell therapy study. You must have already participated in the ADICROHN-2 study.
MarseilleAges 18 years+ - NCT07577843RecruitingPhase 3
Testing JNJ-78934804 for moderate to severe Crohn's disease
This study tests a new drug called JNJ-78934804 for people with moderate to severe Crohn's disease who have not responded well to or can't tolerate current treatments. The goal is to see if this drug can reduce inflammation and symptoms in the digestive tract.
Anaheim, CaliforniaAges 18 years+ - NCT07499232RecruitingPhase 3
Guselkumab vs Risankizumab for Crohn's disease
This trial compares two drugs, guselkumab and risankizumab, to see which works better for people with moderate-to-severe Crohn's disease. Both are given as injections and aim to reduce inflammation in the gut.
Dothan, AlabamaAges 18 years+ - NCT07483099RecruitingPhase 2
Study of two drugs for Crohn's disease
This trial tests if taking a new drug (LY4395089) with mirikizumab works better than mirikizumab alone for adults with Crohn's disease. It also looks at the safety of these treatments.
Scottsdale, ArizonaAges 18–80 - NCT07471438Recruiting
MRI comparison for Crohn's disease activity in the ileum
This trial compares two types of MRI scans to see how well they detect inflammation in the small intestine of people with Crohn's disease. It aims to find the best way to assess disease activity without invasive procedures.
AmiensAges Any age - NCT06833450Recruiting
Intestinal ultrasound for monitoring Crohn's disease
This study uses an intestinal ultrasound (a safe, painless scan) to check how well Crohn's disease is controlled. It may help doctors see inflammation without more invasive tests.
AmiensAges 18 years+ - NCT07363044Recruiting
Biologic selection guided by epigenetic markers in Crohn's disease
This trial compares two different ways to choose your Crohn's treatment: one based on a special test of your cells (epigenetic markers) and the other based on standard care. It aims to see which approach works better for people with moderate to severe Crohn's disease.
AntwerpAges 18 years+ - NCT07364734Recruiting
Study of hard-to-treat Crohn's disease
This study looks at people with Crohn's disease that is hard to treat. It aims to understand the disease better and see how well current treatments work.
Guangzhou, GuangdongAges 18–65 - NCT07292012RecruitingPhase 4
Mirikizumab to heal intestinal damage in Crohn's disease
This trial tests if mirikizumab can reduce deep inflammation in the intestine walls in people with active Crohn's disease. It may help heal damage that shows up on an MRI scan.
BrestAges 18–75 - NCT07263880RecruitingPhase 1/Phase 2
Clostridium Butyricum for stricturing Crohn's disease
This trial tests a bacteria called Clostridium butyricum to see if it can help people with a type of Crohn's disease that causes narrowing in the right colon or ileocecal area. It may offer a new option for those not on strong immune-suppressing medications.
RomaAges 18–85 - NCT07196722RecruitingPhase 2/Phase 3
Testing icotrokinra for moderate to severe Crohn's disease
This study tests a new medicine called icotrokinra for people with moderate to severe Crohn's disease who have not responded well to other treatments. It aims to see if icotrokinra can help reduce symptoms and improve gut health.
Chandler, ArizonaAges 18 years+ - NCT07152431Recruiting
Using a special scan to find scar tissue in Crohn's disease
This study uses a special imaging tracer (FAPI) to find scar tissue in the small intestine of people with Crohn's disease. The goal is to see if this scan can help doctors better understand which parts of the intestine are scarred, which may guide treatment decisions.
EdinburghAges 18–90 - NCT07077746RecruitingPhase 2
Stem cells for Crohn's disease
This trial tests whether a type of stem cell called HB-adMSCs can help treat Crohn's disease. It is for adults with mild to moderate Crohn's who have certain signs of inflammation in their blood and recent imaging of their condition.
Sugar Land, TexasAges 18–65 - NCT06976853RecruitingPhase 2
Testing a new drug for Crohn’s disease beyond inflammation
This study tests a medicine called tirzepatide to see if it can help people with active Crohn’s disease who have not responded to multiple prior treatments. It focuses on how the drug might work beyond just reducing inflammation.
Beverly Hills, CaliforniaAges 18–80
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Common questions
- Are there clinical trials for crohn’s disease?
- Yes. Clin2 currently lists 333 recruiting crohn’s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a crohn’s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a crohn’s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.