Clinical trials
ctDNA clinical trials
Below are recruiting ctdna clinical trials, each written for real people, not researchers. We’re tracking 189 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06561178Recruiting
Blood Test to Monitor Esophageal Cancer After Surgery
This trial looks at whether a personalized blood test can detect cancer returning after surgery for esophageal cancer. It tests people who had chemoradiotherapy before surgery and still had some cancer remaining in the removed tissue. The goal is to use the blood test to catch any remaining or returning cancer early.
Guangzhou, GuangdongAges Any age - NCT06105177Recruiting
Using blood tests to guide lung cancer care
This trial uses a simple blood test (liquid biopsy) to find tumor DNA in people suspected of having lung cancer. The goal is to learn if this test can help doctors make better treatment decisions without needing a tissue sample.
Heerlen, LimburgAges 18 years+ - NCT07751536Recruiting
Proton radiation and intrathecal chemo for lung cancer that has spread to the brain lining
This trial tests a combination of proton radiation to the brain and spine plus chemotherapy given directly into the fluid around the brain and spinal cord. It is for people with a specific type of lung cancer (EGFR-mutant non-small cell lung cancer) that has spread to the lining of the brain and has continued to grow despite taking a third-generation TKI medicine like osimertinib.
Hefei, AnhuiAges 18–75 - NCT06589388Recruiting
Using a blood test to predict rectal cancer treatment success
This trial is looking at whether a simple blood test (ctDNA monitoring) can help predict how well total neoadjuvant therapy (chemo and radiation before surgery) works for rectal cancer. It may help doctors tailor treatment to your specific needs.
Ho Chi Minh CityAges 18–80 - NCT06609551RecruitingPhase 3
ctDNA-guided chemo choice for elderly colon cancer patients
This trial tests whether using a ctDNA blood test can help choose the best chemotherapy after colon cancer surgery for people aged 70–80. It aims to make treatment more personalized and reduce side effects.
Hangzhou, ZhejiangAges 70–80 - NCT07726602Recruiting
Tumor DNA blood test for muscle-invasive bladder cancer
This trial uses a blood test to look for small pieces of tumor DNA (ctDNA) after treatment for muscle-invasive bladder cancer. It aims to find out if the test can detect leftover or returning cancer earlier, helping guide next steps.
Portland, OregonAges 18 years+ - NCT07718841Recruiting
Blood test monitoring for early-stage breast cancer
This study uses a simple blood test called liquid biopsy to monitor cancer DNA in people with early-stage breast cancer before and during treatment. The goal is to see if this test can help guide treatment and improve outcomes.
San Sebastián, GuipúzcoaAges 18 years+ - NCT04183712RecruitingPhase 2
Targeted drug treatment after gallbladder surgery using blood test monitoring
This Phase 2 trial tests a targeted treatment (GEMOX) given after gallbladder cancer surgery. It uses a blood test that looks for cancer-related DNA to monitor recurrence and guide care, aiming to improve outcomes for people with higher-risk disease.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT02579278Recruiting
Tests blood DNA and scans in early colon cancer surgery
This study looks at a blood test that detects cancer DNA (ctDNA) and compares it with CT scan findings before surgery. It may help doctors understand how aggressive the cancer is and how scan features relate to blood test results.
Margate, KentAges 16 years+ - NCT07681323Recruiting
Timing of ctDNA Testing in Advanced Breast Cancer
This study looks at whether a simple blood test (ctDNA test) can help track advanced breast cancer over time. It aims to see how well the test works for monitoring the disease.
BeijingAges 18 years+ - NCT07660627Recruiting
ctDNA test for tracking cancer after treatment
This trial uses a blood test to find tiny bits of tumor DNA after treatment. It helps doctors see if any cancer remains, which could guide next steps for people with esophageal, stomach, or pancreatic cancer.
BrnoAges Any age - NCT05965479RecruitingPhase 2
Blood test to guide extra stomach or esophagus cancer treatment
This trial checks whether a blood test after surgery (ctDNA) can help decide if you should receive additional “adjuvant” treatment for stomach, gastroesophageal junction, or lower esophagus cancer that has HER2-positive tumors. It may help reduce the chance of cancer coming back by tailoring therapy to your risk based on the ctDNA result.
Guildford, SurreyAges 18 years+ - NCT05940311Recruiting
Blood test for melanoma with BRAF V600E mutation
This trial studies a very sensitive blood test to detect melanoma-related genetic changes in people with BRAF V600E. It may help track the disease more closely and guide care in advanced or high-risk situations.
RomeAges 18 years+ - NCT07581496Recruiting
Blood test to detect bladder cancer DNA after surgery
This study examines whether a simple blood test can detect cancer DNA (circulating tumor DNA, or ctDNA) in patients with a specific type of bladder cancer. Detecting this DNA in blood may help doctors predict how the cancer will behave and guide future treatment decisions.
BaselAges 18 years+ - NCT06242418RecruitingPhase 2
ctDNA-Guided Chemo for Stage III Colon Cancer
This trial tests whether checking for cancer DNA in your blood (ctDNA) can help doctors decide if you need extra chemotherapy after surgery for stage III colon cancer. It aims to personalize treatment and avoid unnecessary chemo.
Guiyang, GuizhouAges 18–75 - NCT07536113Recruiting
Blood Test to Guide Second Colorectal Cancer Treatment
This study looks at whether a simple blood test can help doctors decide if you should receive a specific type of cancer drug again. The blood test looks for cancer DNA to predict if the drug will work for your advanced colorectal cancer.
Milan, ItaliaAges 18 years+ - NCT06755619Recruiting
ctDNA testing for response in first-line PCNSL treatment
This study tests whether a blood test (ctDNA) can help doctors see how well treatment is working for people with a type of brain lymphoma (PCNSL) who are getting their first treatment with a cure in mind.
HelsinkiAges 18–70 - NCT07516678Recruiting
Blood Tests to Track Neuroblastoma During Treatment
This study collects blood samples from neuroblastoma patients to test for tiny pieces of tumor DNA that can show how well treatment is working. By tracking these markers over time, doctors hope to better predict how patients will respond and improve care.
Guangzhou, GuangdongAges Any age - NCT07517107RecruitingPhase 2
Blood tests to guide gastric cancer treatment decisions
This study uses special blood tests to detect cancer DNA and help doctors decide the best treatment plan for gastric cancer. The goal is to improve outcomes by personalizing therapy based on how your cancer responds.
ShanghaiAges 18 years+ - NCT06230185Recruiting
Blood test to monitor treatment response in triple-negative breast cancer
This trial is testing whether a blood test can track how well chemotherapy is working in people with early-stage triple-negative breast cancer. You would provide blood samples before and during treatment, and the results may help your doctor understand your response better.
Tucson, ArizonaAges 18 years+ - NCT07504796RecruitingPhase 2
Adding ipilimumab to standard melanoma therapy based on ctDNA
This trial tests whether adding a second immunotherapy drug (ipilimumab) to the standard first-line combo of nivolumab and relatlimab improves outcomes for advanced melanoma. It uses a blood test (ctDNA) to decide who gets the extra drug.
New York, New YorkAges 18 years+ - NCT07491328Recruiting
Liquid biopsy for nerve disorders linked to cancer
This study uses a blood test (liquid biopsy) to look for cancer-related signals in people with certain nerve disorders caused by the immune system (paraneoplastic neurological syndromes) or in people with tumors that do not affect the nerves. It aims to better understand and detect these conditions.
DüsseldorfAges 18 years+ - NCT04846933Recruiting
Testing extra scans and data to guide ovarian cancer treatment
This trial collects information from people with suspected ovarian cancer and uses it to improve diagnosis and help predict which treatments may work. It may also look for targeted options, based on scan and medical data results.
TurkuAges 18 years+ - NCT07459673RecruitingPhase 2
HER2-positive breast cancer trial using ctDNA to guide treatment
This trial tests a personalized treatment plan for HER2-positive breast cancer that has spread. It uses a blood test to track cancer DNA and adjust therapy, including treatments that may help prevent cancer from reaching the brain. The goal is to achieve long-term remission.
Basking Ridge, New JerseyAges 18 years+
Hear when a new ctDNA trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for ctdna?
- Yes. Clin2 currently lists 189 recruiting ctdna studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ctdna trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ctdna trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.