Clin2
NCT07459673Possibly a fitRecruiting

HER2-positive breast cancer trial using ctDNA to guide treatment

Breast CancerHER2-positive Breast CancerBreast Cancer Stage IV

Treatments studied

Part of Cancer, Skin clinical trials.

This trial tests a personalized treatment plan for HER2-positive breast cancer that has spread. It uses a blood test to track cancer DNA and adjust therapy, including treatments that may help prevent cancer from reaching the brain. The goal is to achieve long-term remission.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
60 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 or older with HER2-positive (3+ score) breast cancer that has spread to other parts of the body or cannot be removed by surgery.
  • Your cancer must be stage IV when first diagnosed, meaning it has spread at diagnosis.
  • You should be healthy enough for surgery, or likely to become operable after initial treatment.
  • You must have not received any prior anti-HER2 therapy or other cancer treatment for breast cancer.
  • Your overall health status must be good (ECOG score 0 or 1), and your organs must work well (blood counts, liver, kidney function within limits).
  • If you can become pregnant or get someone pregnant, you must agree to use effective contraception during and after the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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