Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,560 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07449325Recruiting
Heart sinus reducer for chest pain from small vessel disease
This trial tests a device placed in a heart vein (the coronary sinus) to improve blood flow and reduce chest pain in people with coronary microvascular dysfunction (small blood vessel disease). It aims to help those who still have symptoms despite taking heart medications.
New Haven, ConnecticutAges 18 years+ - NCT03167437RecruitingPhase 1/Phase 2
Vorinostat for uncontrolled Crohn’s or ulcerative colitis
This early-phase study tests vorinostat to reduce gut inflammation in people with moderate-to-severe Crohn’s disease, ulcerative colitis, or certain colitis patterns linked to chronic granulomatous disease (CGD). It also looks at whether the study’s consent process is clear and understood before starting treatment.
Bethesda, MarylandAges 18–65 - NCT03174938Recruiting
BioFINDER 2 study for healthy aging and memory problems
This study uses brain scans and a spinal fluid test to better understand memory and thinking changes in different groups, from people with healthy thinking to early or established dementia. If you qualify, it may help researchers learn what’s driving these conditions and how they progress.
ÄngelholmAges 20–100 - NCT03374215Recruiting
Study hormone causes of high blood pressure in Black adults
This study looks at the body’s hormone signals to understand what causes primary aldosteronism (a condition that can lead to high blood pressure). By comparing clinical results and lab data, researchers hope to improve how the condition is diagnosed and managed, especially in Black participants.
Bethesda, MarylandAges 7–70 - NCT03402919Recruiting
Brain and memory study for people with thinking changes
This study looks at memory and thinking changes using questionnaires, memory testing, and brain scans. It may help researchers better understand neurodegeneration and dementia and how these problems show up over time.
Calgary, AlbertaAges 50–90 - NCT03510442Recruiting
Study of joint illness patterns and genes in juvenile and adult diseases
This study follows people with systemic juvenile idiopathic arthritis (sJIA), adult-onset Still’s disease (AOSD), and similar conditions to learn how the illness works over time. It also collects blood and family information to study genetics and explain what causes flare-ups, which may help future care.
Bethesda, MarylandAges 1 day–100 years - NCT03589183Recruiting
Gut microbiome study for ulcerative colitis and Crohn disease
This study looks at how changes in gut bacteria (the microbiome) relate to inflammatory bowel disease, including ulcerative colitis and Crohn disease. It may help researchers understand what might improve symptoms or disease control.
SeoulAges Any age - NCT03621839Recruiting
Study of new spinal-fluid tests for Alzheimer’s disease
This study looks at new test markers found in spinal fluid to help with diagnosing Alzheimer’s disease. If you are already getting a spinal-fluid sample as part of your dementia workup, this trial may check it for additional information.
Nancy, Grand EstAges Any age - NCT03678194Recruiting
Smartphone app tool for doctors managing daily depression
This trial tests a smartphone app that helps doctors manage depression in everyday life. It may help improve how care is tracked and adjusted soon after starting antidepressant treatment.
BordeauxAges 18–65 - NCT03713203Recruiting
Light-based treatment for vulvar Paget’s disease
This study tests a special light treatment (photodynamic therapy) for non-invasive Paget’s disease on the vulva that has come back after surgery. It may help by treating remaining abnormal skin cells where surgery may not remove everything.
LilleAges 18 years+ - NCT03717844Recruiting
Registry for adults with plasma cell disorders
This study is a registry that collects information about adults with plasma cell disorders (conditions involving abnormal antibody-producing cells). It may help researchers understand these diseases better and improve future care by tracking patients over time.
Chapel Hill, North CarolinaAges 18 years+ - NCT03799991Recruiting
Balance therapy for people with early-to-moderate Alzheimer’s
This trial tests whether an 8-week balance and movement program can help people with early-to-moderate Alzheimer’s who also have inner-ear (vestibular) balance loss. You and a caregiver may learn exercises and attend weekly visits, while researchers compare the results to an active control program.
Baltimore, MarylandAges 60 years+ - NCT03809728Recruiting
Finding blood tests linked to outcomes in Crohn’s and colitis
This study looks for “biomarkers” (lab markers, like substances in blood or tissue) that may predict how Crohn’s disease or ulcerative colitis will go and how patients may respond. It may help doctors choose better monitoring or treatments in the future.
Vandœuvre-lès-NancyAges 18 years+ - NCT03816345RecruitingPhase 1
Nivolumab for advanced cancer with autoimmune conditions
This Phase 1 study tests nivolumab, an immunotherapy “anti-cancer accelerator,” in people with advanced cancer who also have an autoimmune disorder. It aims to see if nivolumab can be given safely and whether it may help shrink or control cancer.
Birmingham, AlabamaAges 18 years+ - NCT03869554Recruiting
Screening for Fabry disease in people with kidney biopsy results
This study tests a screening approach to find Fabry disease in adults whose kidney biopsy findings are unclear or suggest certain kidney patterns. If Fabry disease is missed, it can delay targeted treatment, so screening may help identify people who could benefit from earlier care.
AngersAges 18 years+ - NCT07700342Recruiting
Could an evening gel improve sleep for nighttime reflux?
This trial tests a topical therapy you apply at night to see if it can improve sleep for people with non-erosive GERD who still have nighttime symptoms even while taking a morning acid reducer.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT07703683Recruiting
Muscle health in metabolic and hormone diseases
This trial looks at how muscle health is affected by metabolic or hormone disorders, aiming to find better markers for muscle loss called sarcopenia.
Woluwe-Saint-Pierre - Sint-Pieters-WoluweAges 18 years+ - NCT04024774Recruiting
Genetic testing study for rare diseases with an unclear cause
This study looks for a genetic (DNA) explanation for rare diseases when usual genetic testing hasn’t found an answer. It may help by re-analyzing prior results and comparing them with parents’ DNA to better pinpoint the cause.
DijonAges Any age - NCT04039763Recruiting
Glucose monitoring for young adults at risk of DKA
This study tests a real-time glucose monitor (RT-CGM) to help young adults with insulin-treated diabetes recognize dangerously high or fast-changing blood sugars. It may help lower the risk of diabetic ketoacidosis (DKA), a serious complication that can lead to urgent care or hospital stays.
LondonAges 18–25 - NCT04061967Recruiting
Reminder and self-sampling to help cervical screening
This study tests whether reminders and providing an at-home sample kit can help more women complete cervical cancer screening. It may help people who have not had follow-up after a prior abnormal result or who haven’t been screened in many years.
Luleå, Norrbotten CountyAges 33–75 - NCT04079179RecruitingPhase 2
Cobimetinib for difficult Langerhans cell and similar disorders
This Phase 2 trial studies cobimetinib, a medicine that targets a specific growth-and-signal pathway, to treat stubborn (refractory or worsening) Langerhans cell histiocytosis and related disorders. It may help shrink active disease or stop disease from progressing.
Phoenix, ArizonaAges Any age - NCT04095351Recruiting
Study of connective tissue disease affecting the lungs
This study looks at people aged 18 and older who have a connective tissue disease and lung involvement. It aims to better understand how these lung problems progress and may help doctors choose better care.
InnsbruckAges 18–80 - NCT04101968Recruiting
Study of GBA changes in Parkinson’s using multiple tests
This study looks at people with Parkinson’s who carry a specific genetic change in the GBA gene. It uses several tests (including brain scans) to understand the disease better and may help guide future treatments.
Portland, OregonAges 18–80 - NCT04185844Recruiting
Chronic kidney health study for Native American adults
This study follows Native American adults with kidney function changes (either moderately reduced kidney filtration or early urine protein). It aims to better understand kidney disease over time and what factors predict progress, which may help improve care for people like you.
Phoenix, ArizonaAges 21–80
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,560 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.