Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,350 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05921162Enrolling by invitation
Long-term follow-up after a vision gene eye injection
This study checks how people who previously received a gene therapy eye injection (vMCO-I) are doing over the long term. It may help researchers understand long-lasting effects and safety.
Cuttack, OdishaAges 18 years+ - NCT05934747Recruiting
Parkinson’s trial for people with implanted brain stimulators
This study tests an approach to improving Parkinson’s symptoms in people who already have deep brain stimulation (DBS) devices. It focuses on patients who are able to do walking tests safely and confirm they can understand and consent.
Minneapolis, MinnesotaAges 18–85 - NCT05925621Recruiting
Registry for early Alzheimer-related memory problems
This study registry collects health and brain-testing information for people with mild cognitive impairment or early Alzheimer’s dementia. It may help researchers better understand early Alzheimer disease and plan future treatments.
Boston, MassachusettsAges 50–95 - NCT05919056Recruiting
Check heart disease risk and monitor changes over time
This study helps test a prevention plan for people who are at higher risk of heart disease. It uses regular monitoring to see if early prevention can reduce risk before heart problems happen.
Ningbo, ZhejiangAges 40–79 - NCT05912387RecruitingEarly Phase 1
Testing statin treatment in primary sclerosing cholangitis
This early study looks at how a statin (cholesterol-lowering medicine) affects people with primary sclerosing cholangitis (PSC) by measuring changes using multiple types of health data. It may help researchers understand which people benefit and how PSC biology changes with treatment.
Stanford, CaliforniaAges 18–80 - NCT05927090Enrolling by invitation
Repair outcomes after acute aortic dissection surgery
This study looks at how patients do after surgery for an urgent (acute) tear of the aorta or related bleeding in the wall of the ascending aorta. It may help doctors better understand what outcomes to expect after early emergency surgery.
Saint-DenisAges 18–90 - NCT05929703Recruiting
Caring for hospitalized older adults
This study tests a new approach to caring for older adults in the hospital to prevent confusion (delirium). It involves having a family member or care partner stay with the patient during the hospital stay.
Orange, CaliforniaAges 70 years+ - NCT05919160Enrolling by invitation
New tiny electrode to record brain activity during DBS
This study tests a high-density microelectrode that captures detailed brain recordings while surgeons place a deep brain stimulator for Parkinson’s disease. It may help doctors better locate the exact brain area to target during surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT05923489Recruiting
Follow-up angiography after stent placement in high-risk patients
This study checks how routine repeat heart blood-vessel imaging (angiography) after stent placement may help high-risk patients. It is meant for people who had a successful stent procedure and have certain higher-risk heart features.
Hangzhou, ZhejiangAges 18 years+ - NCT05934565Recruiting
Using mindfulness coaching to help people move more
This trial studies a program that uses mindfulness coaching to help people with chronic lung disease (COPD) and/or heart failure (HF) be more physically active. You may benefit if you can safely start exercising and track your steps using a Fitbit.
Boston, MassachusettsAges 40 years+ - NCT05928169Recruiting
Tracking how inflammatory skin conditions change over time
This study looks at what affects the “path” (trajectory) of long-lasting inflammatory skin conditions. It may help researchers understand why symptoms change and how treatments or factors influence those changes.
KielAges birth–80 years - NCT05916469Recruiting
Hormone treatment for heavy periods in teens and young adults
This trial studies how a progestin hormone—given as an IUD or tablets—can help reduce heavy menstrual bleeding in people with certain bleeding-related conditions. It may help you by testing whether the treatment works and is practical for your situation.
Palo Alto, CaliforniaAges 10–24 - NCT05932017Enrolling by invitation
Compare two ways to see during gum surgery
This trial compares two tools surgeons use to see during gum (periodontal) surgery: magnifying loupes versus a videoscope. It may help improve how the procedure is done for people with more severe gum disease.
Dallas, TexasAges 18 years+ - NCT05913843Recruiting
Study how ancestry may affect facial features in rare genetic conditions
This study looks at how a person’s ancestry might influence the facial appearance seen in rare inherited (genetic) diseases. You may be considered if you have unusual physical signs and doctors suspect a genetic cause.
TaipeiAges Any age - NCT05361980Recruiting
Study of safety and results of a pediatric bone implant
This study looks at whether a specific pediatric bone implant is safe and works well for children who need it. By joining, you help researchers track outcomes over time and understand possible implant-related side effects.
Vancouver, British ColumbiaAges birth–25 years - NCT05768178RecruitingPhase 2/Phase 3
Vemurafenib plus cobimetinib for BRAF-mutant cancers
This trial tests whether combining two targeted cancer medicines—vemurafenib and cobimetinib—can treat adults whose tumors have a specific “BRAF V600” mutation. You may be screened with blood tests and a tissue biopsy before starting treatment.
BelfastAges 18 years+ - NCT05733520Recruiting
Telehealth coaching for Alzheimer’s caregivers using a phone
This trial tests a mobile telehealth program designed to help unpaid caregivers reduce Alzheimer’s-related symptoms in the people they care for. If you’re a primary caregiver, you may get study sessions using a smartphone or similar device.
Indianapolis, IndianaAges 18 years+ - NCT05738330Recruiting
Symptom reporting during hemodialysis care
This study looks at how well a new phone or computer system can help people on hemodialysis report their symptoms. It may improve symptom tracking so clinics can better understand and respond to what you feel during treatment.
Waltham, MassachusettsAges 18 years+ - NCT05785637Recruiting
Home sleep testing after starting noninvasive breathing support
This study checks breathing/sleep measurements done at home for people who recently started a machine that helps them breathe without an endotracheal tube. It may help the team confirm how well home monitoring works after hospital setup of this breathing support.
GarchesAges 18 years+ - NCT05907759RecruitingPhase 2
Daratumumab for HIV-related lymphomas and Castleman disease
This trial tests a drug called daratumumab for people with certain HIV-related blood cancers (primary effusion lymphoma, plasmablastic lymphoma) or a related condition called multicentric Castleman disease that has come back or not improved after standard treatment. The drug targets a protein on cancer cells to help the immune system attack them. It might be a new option when standard chemotherapy isn't working or isn't suitable.
Bethesda, MarylandAges 18–120 - NCT05886049RecruitingPhase 1
Testing a menin drug with standard chemo for newly diagnosed AML
This early-phase study tests a menin inhibitor drug (SNDX-5613) combined with standard induction chemotherapy (daunorubicin plus cytarabine) in newly diagnosed AML with specific gene changes (NPM1 or FLT3 status, or MLL/KMT2A or NUP98). It may help patients whose AML has these genetic features respond better to intensive treatment.
Orange, CaliforniaAges 18–75 - NCT05881005Recruiting
NAC for fatty liver in people with active Cushing’s
This study tests whether NAC (a supplement/medicine) can improve liver health in adults who have active Cushing’s syndrome and fatty liver disease. It may help if your excess stress hormone levels are affecting your liver.
AngersAges 18 years+ - NCT05893186RecruitingEarly Phase 1
Testing DBS settings for walking and balance in Parkinson’s
This early-phase study looks at whether adjusting deep brain stimulation (DBS) can improve posture, walking, and balance in people with Parkinson’s disease. If you already have DBS in place, the trial uses computer-based planning to try different DBS directions and settings to see what helps you most.
Minneapolis, MinnesotaAges 18–89 - NCT05888935Recruiting
AI checks for tooth root infections on dental X-rays
This study tests an artificial intelligence tool to detect small infections around tooth roots using routine panoramic dental X-rays. You might benefit if your scans are used to more accurately spot these problems compared with standard reading.
MetzAges 18 years+
Hear when a new Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,350 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.