Clinical trials
Eosinophilic Esophagitis clinical trials
Below are recruiting eosinophilic esophagitis clinical trials, each written for real people, not researchers. We’re tracking 36 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07112378RecruitingPhase 3
Study of dupilumab for young children with eosinophilic esophagitis
This trial tests if dupilumab can help young children with eosinophilic esophagitis (EoE), a condition that causes swelling in the esophagus. It may reduce symptoms and improve how the esophagus heals.
Phoenix, ArizonaAges 6 months–6 years - NCT07708467Enrolling by invitation
Esophageal function study in eosinophilic esophagitis
This study looks at how the esophagus stretches and moves in people with eosinophilic esophagitis (EoE) who still have symptoms even though their inflammation is under control. The goal is to better understand why symptoms persist and find better ways to measure them.
Milan, MIAges 18 years+ - NCT05199532Recruiting
Eosinophilic gut condition registry for children
This study builds a registry of children with eosinophilic gastrointestinal (gut) disorders (EGIDs) and also includes children being evaluated for possible EGIDs. It may help doctors better understand these conditions and improve future care.
Chicago, IllinoisAges 1–25 - NCT05730933Recruiting
Study to help adults stick to eosinophilic esophagitis treatment
This trial tests an intervention meant to improve how well adults with eosinophilic esophagitis (EoE) follow their ongoing treatment plan. It may help you stay on your medicine and get better symptom control by making adherence easier.
AmsterdamAges 18 years+ - NCT06093204Recruiting
Ultra-processed foods and eosinophilic esophagitis study
This study looks at how certain chemicals from ultra-processed foods (like packaged snacks and sodas) might trigger eosinophilic esophagitis, a food allergy condition. It will compare people with the disease to healthy volunteers of the same age and sex.
NaplesAges 3–65 - NCT06387030Recruiting
EoE biopsy study during endoscopy
This trial looks at taking a small tissue sample during a routine endoscopy to better understand eosinophilic esophagitis (EoE). It may help doctors learn how to diagnose and track EoE more easily.
ParisAges 2–17 - NCT06389994Recruiting
String test to monitor esophagus health during allergy treatment
This study tests a new way to check for a condition called eosinophilic esophagitis (EoE) in children getting oral immunotherapy for food allergies. You swallow a small capsule on a string to collect cells from your esophagus—no endoscopy needed.
Philadelphia, PennsylvaniaAges 7–17 - NCT06443346Recruiting
Registry for people with eosinophilic esophagitis
This is a registry (like a medical diary) for people with EoE who are getting regular treatment. It helps doctors track how EoE affects people over time, so they can improve care for everyone.
Milan, LombardyAges Any age - NCT06817213Recruiting
Decision support for eosinophilic esophagitis (EoE) patients
This study tests a decision aid (a simple tool) to help adults with EoE make choices about their care. You may be able to join if you are a new EoE patient at the University of Michigan, are 18 or older, speak English, and have internet access.
Ann Arbor, MichiganAges 18 years+ - NCT06972147Recruiting
Food-induced esophagus symptoms in kids with EoE
This study looks at how often children with eosinophilic esophagitis (a type of food allergy causing esophagus swelling) have immediate symptoms after eating certain foods. It may help doctors better understand and manage the condition.
AngersAges 6–17 - NCT07234825Recruiting
Trial of dairy-free diet with liquid nutrition for eosinophilic esophagitis
This study tests whether a dairy-free diet combined with a special liquid nutrition drink (called Kate Farms) can help children and young adults with eosinophilic esophagitis (a condition where certain white blood cells build up in the esophagus and cause trouble swallowing, pain, or vomiting). The goal is to see if this combination can reduce symptoms and improve quality of life.
Seattle, WashingtonAges 1–21 - NCT02523118Recruiting
Measuring symptoms and test results in eosinophilic gut diseases
This study looks at how eosinophilic inflammation in the esophagus and intestines affects outcomes like symptoms and test findings. It may help clinicians better understand these conditions and track what changes over time.
Phoenix, ArizonaAges 3 years+ - NCT07358234Enrolling by invitationEarly Phase 1
Comparing two EoE treatments on esophagus widening
This study compares two medicines—Eohilia (an oral steroid) and Dupixent (an injectable biologic)—to see which one better helps widen the esophagus in people with eosinophilic esophagitis (EoE). It may help you if you have active EoE and are looking for a new treatment option.
Scottsdale, ArizonaAges 18 years+ - NCT03980886Recruiting
Study of inflammation in children with eosinophilic esophagitis
This study looks at how inflamed the esophagus is in children who have eosinophilic esophagitis (EoE). It may help doctors better understand what’s driving symptoms like trouble swallowing and food getting stuck.
San Diego, CaliforniaAges 1–65 - NCT05219903Recruiting
Study of children with eosinophilic gut disorders
This study looks at children ages 0–18 with eosinophilic gut disorders (EGIDs) to better understand these conditions and how they are managed. It may help doctors improve care by comparing real-world information from patients followed at participating hospitals.
PaviaAges birth–18 years - NCT05608681RecruitingPhase 1/Phase 2
Study drug for adults with eosinophilic esophagitis (EoE
This Phase 1/2 study tests EP-104GI in adults with eosinophilic esophagitis (EoE), a condition where certain immune cells cause inflammation in the food pipe. It may help improve symptoms and inflammation, and the study also includes a part where people who do well can switch to the active drug.
Sydney, New South WalesAges 18–75 - NCT06665971RecruitingPhase 4
Dupilumab for esophagus muscle function in EoE
This trial tests if dupilumab, a weekly injection, can improve the muscle function of the esophagus in people with eosinophilic esophagitis (EoE) who haven't gotten better with acid-reducing medications. Researchers want to see if it helps with swallowing and reduces inflammation.
La Jolla, CaliforniaAges 22 years+ - NCT05485155RecruitingPhase 2
Zemaira trial for adults with eosinophilic esophagus
This Phase 2 study tests Zemaira (an alpha-1 antitrypsin treatment given through an IV) to see if it improves eosinophilic esophagitis (EoE) in adults. You may be able to help researchers learn whether this treatment can reduce EoE activity when standard treatments haven’t worked.
Bethesda, MarylandAges 18–70 - NCT07027826Recruiting
String test for eosinophilic esophagitis in African patients
This study tests a new, less invasive way (the Esophageal String Test) to look for signs of eosinophilic esophagitis—an allergic condition that can make swallowing painful or difficult. It is for people of African descent who have trouble swallowing and are already having an endoscopy.
Bethesda, MarylandAges 18–65 - NCT06991881Recruiting
Better management for eosinophilic esophagitis
This study looks at how to improve care for people with eosinophilic esophagitis (EoE), a condition that causes inflammation in the esophagus. It may help you if you have or are being checked for EoE.
BergenAges Up to 17 years - NCT07614633Recruiting
Understanding Eosinophilic Esophagitis Over Time
This study follows patients with eosinophilic esophagitis (a condition where too many white blood cells called eosinophils build up in the food tube) to understand how the disease changes over time and what happens with different treatments. By tracking your symptoms and test results, doctors hope to learn how to better manage this condition.
Pavia, PaviaAges 5 years+ - NCT07227506Recruiting
Mucosal impedance testing for chronic esophagus issues
This trial uses a special device during an upper endoscopy to measure the electrical properties of the esophagus lining, which may help diagnose chronic reflux or swallowing problems.
Milwaukee, WisconsinAges 18 years+ - NCT05180578Recruiting
Goat milk protein study for children with milk-triggered esophagus inflammation
This trial tests whether goat milk protein is tolerated and safe for kids with eosinophilic esophagitis (EoE) whose symptoms improve when cow milk is stopped and come back when cow milk is added again. It may help some families find an alternative to cow milk, but you must meet specific “milk trigger” and allergy-safety requirements.
JerusalemAges Up to 18 years - NCT06756581Enrolling by invitation
Baked dairy trial for children with eosinophilic esophagitis
This trial tests whether children with eosinophilic esophagitis triggered by cow's milk can safely eat baked dairy foods. If you are in remission on a milk-free diet, you may be able to add baked milk products back into your diet.
JerusalemAges Up to 18 years
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Eosinophilic Esophagitis trials by city
Studies with a site in or near these metro areas.
Eosinophilic Esophagitis trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for eosinophilic esophagitis?
- Yes. Clin2 currently lists 36 recruiting eosinophilic esophagitis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a eosinophilic esophagitis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a eosinophilic esophagitis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.