Study drug for adults with eosinophilic esophagitis (EoE
Part of Blood & lymphatic, Digestive system, Immune system & allergy clinical trials.
This Phase 1/2 study tests EP-104GI in adults with eosinophilic esophagitis (EoE), a condition where certain immune cells cause inflammation in the food pipe. It may help improve symptoms and inflammation, and the study also includes a part where people who do well can switch to the active drug.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have EoE symptoms now (a diagnosed EoE condition, not just reflux).
- You can attend all study visits and follow study instructions exactly as scheduled.
- You are able and willing to sign informed consent (agree to take part after learning the risks).
- If you could become pregnant: you must have a negative pregnancy test and use very effective birth control during the entire study.
- You must be able to safely have procedures like an endoscopy and biopsies (small tissue samples from the esophagus).
- You do not have other conditions or infections that could interfere with the study or increase risk.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests an intervention meant to improve how well adults with eosinophilic esophagitis (EoE) follow their ongoing treatment plan. It may help you stay on your medicine and get better symptom control by making adherence easier.
This study looks at how eosinophilic inflammation in the esophagus and intestines affects outcomes like symptoms and test findings. It may help clinicians better understand these conditions and track what changes over time.
This study looks at how inflamed the esophagus is in children who have eosinophilic esophagitis (EoE). It may help doctors better understand what’s driving symptoms like trouble swallowing and food getting stuck.
This trial looks at taking a small tissue sample during a routine endoscopy to better understand eosinophilic esophagitis (EoE). It may help doctors learn how to diagnose and track EoE more easily.
This pilot study looks at how proton pump inhibitor medicines (acid reducers) change the flexibility of the esophagus in people who have eosinophilia on esophagus biopsy. It may help doctors understand whether acid control could improve esophagus function in this condition.
This study looks at children ages 0–18 with eosinophilic gut disorders (EGIDs) to better understand these conditions and how they are managed. It may help doctors improve care by comparing real-world information from patients followed at participating hospitals.
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