Clinical trials
Eosinophilic Esophagitis (EoE) clinical trials
Below are recruiting eosinophilic esophagitis (eoe) clinical trials, each written for real people, not researchers. We’re tracking 24 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07112378RecruitingPhase 3
Study of dupilumab for young children with eosinophilic esophagitis
This trial tests if dupilumab can help young children with eosinophilic esophagitis (EoE), a condition that causes swelling in the esophagus. It may reduce symptoms and improve how the esophagus heals.
Phoenix, ArizonaAges 6 months–6 years - NCT07708467Enrolling by invitation
Esophageal function study in eosinophilic esophagitis
This study looks at how the esophagus stretches and moves in people with eosinophilic esophagitis (EoE) who still have symptoms even though their inflammation is under control. The goal is to better understand why symptoms persist and find better ways to measure them.
Milan, MIAges 18 years+ - NCT03980886Recruiting
Study of inflammation in children with eosinophilic esophagitis
This study looks at how inflamed the esophagus is in children who have eosinophilic esophagitis (EoE). It may help doctors better understand what’s driving symptoms like trouble swallowing and food getting stuck.
San Diego, CaliforniaAges 1–65 - NCT05608681RecruitingPhase 1/Phase 2
Study drug for adults with eosinophilic esophagitis (EoE
This Phase 1/2 study tests EP-104GI in adults with eosinophilic esophagitis (EoE), a condition where certain immune cells cause inflammation in the food pipe. It may help improve symptoms and inflammation, and the study also includes a part where people who do well can switch to the active drug.
Sydney, New South WalesAges 18–75 - NCT05730933Recruiting
Study to help adults stick to eosinophilic esophagitis treatment
This trial tests an intervention meant to improve how well adults with eosinophilic esophagitis (EoE) follow their ongoing treatment plan. It may help you stay on your medicine and get better symptom control by making adherence easier.
AmsterdamAges 18 years+ - NCT06389994Recruiting
String test to monitor esophagus health during allergy treatment
This study tests a new way to check for a condition called eosinophilic esophagitis (EoE) in children getting oral immunotherapy for food allergies. You swallow a small capsule on a string to collect cells from your esophagus—no endoscopy needed.
Philadelphia, PennsylvaniaAges 7–17 - NCT06443346Recruiting
Registry for people with eosinophilic esophagitis
This is a registry (like a medical diary) for people with EoE who are getting regular treatment. It helps doctors track how EoE affects people over time, so they can improve care for everyone.
Milan, LombardyAges Any age - NCT06665971RecruitingPhase 4
Dupilumab for esophagus muscle function in EoE
This trial tests if dupilumab, a weekly injection, can improve the muscle function of the esophagus in people with eosinophilic esophagitis (EoE) who haven't gotten better with acid-reducing medications. Researchers want to see if it helps with swallowing and reduces inflammation.
La Jolla, CaliforniaAges 22 years+ - NCT06817213Recruiting
Decision support for eosinophilic esophagitis (EoE) patients
This study tests a decision aid (a simple tool) to help adults with EoE make choices about their care. You may be able to join if you are a new EoE patient at the University of Michigan, are 18 or older, speak English, and have internet access.
Ann Arbor, MichiganAges 18 years+ - NCT07012928Recruiting
Study of immune responses in eosinophilic esophagitis patients
This study looks at how the immune system and the esophageal barrier function in people with eosinophilic esophagitis (EoE) compared to those without. It involves taking biopsies during an upper endoscopy to understand the disease better. The results may help improve treatments for EoE.
Amsterdam, North HollandAges 18–75 - NCT07234825Recruiting
Trial of dairy-free diet with liquid nutrition for eosinophilic esophagitis
This study tests whether a dairy-free diet combined with a special liquid nutrition drink (called Kate Farms) can help children and young adults with eosinophilic esophagitis (a condition where certain white blood cells build up in the esophagus and cause trouble swallowing, pain, or vomiting). The goal is to see if this combination can reduce symptoms and improve quality of life.
Seattle, WashingtonAges 1–21 - NCT02523118Recruiting
Measuring symptoms and test results in eosinophilic gut diseases
This study looks at how eosinophilic inflammation in the esophagus and intestines affects outcomes like symptoms and test findings. It may help clinicians better understand these conditions and track what changes over time.
Phoenix, ArizonaAges 3 years+ - NCT07614633Recruiting
Understanding Eosinophilic Esophagitis Over Time
This study follows patients with eosinophilic esophagitis (a condition where too many white blood cells called eosinophils build up in the food tube) to understand how the disease changes over time and what happens with different treatments. By tracking your symptoms and test results, doctors hope to learn how to better manage this condition.
Pavia, PaviaAges 5 years+ - NCT07358234Enrolling by invitationEarly Phase 1
Comparing two EoE treatments on esophagus widening
This study compares two medicines—Eohilia (an oral steroid) and Dupixent (an injectable biologic)—to see which one better helps widen the esophagus in people with eosinophilic esophagitis (EoE). It may help you if you have active EoE and are looking for a new treatment option.
Scottsdale, ArizonaAges 18 years+ - NCT06756581Enrolling by invitation
Baked dairy trial for children with eosinophilic esophagitis
This trial tests whether children with eosinophilic esophagitis triggered by cow's milk can safely eat baked dairy foods. If you are in remission on a milk-free diet, you may be able to add baked milk products back into your diet.
JerusalemAges Up to 18 years - NCT05219903Recruiting
Study of children with eosinophilic gut disorders
This study looks at children ages 0–18 with eosinophilic gut disorders (EGIDs) to better understand these conditions and how they are managed. It may help doctors improve care by comparing real-world information from patients followed at participating hospitals.
PaviaAges birth–18 years - NCT06381219Recruiting
Heating milk or egg for kids with EoE
This study tests whether heating cow's milk or hen's egg (like baking them) can help children with EoE stay in remission. It's for children whose EoE is triggered by these foods and who are currently doing well (no active EoE).
Leuven, Vlaams-BrabantAges 1–18 - NCT05485155RecruitingPhase 2
Zemaira trial for adults with eosinophilic esophagus
This Phase 2 study tests Zemaira (an alpha-1 antitrypsin treatment given through an IV) to see if it improves eosinophilic esophagitis (EoE) in adults. You may be able to help researchers learn whether this treatment can reduce EoE activity when standard treatments haven’t worked.
Bethesda, MarylandAges 18–70 - NCT06596252RecruitingPhase 3
Budesonide Once vs Twice Daily for EoE Remission
This study tests whether a budesonide tablet that dissolves in the mouth works as well when taken once a day compared to twice a day for treating active eosinophilic esophagitis (EoE). It aims to help people with EoE achieve remission (feeling better and less inflammation).
Scottsdale, ArizonaAges 18–75 - NCT06705387RecruitingPhase 2
Dupilumab vs steroid for narrow EoE in young people
This study compares two treatments for EoE that has caused narrowing in the esophagus: dupilumab (a biologic injection) versus a topical corticosteroid (a swallowed steroid). It aims to see which works better for teens and young adults to improve swallowing and reduce inflammation.
Aurora, ColoradoAges 12–25 - NCT05180578Recruiting
Goat milk protein study for children with milk-triggered esophagus inflammation
This trial tests whether goat milk protein is tolerated and safe for kids with eosinophilic esophagitis (EoE) whose symptoms improve when cow milk is stopped and come back when cow milk is added again. It may help some families find an alternative to cow milk, but you must meet specific “milk trigger” and allergy-safety requirements.
JerusalemAges Up to 18 years - NCT06695897Recruiting
Long-term real-world study of Dupilumab for eosinophilic esophagitis
This study looks at how well Dupilumab works over time in people aged 12 and older with eosinophilic esophagitis (EoE) whose symptoms are not well controlled by standard treatments. It aims to understand the medicine's effects in everyday medical practice.
Dachau, BavariaAges 12 years+ - NCT07506746Recruiting
Study on esophagus movement
This study tracks patients with reflux, swallowing problems, or other esophageal symptoms to understand how the esophagus moves. It may help if you have heartburn, regurgitation, or related issues like cough or chest pain.
Milan, LombardyAges 18 years+ - NCT02504853Recruiting
Study food allergy patterns and genetics over time
This study follows people with food allergy and some closely related or healthy people to learn how food allergy (and related conditions) develops over time. It may help researchers find causes and better ways to predict and treat food allergy.
Bethesda, MarylandAges 1 day–99 years
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Eosinophilic Esophagitis (EoE) trials by city
Studies with a site in or near these metro areas.
Eosinophilic Esophagitis (EoE) trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for eosinophilic esophagitis (eoe)?
- Yes. Clin2 currently lists 24 recruiting eosinophilic esophagitis (eoe) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a eosinophilic esophagitis (eoe) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a eosinophilic esophagitis (eoe) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.