Clinical trials
Eye Diseases clinical trials
Below are recruiting eye diseases clinical trials, each written for real people, not researchers. We’re tracking 181 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07257185RecruitingPhase 3
MHB018A for Chronic Thyroid Eye Disease
This study tests a new medication called MHB018A for people with chronic Thyroid Eye Disease (TED) that is moderate to severe. It aims to see if the drug can help improve symptoms and quality of life over time.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07262476RecruitingPhase 3
Extension study of MHB018A for thyroid eye disease
This study tests a longer-term use of MHB018A for people with thyroid eye disease who did not fully respond to treatment in a previous study. It aims to see if further treatment can help improve eye bulging and other symptoms.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07363824Recruiting
Tear iron and dry eye severity study
This study looks at how iron levels in tears relate to the severity of dry eye disease. It aims to find a simple way to measure dry eye severity, which could help doctors better understand and treat the condition.
ShanghaiAges 18–70 - NCT07400757Recruiting
Statin and vitamin D for active thyroid eye disease
This trial tests whether a statin (a cholesterol-lowering medicine) combined with vitamin D can improve active thyroid eye disease. It may help if you have both eye inflammation and high cholesterol.
Taipei, TaiwanAges 20 years+ - NCT07423013Recruiting
Teprotumumab treatment for active thyroid eye disease
This trial tests a new version of an antibody treatment (teprotumumab) for people with active thyroid eye disease. It aims to reduce bulging and inflammation of the eyes, and you must have had symptoms for less than 9 months to join.
BeijingAges 18–80 - NCT07547930RecruitingPhase 2
Tofacitinib for Steroid-Resistant Thyroid Eye Disease
This study tests whether tofacitinib, a new type of immune-modulating medication, can help people with moderate-to-severe thyroid eye disease (Graves' orbitopathy) whose eyes haven't improved with standard steroid treatments. The goal is to reduce eye swelling, bulging, and inflammation that affects daily life.
Xiamen, FujianAges 18–75 - NCT07548632RecruitingPhase 2/Phase 3
Testing a new eye drop medicine for dry eye disease
This study tests whether licaminlimab, a new type of eye drop medicine, helps relieve dry eye disease. You'll use the study medicine for several weeks while doctors track how your symptoms and eye health improve.
Aliso Viejo, CaliforniaAges 18 years+ - NCT07597200RecruitingPhase 1
Cizutamig treatment for active thyroid eye disease
This study tests a new drug called cizutamig for thyroid eye disease (TED), a condition where the eye muscles and tissues swell due to Graves' disease. The drug is designed to reduce inflammation and may help improve symptoms like eye bulging, double vision, and discomfort.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07623382RecruitingEarly Phase 1
Stem Cell Treatment for Dry Eye Disease
This early-stage trial tests whether special cells derived from umbilical cord tissue can help treat dry eye disease. The treatment uses tiny particles called extracellular vesicles that may reduce eye dryness and improve comfort.
Xiamen, ChinaAges 18 years+ - NCT07656688RecruitingPhase 2
Finding the best dose for a dry eye treatment
This trial tests different doses of a new eye drop (HUC1-394) to see which dose works best for people with moderate to severe dry eye disease. You may qualify if your dry eye symptoms have lasted at least 3 months and you have low tear production along with other signs of dry eye.
SeoulAges 19 years+ - NCT07503886RecruitingPhase 2
Study of an eye drop for dry eye disease
This trial tests a new eye drop called DFL24498 to see if it helps people with dry eye disease. You may qualify if your dry eye is moderate to severe and other treatments haven't worked well for you.
Chandler, ArizonaAges 18 years+ - NCT06275373Recruiting
Teprotumumab for thyroid eye disease study
This study tests if the drug teprotumumab can help with symptoms of thyroid eye disease, such as bulging eyes, pain, or double vision. It is for adults who are beneficiaries of the Department of Defense (DOD).
Bethesda, MarylandAges 18 years+ - NCT06298890Recruiting
Dry eye pattern after cataract surgery
This study looks at how dry eye symptoms change after cataract surgery. It is for older adults (50–90) having simple cataract surgery for the first time, without other eye problems or certain health conditions.
KaunasAges 50–90 - NCT07268599Enrolling by invitation
Acoltremon for moderate-to-severe dry eye relief
This study tests a new eye drop called Acoltremon to see if it can relieve symptoms of moderate-to-severe dry eye disease. It may be a good option if you have had dry eye for at least 6 months and use artificial tears.
Encino, CaliforniaAges 18–60 - NCT07753603RecruitingPhase 3
Linsitinib for active moderate to severe thyroid eye disease
This study tests an experimental pill (linsitinib) for people with active thyroid eye disease. Participation may help reduce eye bulging and other symptoms, especially if other treatments haven't worked.
Las Vegas, NevadaAges 18 years+ - NCT07732010RecruitingPhase 4
Tryptophan for dry eye disease
This trial tests whether a dietary supplement called TRYPTYR can improve dry eye symptoms. You may qualify if you have moderate dry eye with certain signs, like short tear breakup time and staining on your eye surface.
New York, New YorkAges 18 years+ - NCT05414994Recruiting
Study eye bacteria in healthy and eye disease
This study compares the tiny living organisms (“ocular microbiome,” meaning eye-surface bacteria) in different eye conditions. It may help researchers understand how these eye bacteria relate to diseases and why some people develop problems with vision.
Nashville, TennesseeAges 18 years+ - NCT06976515Recruiting
Remote study for evaporative dry eye disease
This study tests if people with evaporative dry eye can monitor their condition from home using a smartphone app and mail-in tests. No treatment is given; the goal is to see if remote research is possible.
San Francisco, CaliforniaAges 18 years+ - NCT06775561Recruiting
Study of hidden DNA causes for rare neuromuscular and epilepsy diseases
This study is for people with a neuromuscular disease or epilepsy whose genetic testing hasn't found a clear answer. It uses advanced techniques to look at parts of the DNA that don't code for proteins, to find hidden causes and help guide future treatments.
BolognaAges Any age - NCT07266948RecruitingPhase 4
How TRYPTYR eye drops affect dry eye symptoms and daily life
This study tests a new eye drop called TRYPTYR to see if it can improve quality of life and daily tasks for people with dry eye disease who are unhappy with their current treatment, Restasis. Participants will stop using Restasis and switch to TRYPTYR for about 4 weeks.
Pittsburg, KansasAges 18–75 - NCT06569758RecruitingPhase 1
A study of GenSci098 for active thyroid eye disease
This study tests a new medication called GenSci098 for people with active thyroid eye disease. It aims to reduce eye symptoms like redness, swelling, and bulging, and improve quality of life.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06601101RecruitingPhase 3
Insulin drops for faster healing after corneal crosslinking
This trial tests whether insulin eye drops can help the cornea heal faster after corneal crosslinking, a procedure to treat keratoconus. It is for people with keratoconus who do not have diabetes, severe dry eye, or certain other eye conditions.
Campinas, São PauloAges 14 years+ - NCT06898853Recruiting
Eye drops for dry eye: A 12-week study
This trial tests whether an anti-inflammatory eye drop (ciclosporin A) can help dry eyes by changing immune cells on the eye's surface. It lasts 12 weeks and may be an option for people with moderate to severe dry eye.
Sydney, New South WalesAges 18 years+ - NCT02435940Recruiting
Registry for inherited eye vision conditions
This study is a registry, meaning it collects information about people with inherited retinal (retina) diseases. It may help researchers learn how these conditions progress and connect you with future studies or treatments.
Columbia, MarylandAges Any age
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Common questions
- Are there clinical trials for eye diseases?
- Yes. Clin2 currently lists 181 recruiting eye diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a eye diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a eye diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.