Clin2
NCT06275373Possibly a fitRecruiting

Teprotumumab for thyroid eye disease study

Thyroid Eye DiseaseGraves OphthalmopathyGraves Disease

Part of Eyes & vision, Genetic & congenital, Hormones & metabolism, Immune system & allergy clinical trials.

This study tests if the drug teprotumumab can help with symptoms of thyroid eye disease, such as bulging eyes, pain, or double vision. It is for adults who are beneficiaries of the Department of Defense (DOD).

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
100 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You must be a DOD beneficiary (such as active duty, retiree, or family member).
  • You must be 18 years or older.
  • You must have symptoms of thyroid eye disease like bulging eyes, eye pain, double vision, or eyelid swelling or redness.
  • You must not have severe vision loss from pressure on the optic nerve that needs emergency surgery or radiation.
  • You must not have uncontrolled diabetes or uncontrolled inflammatory bowel disease.
  • You must not be pregnant or trying to become pregnant.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07265258Recruiting· Phase 4
Teprotumumab for active thyroid eye disease

This study tests a drug called teprotumumab for people with active thyroid eye disease. It is designed to help reduce eye bulging and other symptoms, and may be an option if you have not had strong treatments before.

Shanghai, Shanghai Municipality
NCT07423013Recruiting
Teprotumumab treatment for active thyroid eye disease

This trial tests a new version of an antibody treatment (teprotumumab) for people with active thyroid eye disease. It aims to reduce bulging and inflammation of the eyes, and you must have had symptoms for less than 9 months to join.

Beijing
NCT07308964Not yet recruiting· Phase 4
Comparing 4 versus 8 Tepezza treatments for thyroid eye disease

This trial compares two different lengths of treatment with Tepezza (teprotumumab) for thyroid eye disease. It aims to see if 4 treatments are as effective and safe as 8 treatments, which could mean fewer infusions for patients who respond early.

NCT07594912Not yet recruiting· Phase 2
Medication comparison after urgent eye surgery for thyroid eye disease

This trial compares a newer medication (teprotumumab) with standard steroid treatment for people with thyroid eye disease and vision loss who are about to have urgent surgery to relieve pressure on the optic nerve. The goal is to see which approach better protects and restores vision after surgery.

Guangzhou, Guangdong
NCT07832136Not yet recruiting· Phase 4
Veligrotug for thyroid eye disease that returned after teprotumumab

This trial tests a new medicine (veligrotug) for people with thyroid eye disease whose symptoms returned after completing teprotumumab. It aims to see if veligrotug can help again.

Newport Beach, California
NCT07720635Not yet recruiting· Phase 3
New medicine for thyroid eye disease

This trial tests a new medicine (KHN939) for people with moderate-to-severe active thyroid eye disease. If you qualify, the study may help reduce bulging eyes and double vision.

Shanghai, Shanghai Municipality

Hear when a new Graves Ophthalmopathy trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.