Clinical trials
Eye Diseases clinical trials
Below are recruiting eye diseases clinical trials, each written for real people, not researchers. We’re tracking 181 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03587948Recruiting
Diabetes eye study for teens with diabetes
This study looks at how diabetes affects the eyes in children and teens. It may help doctors better detect or understand eye problems earlier in people with diabetes.
Shanghai, Shanghai MunicipalityAges 5–18 - NCT07676084RecruitingPhase 4
Over-the-counter lubricating eye drops for dry eye
This study tests whether over-the-counter lubricating eye drops can improve dry eye symptoms and eye comfort. It compares the drops to no treatment to see how well they work.
Andover, MassachusettsAges 18 years+ - NCT07618364Recruiting
Rinsing to reduce eye inflammation in dry eye disease
This study tests whether rinsing the eye surface helps reduce inflammation and symptoms in people with dry eyes. Participants must have a specific inflammatory marker (MMP-9) in both eyes.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06812845Recruiting
Eye disease patterns at Sohag University Hospital
This study looks at the different types of eye diseases in people who visit the eye testing unit. It helps doctors understand what conditions are most common so they can improve care.
SohagAges Any age - NCT06112340RecruitingPhase 2/Phase 3
Extension study of linsitinib for thyroid eye disease
This trial tests two doses of an oral medication (linsitinib) for people with active, moderate-to-severe thyroid eye disease who were in a previous study and didn't improve enough or had their bulging come back. It aims to see if continuing treatment can help with eye bulging and other symptoms.
Miami, FloridaAges 18 years+ - NCT06841471Recruiting
Role of Corneal Nerves in Dry Eye Disease
This study looks at how the nerves in the front of the eye (corneal nerves) relate to dry eye disease. It compares people with dry eye to those without to understand differences.
OltenAges 18 years+ - NCT06891443RecruitingPhase 3
Study of Sepofarsen for LCA type 10
This study tests an investigational RNA therapy called sepofarsen for people with Leber Congenital Amaurosis (LCA) type 10, a rare inherited eye disease that causes severe vision loss from birth. The goal is to see if it can slow or improve vision loss.
San Francisco, CaliforniaAges 6 years+ - NCT06874283Recruiting
Eye problems from cancer treatment registry
This study collects information and eye health data from people who have had cancer treatment, including stem cell transplants. It helps doctors understand how cancer therapies affect the eyes over time.
Baltimore, MarylandAges 18 years+ - NCT05865457Recruiting
Testing two eye treatments for dry eye symptoms
This trial compares two different dry-eye eye drops to see which works better and is safe. You may be able to join if you’ve had dry eye for at least 3 months and meet specific eye-test results.
GrazAges 18 years+ - NCT05865379Recruiting
Tested eye drops for dry eye relief and safety
This trial studies whether BUFY01 eye drops work better than SVS20 for treating dry eye disease. You may be able to join if you have dry eye symptoms for at least 3 months and meet eye exam score and tear-test requirements.
LeuvenAges 18 years+ - NCT02771236Recruiting
Study of inherited eye conditions in families
This study looks at families who have inherited (passed down) eye conditions, using eye exams and blood tests. It may help researchers understand what causes these conditions and find better ways to diagnose them.
La Jolla, CaliforniaAges 4–120 - NCT02471287Recruiting
Genetics study for inherited eye conditions
This study looks at genes in people with inherited eye conditions and in close family members who may or may not have the condition. It helps researchers understand what causes these eye diseases and how they might be better studied in the future.
Bethesda, MarylandAges 1–120 - NCT06359795Recruiting
PET Scan for Thyroid Eye Disease Activity
This study uses a special PET/CT scan (with a tracer called 18F-AlF-FAPI) to see how active your thyroid eye disease is. It may help doctors better understand and manage the condition.
Beijing, Beijing MunicipalityAges 18–80 - NCT07835607Recruiting
Comparing pet scans and mri for thyroid eye disease
This study compares two PET imaging methods and an MRI to see which better shows inflammation in thyroid eye disease. Participation may help improve detection and monitoring of this condition.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT07656688RecruitingPhase 2
Finding the best dose for a dry eye treatment
This trial tests different doses of a new eye drop (HUC1-394) to see which dose works best for people with moderate to severe dry eye disease. You may qualify if your dry eye symptoms have lasted at least 3 months and you have low tear production along with other signs of dry eye.
SeoulAges 19 years+ - NCT07622368RecruitingPhase 1
Testing IBI3031 for Active Thyroid Eye Disease
This early-stage trial tests a new drug called IBI3031 to treat active thyroid eye disease (TED), a condition where the immune system attacks muscles and tissue around the eyes, causing swelling, bulging, and sometimes double vision. The study aims to see if this drug can reduce inflammation and improve symptoms.
Shenyang, LiaoningAges 18–75 - NCT07623382RecruitingEarly Phase 1
Stem Cell Treatment for Dry Eye Disease
This early-stage trial tests whether special cells derived from umbilical cord tissue can help treat dry eye disease. The treatment uses tiny particles called extracellular vesicles that may reduce eye dryness and improve comfort.
Xiamen, ChinaAges 18 years+ - NCT07597200RecruitingPhase 1
Cizutamig treatment for active thyroid eye disease
This study tests a new drug called cizutamig for thyroid eye disease (TED), a condition where the eye muscles and tissues swell due to Graves' disease. The drug is designed to reduce inflammation and may help improve symptoms like eye bulging, double vision, and discomfort.
Hefei, AnhuiAges 18–75 - NCT07548632RecruitingPhase 2/Phase 3
Testing a new eye drop medicine for dry eye disease
This study tests whether licaminlimab, a new type of eye drop medicine, helps relieve dry eye disease. You'll use the study medicine for several weeks while doctors track how your symptoms and eye health improve.
Aliso Viejo, CaliforniaAges 18 years+ - NCT07547930RecruitingPhase 2
Tofacitinib for Steroid-Resistant Thyroid Eye Disease
This study tests whether tofacitinib, a new type of immune-modulating medication, can help people with moderate-to-severe thyroid eye disease (Graves' orbitopathy) whose eyes haven't improved with standard steroid treatments. The goal is to reduce eye swelling, bulging, and inflammation that affects daily life.
Xiamen, FujianAges 18–75 - NCT07503886RecruitingPhase 2
Study of an eye drop for dry eye disease
This trial tests a new eye drop called DFL24498 to see if it helps people with dry eye disease. You may qualify if your dry eye is moderate to severe and other treatments haven't worked well for you.
Chandler, ArizonaAges 18 years+ - NCT07438405RecruitingPhase 2
Long-term safety study of AMG 732 for thyroid eye disease
This trial tests the long-term safety and effectiveness of AMG 732 for people with moderate-to-severe thyroid eye disease who have already completed an Amgen study of this drug. It allows continued treatment without needing immediate eye surgery.
Little Rock, ArkansasAges 18–99 - NCT07423013Recruiting
Teprotumumab treatment for active thyroid eye disease
This trial tests a new version of an antibody treatment (teprotumumab) for people with active thyroid eye disease. It aims to reduce bulging and inflammation of the eyes, and you must have had symptoms for less than 9 months to join.
BeijingAges 18–80 - NCT07413172RecruitingPhase 2
Testing serum tears for severe dry eye
This study tests whether eye drops made from your own blood serum (with a natural lubricant) can relieve moderate-to-severe dry eye better than a standard salt solution. If you have dry eye from certain immune conditions or nerve damage, this may help find a more effective treatment.
Miami, FloridaAges 18 years+
Hear when a new Eye Diseases trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Eye Diseases trials by city
Studies with a site in or near these metro areas.
Eye Diseases trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for eye diseases?
- Yes. Clin2 currently lists 181 recruiting eye diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a eye diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a eye diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.