Clinical trials
Frailty clinical trials
Below are recruiting frailty clinical trials, each written for real people, not researchers. We’re tracking 265 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07463352Recruiting
Pre-surgery nutrition for frail seniors with hip fractures
This study tests if giving a special protein drink before surgery helps frail older adults with a broken hip recover better. It might reduce complications after surgery.
DüzceAges 65 years+ - NCT07464106Recruiting
Tricuspid valve treatment study for older adults
This study tests if a less invasive tricuspid valve repair or replacement can protect kidney function and improve physical activity in older adults with severe tricuspid valve leakage.
StuttgartAges 18 years+ - NCT07475767Recruiting
Ultrasound and nutrition in surgical ICU patients
This trial uses ultrasound to check muscle and body composition in patients recovering from surgery in the ICU. It also looks at how nutrition affects recovery, so you may be asked about your diet.
OsijekAges 18 years+ - NCT04923087Recruiting
Sound and eating pleasure study for older adults
This trial tests if listening to sounds while eating can make the experience more enjoyable for older adults in hospitals or nursing homes. If you are 65 or older and can safely eat cookies, you may be eligible.
NiceAges 65 years+ - NCT07497334Recruiting
Combined therapy for older adults with mild thinking and mobility issues
This study tests a program that combines mental exercises, physical training, and brain stimulation to help older adults with mild thinking and mobility problems stay independent. It aims to improve walking, memory, and daily function.
Hong KongAges 60–90 - NCT07505758Recruiting
Recovery after surgery in adults 80 and older
This study looks at how well adults aged 80 or older recover after planned surgery that requires an overnight hospital stay. The goal is to understand recovery using a simple questionnaire.
Barcelona, BarcelonaAges 80 years+ - NCT07513701Recruiting
Building Strength and Balance in Older Adults
This study tests whether a home-based exercise program can help older adults who are experiencing physical weakness improve their strength, balance, and overall resilience. You'll do exercises online at home over several months to see if this approach helps you stay independent and active.
Hong Kong, Hong KongAges 60–90 - NCT07525583Recruiting
Screening and Preventing Decline in Older Adults' Physical Ability
This study helps doctors identify older adults at risk of losing physical strength and independence, and tests ways to prevent that decline. You'll be screened for your overall fitness and given guidance to stay healthy as you age.
SingaporeAges 60 years+ - NCT07531836Recruiting
Exercise and wellness program before breast cancer surgery
This trial tests whether a personalized exercise and wellness program before surgery helps older adults with breast cancer recover better and stay stronger. You would work with a team to prepare your body for surgery over several weeks.
Pamplona, NavarreAges 65 years+ - NCT07561138Recruiting
Nutrition and Exercise Training Before Liver Transplant
This study tests whether eating better and doing gentle exercise before your liver transplant can help you stay healthier and recover better after surgery. You'll work with a nutrition expert and exercise specialist to prepare your body for transplant.
Athens, AtticaAges 18–70 - NCT07563777Recruiting
Long-term study of human aging and health
This is a long-term research study that follows people over time to understand how humans age. Researchers will collect information about your health and lifestyle to learn what helps people stay healthier as they get older.
Boulder, ColoradoAges 18 years+ - NCT07597850RecruitingPhase 2
TCM formula versus HMB supplement for muscle strength in older adults
This study compares a traditional Chinese medicine formula with HMB (a muscle-building supplement) to see which helps preserve muscle strength and bone health in adults aged 65 and older who are starting to show signs of frailty. Both treatments aim to help you stay stronger and more active as you age.
TaipeiAges 65 years+ - NCT07627919Recruiting
Strength training and high-protein diet for frail older women
This study tests whether combining resistance exercises with a protein-rich diet can improve muscle strength and overall function in older women with weak muscles. You would attend supervised workouts and follow a specific eating plan for several weeks.
El-Sheikh Zayed CityAges 60–70 - NCT07633483Recruiting
Anxiety and Frailty in Older Adults Having Hip Replacement
This study watches how nervous patients feel before hip replacement surgery and how that connects to their overall strength and ability to bounce back. Researchers want to understand whether anxiety levels and frailty affect each other in older adults.
Istanbul, IstanbulAges 65 years+ - NCT07646782Recruiting
Human Observatory Study: Aging and Longevity Research
This study observes how people age over time to better understand what helps people live longer and healthier lives. You'll share health information through surveys or online screening, and researchers will track changes in your health and wellbeing.
Boulder, ColoradoAges 18 years+ - NCT07652892Recruiting
Fatty Liver, Memory, and Health in Men and Women
This study looks at how fatty liver disease (related to metabolism) affects memory, strength, and quality of life—especially comparing men and women. It helps understand why some people with fatty liver feel more tired or have trouble thinking clearly.
Barcelona, BarcelonaAges 20–80 - NCT07669168Recruiting
Health study comparing usual care vs. extra support
This study looks at whether adding extra health support helps people stay healthier over time. You would be followed for a while and asked to share how you are doing.
Boulder, ColoradoAges 18 years+ - NCT07373119Enrolling by invitation
Frailty reduction in stable heart disease patients
This study tests a program to reduce frailty in older adults with stable coronary artery disease. The goal is to improve strength and well-being in people who are not having recent heart problems.
Barcelona, Select...Ages 70 years+ - NCT07330882Enrolling by invitation
Heart health app study for coronary disease
This study tests a smartphone app to help people with coronary heart disease manage their health. You may be eligible if you have been diagnosed with coronary heart disease, can use a smartphone, and have no serious health issues that would limit exercise.
BengbuAges 18–80 - NCT07310667Enrolling by invitation
Frailty and muscle thickness in older ICU patients
This study looks at how frailty relates to muscle thickness in the thigh for patients over 65 who stay in the intensive care unit for at least a week. It aims to find ways to better support recovery.
Altındağ, AnkaraAges 65 years+ - NCT07245186Enrolling by invitation
Healthy living program for kidney decline
This study tests a program to help people with chronic kidney disease (CKD) stay healthy through diet tracking and other proactive steps. It focuses on people whose kidney function has declined but who are not yet on dialysis.
Shanghai, Shanghai MunicipalityAges 18–90 - NCT07143084Enrolling by invitation
Nutrition and frailty in ICU patients over 65
This study looks at how nutrition relates to frailty in older adults staying in the intensive care unit (ICU). It may help find better ways to support recovery.
Altındağ, AnkaraAges 65 years+ - NCT07127692Enrolling by invitation
Medicines and muscle loss in older adults with falls
This study looks at whether certain medicines might make muscle loss and falls worse in older adults. If you are 65 or older, have been diagnosed with sarcopenia, and have fallen recently, this trial may help find out if your medications could be improved.
Gillingham, KentAges 65 years+ - NCT05307666Enrolling by invitationPhase 4
Older adults using many medications may get simpler care
This study looks at whether older adults do better when their medication plan is simplified. You may be able to join if you’re at least 80, live in the community, and take 6 or more regular oral medications.
Edmonton, AlbertaAges 80 years+
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Common questions
- Are there clinical trials for frailty?
- Yes. Clin2 currently lists 265 recruiting frailty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a frailty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a frailty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.