Clinical trials
Frailty Syndrome clinical trials
Below are recruiting frailty syndrome clinical trials, each written for real people, not researchers. We’re tracking 35 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04518423Recruiting
Study frailty and fitness changes in older adults living at home
This study looks at how “frailty” (lower strength and resilience) and “pre-frailty” change over time in older adults who live at home. It may help researchers understand what factors affect aging and strength, so future care can start earlier.
OpoleAges 65 years+ - NCT06208527RecruitingPhase 2
Nicotinamide Riboside for Frailty in Older Adults
This trial tests whether a daily supplement called nicotinamide riboside can help older adults who feel weak or frail to get stronger and more energetic. It lasts for several months and involves simple tests like a walking test and memory checks.
Bergen, VestlandAges 75 years+ - NCT06870149Recruiting
Dance program to improve mobility in older adults at risk
This study tests whether a structured dance program (called GERAS DANCE) can help older adults who are frail or at risk of losing mobility. You would attend dance sessions at the YMCA twice a week, and researchers will see if it improves your walking and daily function.
Hamilton, OntarioAges 65–100 - NCT07345832Recruiting
Volunteer-led lifestyle program for older adults with muscle loss
This study tests a volunteer-led program to improve muscle health in older adults with sarcopenia. It uses a mobile app to guide exercise and nutrition, and aims to see if this approach helps people regain strength.
Hong KongAges 60 years+ - NCT06104696Recruiting
Comprehensive Geriatric Assessment in Kidney Transplant Patients Over 60
This study looks at how a full health review (geriatric assessment) can help older adults who are getting or have gotten a new kidney. It aims to improve care and outcomes for patients aged 60 and over.
PragueAges 60 years+ - NCT06467149Recruiting
Comparing Frailty Screenings in Older Breast Cancer Patients
This study compares different ways to check frailty (a measure of how well your body handles stress) in women with breast cancer who are 50 or older. The goal is to find which screening tool best predicts health outcomes during treatment.
ChongqingAges 50 years+ - NCT06965972Recruiting
Study of frailty and dependence in older adults
This study follows older adults to understand frailty and dependence over time. It may help improve care for people your age.
Barcelona, CataloniaAges 65–120 - NCT07367828Recruiting
Frailty screening for older adults before surgery
This study tests how well simple frailty screening tools predict recovery and complications after major surgery in people aged 70 and older. The goal is to help doctors and patients better understand surgical risks.
Reykjavik, HofudborgarsvaedidAges 70 years+ - NCT07452263Recruiting
Frailty screening tool for older adults before major surgery
This study tests a simple frailty screening tool in older adults before major surgery. It aims to see if the tool helps identify patients who might need extra support before and after their operation.
Reykjavik, HofudborgarsvaedidAges 70 years+ - NCT03995342Enrolling by invitation
Study gut bacteria and frailty in older adults
This study looks at whether gut bacteria (intestinal flora) are linked to frailty in people age 65 and older. It will also test an intervention to see if changing gut bacteria can help reduce frailty.
Xi'an, ShaanxiAges 65 years+ - NCT05091645Recruiting
Testing a Greek version of a frailty screening for hip fracture patients
This trial checks whether a translated and culturally adapted questionnaire (called the Groningen Frailty Indicator) works well for people age 65+ who have a hip fracture and are having surgery. It may help care teams better understand frailty and plan support after surgery.
LarissaAges 65 years+ - NCT03209414Recruiting
Study of frailty in heart patients receiving heart care
This trial looks at “frailty,” meaning reduced strength and resilience, in older adults with coronary artery disease who are getting heart care. It may help doctors better understand which patients are more at risk and how care decisions could be improved.
Zabrze, Upper SilesiaAges 65 years+ - NCT04524247Recruiting
Testing a custom stent graft for frail aortic aneurysms
This study looks at a specialized, customized stent graft to treat certain aneurysms (bulges) of the aorta in people who may be considered frail. It’s meant to see how well the device works and how safely it can be used in patients who fit specific aneurysm patterns.
Los Angeles, CaliforniaAges 18 years+ - NCT06611228Recruiting
Preventing disability in older hospital patients
This study tests if a program designed for older, frail hospital patients can prevent loss of ability to do daily tasks. It focuses on physical activity, mental engagement, and nutrition to help you stay independent.
Monza, LumbardyAges 70 years+ - NCT04173715Recruiting
Study measuring movement and behavior in older adults
This study checks how well you move and how you behave during simple tasks. It may help researchers understand physical function and activity patterns in older adults.
ToledoAges 65 years+ - NCT04954690Recruiting
Exercise program after kidney transplant for older adults
This trial tests a structured, coached exercise program for people who recently received a living-donor kidney and are coming from dialysis. It may help improve strength and daily function after transplant, especially if starting fitness is difficult.
San Francisco, CaliforniaAges 50 years+ - NCT07465159Recruiting
Prehabilitation for frail patients before hip or knee replacement
This study tests whether a 'prehabilitation' program (tailored exercise and nutrition support before surgery) helps older patients who are frail recover better after hip or knee replacement. Participants will be randomly assigned to either the prehabilitation group or the usual care group.
ReykjavikAges 70 years+ - NCT06069297Recruiting
Prehabilitation before pancreatic cancer surgery
This trial tests whether a pre-surgery program of exercise and nutrition (called prehabilitation) can help people with pancreatic cancer recover better after surgery. Participants will receive guidance on physical activity and diet before their operation.
Milan, LombardyAges 18 years+ - NCT06469437Recruiting
Geriatric check for older adults with type 2 diabetes
This study looks at how a full health check for older adults with type 2 diabetes can help doctors choose the best treatment plan. It aims to improve care for people 60 and older.
Porto Alegre, Rio Grande do SulAges 60 years+ - NCT07338929Recruiting
Physical performance test for kidney transplant evaluation
This study measures physical performance in adults being evaluated for a kidney transplant. It helps understand how fitness levels may affect transplant outcomes.
MartinAges 18 years+ - NCT07348081Recruiting
Digital support program for caregivers of ER patients
This trial tests a digital program that helps caregivers coordinate and monitor care for adults leaving the emergency department. It may reduce stress and make caring easier.
ParisAges 18 years+ - NCT07464106Recruiting
Tricuspid valve treatment study for older adults
This study tests if a less invasive tricuspid valve repair or replacement can protect kidney function and improve physical activity in older adults with severe tricuspid valve leakage.
StuttgartAges 18 years+ - NCT07646782Recruiting
Human Observatory Study: Aging and Longevity Research
This study observes how people age over time to better understand what helps people live longer and healthier lives. You'll share health information through surveys or online screening, and researchers will track changes in your health and wellbeing.
Boulder, ColoradoAges 18 years+ - NCT06444321Recruiting
Integrated care for frail patients with heart failure
This trial tests a special care program for people with both frailty (being weak or vulnerable) and heart failure (when the heart doesn't pump well). The program brings together different types of support to help you manage your health better after a hospital stay.
Drammen, AkershusAges 18 years+
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Common questions
- Are there clinical trials for frailty syndrome?
- Yes. Clin2 currently lists 35 recruiting frailty syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a frailty syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a frailty syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.