Clinical trials
Frailty clinical trials
Below are recruiting frailty clinical trials, each written for real people, not researchers. We’re tracking 265 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07111585Recruiting
Personal health coaching for heart failure patients
This study tests whether personalized health coaching helps people who are frail and have been hospitalized for heart failure. If you are 40 or older, recently in the hospital for heart failure, and feeling weak or vulnerable, this program may support your recovery.
IncheonAges 40 years+ - NCT07136168Recruiting
Healthy aging through movement and community engagement
This trial explores whether staying active and engaged helps healthy older adults stay independent. You'll take part in community-based activities designed to support movement and social connection.
Borgholm, County of KalmarAges 67–84 - NCT07144527Recruiting
NMN supplement for exercise in healthy older adults
This trial tests whether a supplement called nicotinamide mononucleotide (NMN) can help healthy adults aged 60 to 80 improve their exercise tolerance. You'll take the supplement and do supervised cycling sessions to see if it boosts your stamina.
Beverly Hills, CaliforniaAges 60–80 - NCT07151365Recruiting
Plant-based diets and healthy aging study
This study looks at how a plant-based diet might help people age in a healthy way. It is for adults 40 and older who are part of the Tzu Chi Foundation and are joining a health checkup program.
Dalin, ChiayiAges 40 years+ - NCT07205133Recruiting
Vibration therapy for older adults to improve muscle health
This trial tests whether whole body vibration therapy can help improve muscle health in older adults. You stand on a vibrating platform for a few minutes a few times a week, which may strengthen your muscles and reduce frailty.
SingaporeAges 65 years+ - NCT07207044Recruiting
Fasting and exercise to slow aging
This trial tests whether a specific schedule of fasting (time-restricted eating) combined with exercise can help slow aging. You will follow a daily eating window and perform prescribed physical activity to see how it affects your health.
Copenhagen, Copenhagen NAges 20 years+ - NCT07234565Recruiting
Improving social frailty through interactive learning
This trial tests a social program delivered over WeChat to help older adults with heart failure who feel socially frail. It aims to improve social connections and reduce frailty through interactive learning.
ShanghaiAges 60 years+ - NCT07237334Recruiting
Emergency care study for older adults (GEM-U)
This study tracks health outcomes for older adults who are cared for in a special emergency unit designed for their needs. It helps researchers learn what works best for seniors who come to the emergency room with medical problems.
Limerick, MunsterAges 75 years+ - NCT07175376Recruiting
Building resilience for older adults starting cancer treatment
This study tests a program designed to help older adults with cancer who are starting a new chemotherapy or immune therapy. The program uses an electronic frailty score to provide extra support and resources to improve your overall well-being during treatment.
Charlotte, North CarolinaAges 65 years+ - NCT07415382Recruiting
Frailty, multitasking, and daily activities in older adults
This study looks at how frailty affects the ability to do two things at once (like walking while talking) and how that relates to everyday tasks in people 65 and older.
Konya, KaratayAges 65–85 - NCT07259499Recruiting
Predictors of emergency visits in frail older adults
This study looks at why frail older adults go to the emergency room. Researchers want to see if blood tests and brain scans can help predict who needs emergency care. Participation involves one interview and having had a recent brain scan and blood work.
Pisa, PisaAges 65 years+ - NCT07308314Recruiting
Taining County chronic disease management study
This study looks at how to manage chronic diseases (like diabetes or high blood pressure) better for people living in Taining County. It involves completing a survey and regular check-ins over the next few years.
Fuzhou, FujianAges 18 years+ - NCT07338929Recruiting
Physical performance test for kidney transplant evaluation
This study measures physical performance in adults being evaluated for a kidney transplant. It helps understand how fitness levels may affect transplant outcomes.
MartinAges 18 years+ - NCT07348081Recruiting
Digital support program for caregivers of ER patients
This trial tests a digital program that helps caregivers coordinate and monitor care for adults leaving the emergency department. It may reduce stress and make caring easier.
ParisAges 18 years+ - NCT07351526Recruiting
Rehabilitation study for patients after hospital stay
This study looks at how patients do during inpatient rehab after a hospital stay. It aims to understand what helps people recover and what their recovery looks like.
Limerick, MunsterAges 18 years+ - NCT07366684Recruiting
Heart attack study for adults 75 and older
This study looks at how frailty and other health factors affect recovery in people 75 and older who have had a heart attack or unstable chest pain. It may help doctors better understand who is at higher risk and how to improve care for older adults.
NišAges 75 years+ - NCT07392944Recruiting
Exercise program for older adults in nursing homes
This trial tests a multicomponent exercise program for older adults living in nursing homes. The goal is to see if it improves physical function, thinking skills, and reduces falls risk.
PortoAges 65 years+ - NCT02856620Recruiting
Study heart function and frailty in people with aortic valve narrowing
This study looks at how heart mechanics, blood markers, and frailty relate to symptoms and heart measurements in people with aortic stenosis (a stiff, narrowed heart valve). It may help doctors better understand who is at higher risk and how disease changes over time.
Montreal, QuebecAges 18 years+ - NCT07677072Recruiting
Studying a blood protein to detect hidden bone fragility
This study looks at a protein called lumican in the blood to see if it can help find women who have fragile bones even if their bone density test looks normal. It's for postmenopausal women who are already getting a bone density scan as part of their routine care.
Küçükçekmece, IstanbulAges 45 years+ - NCT07414095Recruiting
Frailty assessment before liver transplant and outcomes
This study looks at how frail liver transplant candidates are before surgery and whether that affects their recovery afterward. Participants will complete simple physical and mental tasks to help doctors better understand their overall health before the transplant.
IzmirAges 18–65 - NCT07441343Recruiting
Polyphenol supplements and exercise for older adults
This study tests whether taking polyphenol supplements (natural compounds found in plants) combined with exercise can improve physical performance in older adults. If you are over 60 and generally healthy, you may be able to join.
Kingston, OntarioAges 60 years+ - NCT07441382Recruiting
Comparing treatments for frail older adults with atrial fibrillation
This study tests whether combining a heart procedure (catheter ablation) with a device to close the left atrial appendage (LAAO) is safer or better than blood thinners alone for frail patients 75 years or older with atrial fibrillation and high stroke risk. It aims to find a treatment that reduces stroke while lowering bleeding risks.
Guangzhou, GuangdongAges 75 years+ - NCT07447453Recruiting
Motivational support for exercise in healthy aging
This trial tests if motivational support can help adults 70+ stay active with a home exercise program. It may help you maintain strength and mobility as you age.
Getafe, MadridAges 70 years+ - NCT07454616Recruiting
Supplement and exercise study for pre-frail adults
This study tests whether a special nutrient supplement combined with a simple exercise routine can improve health markers linked to living longer. It is designed for adults who are starting to feel less strong or energetic but are not yet frail.
SingaporeAges 50–80
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Common questions
- Are there clinical trials for frailty?
- Yes. Clin2 currently lists 265 recruiting frailty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a frailty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a frailty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.