Clinical trials
Frailty clinical trials
Below are recruiting frailty clinical trials, each written for real people, not researchers. We’re tracking 245 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06343727Recruiting
Egg White Pudding for Low Protein in Kidney Dialysis
This trial tests whether eating a special high-protein egg white pudding every day for 12 weeks can help people on dialysis with low protein levels. It's for adults with chronic kidney disease who are on center-based hemodialysis and have a low blood protein level called albumin.
Winnipeg, ManitobaAges 18 years+ - NCT06309225Recruiting
Adjusted Chemoradiation for HPV Throat Cancer in Older Adults
This trial tests adjusting the dose of chemotherapy and radiation for older adults (65+) with HPV-related throat cancer. The goal is to find a treatment that is effective but gentler on the body.
Jacksonville, FloridaAges 65–99 - NCT06286891Recruiting
Frailty and lung function after pulmonary endarterectomy
This study looks at how frailty, physical ability, and lung function change in people who have had surgery to remove blood clots from the lungs (pulmonary endarterectomy). It aims to help doctors better understand recovery after this procedure.
São Paulo, São PauloAges 18 years+ - NCT06244199Recruiting
Transition to cardiac rehabilitation for veterans with heart disease
This study tests a program that helps Veterans with heart disease start cardiac rehabilitation (a supervised exercise and education program to improve heart health) while they are still in the hospital. It aims to overcome barriers like other health problems and frailty, and may add up to 2 days to your hospital stay.
Boston, MassachusettsAges 18 years+ - NCT06247189Recruiting
ICOPE program for older adults with myeloma
This trial tests whether a program called ICOPE MONITOR, which uses a smartphone app or chatbot, can help older adults with multiple myeloma stay healthier and manage their care. It may be a good fit if you are 70+ and starting your first or second treatment.
ToulouseAges 70 years+ - NCT06141798Recruiting
Dialysis Frequency for Older Adults
This trial compares two versus three times weekly dialysis for people aged 60 or older who are just starting maintenance hemodialysis. It aims to find the best schedule for older adults with end stage kidney disease.
Bucheon-siAges 60 years+ - NCT06113016RecruitingPhase 2
Preventing frailty with fisetin and exercise in breast cancer survivors
This study tests whether adding a supplement called fisetin to an exercise program can help prevent frailty in women who have finished chemotherapy for early-stage breast cancer. If you are postmenopausal, have completed chemo within the last year, and can walk a certain distance, you may qualify.
Alhambra, CaliforniaAges Any age - NCT06089083Recruiting
Helping gynecologic cancer patients with frailty recover function
This study tests a program to help gynecologic cancer patients who are frail improve their physical function and quality of life during treatment. It aims to see if extra support can help you stay stronger and recover better.
San Francisco, CaliforniaAges 18 years+ - NCT06089473Recruiting
Home Exercise Program for Frail Kidney Transplant Candidates
This study tests whether a 12-week home exercise program (supervised by video calls) can help people who are frail feel stronger and healthier before a kidney transplant. You'll do exercises at home and connect with a trainer online.
Montreal, QuebecAges 18 years+ - NCT06073106Recruiting
Frailty prevention study for older Asian adults
This trial tests a program to prevent frailty in people aged 50 and older of Asian descent who have recently been diagnosed with a stroke, traumatic brain injury, knee osteoarthritis, or breast cancer. The goal is to help you stay strong and healthy as you recover.
Singapore, SingaporeAges 50 years+ - NCT06040125Recruiting
Exercise for frailty and muscle loss in men with prostate cancer
This trial tests a supervised exercise program to see if it can reduce frailty and muscle loss in men with metastatic prostate cancer who are on hormone therapy. It may help you become stronger and feel better during treatment.
Boston, MassachusettsAges 18 years+ - NCT06039176Recruiting
Learning from the HeartMate 3 device
This study looks at information from the HeartMate 3 LVAD device to learn more about how it works and what it can tell us about the future. It may help people with advanced heart failure who need this specific device.
San Francisco, CaliforniaAges 18–100 - NCT06011499Recruiting
Online lifestyle program for prostate cancer survivors
This study tests an internet-based program to help prostate cancer survivors who are overweight and frail improve their health. You will be assigned to either a lifestyle coaching group or a usual care group, and both groups are followed for about 6 months.
Portland, OregonAges 18 years+ - NCT06027554RecruitingPhase 2
MitoQ for frailty, walking, memory, and blood flow in older adults
This trial tests whether a supplement called MitoQ can improve blood vessel health, walking speed, and thinking skills in older adults who are frail or have mild memory problems. It aims to see if MitoQ helps maintain independence and quality of life.
Farmington, ConnecticutAges 65–80 - NCT05877846Recruiting
Personalized care to improve physical function in older adults
This study looks at precision (personalized) approaches to help older adults improve physical function. It may include giving a specific supplement depending on lab results, and it requires regular study visits and ability to complete procedures.
Chapel Hill, North CarolinaAges 65–85 - NCT05725928Recruiting
Walking-support program for older hospitalized patients
This study tests whether extra help and guidance to walk while you’re in the hospital can improve health and recovery. It’s for older adults who can safely do some walking after being admitted for a medical problem.
Springfield, MassachusettsAges 65 years+ - NCT05720507Recruiting
Testing a coffee-movement program to prevent frailty
This trial studies a program called “Cafe Move” to help people stay physically strong and avoid future frailty. It’s aimed at people who currently live independently and can move on their own.
Missoula, MontanaAges 50–85 - NCT05598112RecruitingEarly Phase 1
Oral stool-based microbiome treatment for healthy aging
This early-stage study tests whether changing the gut bacteria using an oral stool-based treatment (called oral FMT) can improve health in older adults. It aims to see if this approach affects aging-related changes, including gut and body function.
Beijing, Beijing MunicipalityAges 70–85 - NCT05364879Recruiting
Exercise before ovarian cancer surgery
This trial tests whether supervised exercise (before surgery) can help people with advanced ovarian cancer get ready for treatment. It’s meant to improve readiness and safety during the time leading up to surgery.
Halifax, Nova ScotiaAges 18 years+ - NCT05400707Recruiting
Tracking symptoms and other clues in emergency room visits
This study follows people who come to the emergency department to see what symptoms and other factors can help predict what happens next. It may help improve how emergencies are quickly triaged and managed.
BaselAges 18 years+ - NCT05307666Enrolling by invitationPhase 4
Older adults using many medications may get simpler care
This study looks at whether older adults do better when their medication plan is simplified. You may be able to join if you’re at least 80, live in the community, and take 6 or more regular oral medications.
Edmonton, AlbertaAges 80 years+ - NCT05107947Recruiting
Dynamic room lighting to improve sleep and daily body rhythm
This study tests whether changing the light in a hospital room can improve sleep and help your body clock work better in older adults. It may be most helpful if sleep problems or irregular daily rhythms are affecting you in the hospital.
MalmöAges 65 years+ - NCT05131321Recruiting
Testing a frailty-focused plan for serious ankle fractures
This trial studies how best to manage serious ankle or tibia-pilon fractures in older adults who may be frail or have other major health problems. The goal is to improve care decisions and outcomes after injury, especially in people more likely to have complications.
London, OntarioAges 40 years+ - NCT04923087Recruiting
Sound and eating pleasure study for older adults
This trial tests if listening to sounds while eating can make the experience more enjoyable for older adults in hospitals or nursing homes. If you are 65 or older and can safely eat cookies, you may be eligible.
NiceAges 65 years+
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Common questions
- Are there clinical trials for frailty?
- Yes. Clin2 currently lists 245 recruiting frailty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a frailty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a frailty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.