Clinical trials
Gender Dysphoria, Adult clinical trials
Below are recruiting gender dysphoria, adult clinical trials, each written for real people, not researchers. We’re tracking 11 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06351501RecruitingPhase 3
Hormone treatment for gender dysphoria in teenagers
This study tests whether hormone therapy (such as testosterone or estrogen) helps reduce distress in teenagers who feel their gender does not match their body. It aims to see if starting hormones at this age improves mental well-being and overall quality of life.
ParisAges 13–14 - NCT06953908Recruiting
The Copenhagen Gender Identity Study
This trial follows all patients referred to the Center for Gender Identity in Copenhagen to learn more about their experiences and needs. If you are referred there and can read Danish, you may join.
CopenhagenAges 18 years+ - NCT06565663Enrolling by invitation
Decision aid for gender-affirming surgeries
This study tests an online decision tool for people considering metoidioplasty or phalloplasty. The tool helps patients compare surgical options to make informed choices.
Hanover, New HampshireAges 18 years+ - NCT04935164Recruiting
Study of gender dysphoria versus a control group
This study compares people with gender dysphoria to people without it. It looks at differences in symptoms or outcomes and may help researchers better understand how gender dysphoria affects mental well-being.
PoitiersAges 18–60 - NCT06670053Recruiting
Testosterone and brain development in teens
This study looks at how starting testosterone therapy affects brain development in transgender and gender-diverse youth. It may help you and your doctor understand the changes to expect.
Aurora, ColoradoAges 12–20 - NCT07286123Recruiting
Vaginoplasty using fish skin graft for transgender women
This trial tests a new surgical technique for gender-affirming vaginoplasty that uses a fish skin graft (Kerecis) to create the vaginal lining. It may be an option for transgender women planning this type of surgery for the first time.
Cleveland, OhioAges 19–99 - NCT07480590Recruiting
Gender-Affirming Care and Mental Health Study
This study follows adults who are referred to a gender dysphoria assessment clinic in southern Sweden to see how gender-affirming care affects quality of life, work life, and overall health over time.
Malmö, MalmöAges 18 years+ - NCT07624747Recruiting
Brain Health Study for Transgender Adults Starting Hormone Therapy
This study looks at how gender-affirming hormone therapy affects brain health and function in transgender adults. Researchers want to understand the effects of these hormones on the brain before and after treatment begins.
Madison, WisconsinAges 18–45 - NCT07252687Recruiting
How Gender-Affirming Care Affects Breast Perception in Trans Men
This study looks at how gender-affirming treatments (like hormone therapy or chest surgery) affect how trans men feel about their chest. It aims to help understand the best timing for these treatments.
InnsbruckAges 16 years+ - NCT05097820Recruiting
Study of silicone gel testicular implants after placement
This is an observational study that follows people who receive silicone gel-filled testicular implants. It aims to collect real-world information about safety and healing to help improve future care.
Ghent, East-FlandersAges birth–110 years - NCT06428669RecruitingPhase 4
Nitropaste for chest masculinizing surgery
This study tests if applying nitropaste to the chest before surgery improves blood flow to the nipple grafts, which may help them heal better. It is for people having chest masculinizing surgery with a specific technique called double incision and free nipple grafting.
Charlottesville, VirginiaAges 18 years+
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Common questions
- Are there clinical trials for gender dysphoria, adult?
- Yes. Clin2 currently lists 11 recruiting gender dysphoria, adult studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gender dysphoria, adult trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gender dysphoria, adult trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.