Hormone treatment for gender dysphoria in teenagers
Part of Mental health clinical trials.
This study tests whether hormone therapy (such as testosterone or estrogen) helps reduce distress in teenagers who feel their gender does not match their body. It aims to see if starting hormones at this age improves mental well-being and overall quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 13 and 14 years old (age 13.5 years, give or take 6 months).
- You have already started puberty (confirmed by a doctor, like breast or genital development).
- You have been diagnosed with gender dysphoria by two separate psychiatric interviews at least six months apart.
- Your treatment plan was approved by a team of specialists after a visit with a pediatric endocrinologist.
- You do not have any serious medical or mental health conditions that would make hormone therapy unsafe.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how people respond early after starting gender-confirming hormones. It may help doctors understand what changes happen soon after treatment starts and how to manage it safely.
This study looks at how cross-sex hormone treatment affects the heart and fat in the liver. It aims to help understand the safety of hormone therapy in transgender individuals.
This study looks at how puberty blockers and then estradiol (estrogen) may affect heart and metabolism health in teens. It may help doctors understand risks and benefits for transgender youth starting gender-affirming hormone care.
This study looks at how gender-affirming hormone therapy affects brain health and function in transgender adults. Researchers want to understand the effects of these hormones on the brain before and after treatment begins.
This study looks at how starting testosterone therapy affects brain development in transgender and gender-diverse youth. It may help you and your doctor understand the changes to expect.
This trial is a survey asking girls aged 11 to 17 how they feel about starting hormone replacement therapy for hypogonadism. The goal is to understand their experiences and views.
Hear when a new Gender Dysphoria trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.