Clinical trials
General Population (no Specific Condition or Disease) clinical trials
Below are recruiting general population (no specific condition or disease) clinical trials, each written for real people, not researchers. We’re tracking 10,808 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04739072Recruiting
Check colorectal cancer blood tests after curative treatment
This study measures “minimal residual disease,” meaning tiny amounts of cancer that may remain after surgery, using blood samples. It may help doctors better detect who is at higher risk of cancer coming back and guide follow-up care.
Gilbert, ArizonaAges 18 years+ - NCT04742634RecruitingPhase 1/Phase 2
Preemptive drug DEC-C after transplant to reduce hidden cancer
This trial tests whether giving DEC-C (a decitabine-based treatment) soon after an allogeneic transplant can improve outcomes for MDS patients who still have “measurable residual disease” (hidden leftover disease) detectable by a genetic test. It also compares this approach to standard observation if the hidden disease is not detected or if the higher-risk safety checks are not met.
St Louis, MissouriAges 18–75 - NCT04741230Recruiting
Test implant for severe corneal thinning to avoid transplant
This study tests a procedure called Xenia corneal lenticule in people with severe keratoconus or severe post-LASIK corneal thinning who want to avoid a corneal transplant. It aims to improve vision while checking safety and how well the new procedure works over time.
Wolverhampton, West MidlandsAges 18–79 - NCT04745221Recruiting
Fecal microbes therapy to help prevent graft-versus-host disease
This trial studies a treatment made from donor gut microbes to help prevent a common complication after a transplant called acute graft-versus-host disease (aGVHD). It may help by improving the balance and variety of gut bacteria during recovery after haploidentical transplant.
Suzhou, JiangsuAges 18–60 - NCT04743180Recruiting
Registry of a drug balloon for leg artery blockages
This study follows people with blocked blood vessels in the thigh and behind the knee to see how well a drug-coated balloon (“Luminor”) works over 5 years. It’s designed to collect real-world results and track safety and outcomes long term.
Bordeaux, New AquitaineAges 18 years+ - NCT04746534Recruiting
Study for blood-flow problems in the intestines
This study follows adults with intestinal blood-flow problems (from artery or vein issues) to better understand these conditions. It may help doctors plan future diagnosis and treatments for people with sudden or long-lasting intestinal ischemia.
ClichyAges 18 years+ - NCT04746820Recruiting
Brain monitoring in unconscious ICU patients after cardiac arrest
This trial tests a bedside brain-monitoring method (near-infrared light and EEG) in people who are unconscious after severe brain injury from cardiac arrest. The goal is to see whether it can help measure brain function during the first week after admission.
Zurich, Canton of ZurichAges 18 years+ - NCT04748237Recruiting
CT heart scan for intermediate-risk chest pain
This study tests whether a special heart CT scan can help evaluate the cause of chest pain in people at intermediate risk for blocked heart arteries. It may help doctors decide what to do next after an emergency room visit.
StockholmAges 18 years+ - NCT04750070RecruitingPhase 3
Treating shock in young children with severe malnutrition and diarrhea
This study tests a treatment approach to help children who are in “shock” (their body is struggling to maintain blood flow and oxygen) caused by diarrhea and severe undernutrition. It may help care teams stabilize children faster and improve outcomes.
DhakaAges 1 month–4.9 years - NCT04754217Recruiting
Follow-up study after valve graft replacement
This study looks at outcomes after certain heart valve surgeries using a valved graft. It may help doctors understand how well these grafts work over time in people who have had valve replacement surgery.
Birmingham, AlabamaAges 18 years+ - NCT04755153Recruiting
Community health program to lower heart disease risk
This trial tests a community-based health intervention in Chicago to help reduce the risk of cardiovascular (heart and blood vessel) disease. It may help people by offering structured support through local clinics or churches.
Chicago, IllinoisAges 18–89 - NCT04759274Recruiting
Personalized water pill dosing support for kidney and fluid overload
This trial tests a decision-support tool to help your care team safely adjust water pills (“diuretics”) when you have kidney disease and fluid buildup. It may help reduce swelling by guiding dosing using your home weight and blood pressure.
Dallas, TexasAges 18 years+ - NCT04758975RecruitingPhase 2
Venetoclax plus rituximab plus ibrutinib for early CLL
This Phase 2 trial tests a combination of three medicines to treat chronic lymphocytic leukemia (CLL) that has not been treated before and where the goal is to achieve very low remaining disease. It may help some people stay in remission longer, but eligibility depends on your age, organ function, and prior treatments.
Milan, MIAges 18–65 - NCT04761120Recruiting
Follow-up study for specific heart valve repair ring implants
This study follows people who are going to get certain types of heart valve repair rings or bands. It aims to track safety and outcomes after the Abbott device is implanted in routine care over follow-up visits.
Durham, North CarolinaAges 18 years+ - NCT04762134Recruiting
Doxycycline to prevent future bacterial STIs in high-risk men
This trial tests whether taking doxycycline can lower the chance of getting bacterial sexually transmitted infections like syphilis, gonorrhea, and chlamydia. It is aimed at men who have had these infections recently and expect to keep having multiple male partners.
Calgary, AlbertaAges 18 years+ - NCT04763538Recruiting
Hospital patients who agree to share health information
This study tracks how urology patients are doing and measures outcomes using information from your medical history. It may help doctors improve care, as long as you agree to participate.
BielAges 18 years+ - NCT04765865Recruiting
Sodium reduction program testing in Nigeria households
This trial helps test how well Nigeria’s national plan to reduce salt (sodium) works, and how to roll it out more widely. You may be asked to provide samples over a full day to measure salt intake.
Abeokuta, Ogun StateAges 18–69 - NCT04767074Recruiting
Non-drug therapy to reduce long-term cough in lung scarring
This study tests a non-medication cough-control program for people who have lung scarring (interstitial lung disease) and a cough lasting more than 8 weeks. It may help you control coughing better without adding new medicines.
Hamilton, OntarioAges 18–85 - NCT04772170Recruiting
Study wearable and symptom monitoring during respiratory virus challenges
This observational study looks for digital health patterns during studies where people are intentionally exposed to a respiratory virus. If you join a respiratory virus challenge at NIH, you may help researchers discover better ways to monitor and understand illness using wearable devices and shared health data.
Bethesda, MarylandAges 18–65 - NCT04776330RecruitingPhase 1/Phase 2
BCMA-targeted CAR-T for relapsed or refractory multiple myeloma
This trial tests a lab-made immune cell therapy (CAR-T) designed to attack a protein called BCMA on myeloma cells. It’s for adults whose multiple myeloma or related plasma cell disease has come back or didn’t respond to prior treatment, aiming to improve cancer control.
Kunming, YunnanAges 18–75 - NCT04778046RecruitingPhase 2
Study lung pressure treatment for people waiting for transplant
This Phase 2 trial is for adults with pulmonary hypertension who are on the lung transplant waiting list at Duke. It aims to test whether the study treatment can improve lung pressure and related health outcomes, while using things like MRI to monitor changes.
Durham, North CarolinaAges 18 years+ - NCT04779008Recruiting
Remote arm treatment to help blood flow after heart bypass
This trial studies whether a simple, at-home type of treatment using brief arm blood-flow changes can improve blood flow to the heart and outcomes after CABG (heart bypass surgery). It may help some people recover better by protecting the heart around the time of surgery.
Zhengzhou, HenanAges 18–80 - NCT04781322RecruitingPhase 1
Study drug to reduce LDL cholesterol effects in heavy drinkers
This Phase 1 study tests how safe a cholesterol-lowering antibody (alirocumab) is in people who drink heavily but are not seeking alcohol treatment. It also looks at early drug effects in the body to see how it might change cholesterol-related signals.
Bethesda, MarylandAges 21–65 - NCT04784052RecruitingPhase 1/Phase 2
Briquilimab with reduced donor stem cell transplant for Fanconi anemia
This study tests whether a reduced-intensity donor stem cell transplant (with briquilimab as part of the conditioning) can safely treat bone marrow failure in people with Fanconi anemia. It may help by lowering how much intensive treatment is needed before the transplant, while still helping the donor cells grow.
Stanford, CaliforniaAges 2 years+
Hear when a new General Population (no Specific Condition or Disease) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for general population (no specific condition or disease)?
- Yes. Clin2 currently lists 10,808 recruiting general population (no specific condition or disease) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a general population (no specific condition or disease) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a general population (no specific condition or disease) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.