Clinical trials
Gingivitis and Periodontal Diseases clinical trials
Below are recruiting gingivitis and periodontal diseases clinical trials, each written for real people, not researchers. We’re tracking 58 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07262606Recruiting
Saliva protein levels in gum disease severity and smoking
This study looks at a protein called Mitofusin-1 in your saliva to see if its levels are linked to how serious gum disease is, whether you smoke, and how you respond to treatment. Samples will be taken once before any treatment begins.
Erzincan, ErzincanAges 18–65 - NCT07311512Recruiting
Gum treatment and mouthwash study for gum disease
This trial tests if a professional gum cleaning combined with a special mouthwash can improve gum health and blood vessel function. It may help people with early gum disease who haven't had recent gum treatment.
Portsmouth, HampshireAges 30–75 - NCT07312552Recruiting
Gum health, smoking, and saliva markers study
This study looks at how gum health and smoking affect certain proteins in your saliva. It may help researchers understand more about gum disease and inflammation.
IstanbulAges 18–65 - NCT06958874Recruiting
Erythritol for gum pocket healing
This study tests if adding erythritol to standard gum treatment helps close deep gum pockets in people with advanced gum disease (periodontitis).
L’AquilaAges 35 years+ - NCT07421960Recruiting
Periodontitis and sleep quality study
This study looks at how gum disease (periodontitis) might be related to sleep quality. It compares people with healthy gums to those with gum disease.
Istanbul, IstanbulAges 18–65 - NCT07718061Recruiting
Bacteria in dental plaque with orthodontic retainers
This trial studies the types of bacteria found in dental plaque from people who have orthodontic retainers after braces. It aims to understand how retainers affect oral bacteria.
MurciaAges 18–40 - NCT05232331Recruiting
Eat nitrate-rich vegetables to study gum inflammation and mouth bacteria
This study looks at whether eating more nitrate-rich vegetables changes inflammatory markers and the balance of bacteria in the mouth for people with periodontitis (serious gum disease). It may help us understand better diet-based support alongside standard non-surgical gum treatment.
Guadalajara, JaliscoAges 30–65 - NCT06784817Recruiting
Gum health in smokers and heated tobacco users
This study compares gum health in three groups: daily cigarette smokers, exclusive users of heated tobacco products (like IQOS), and never-smokers. It aims to see if heated tobacco has different effects on gums compared to traditional smoking.
Budapest, Pest CountyAges 18 years+ - NCT07306026Recruiting
Testing a toothbrush's bristles on plaque and gums
This trial compares how well different toothbrush bristles remove plaque and affect gum health. It may help find the best toothbrush design for everyday oral care.
Buffalo, New YorkAges 18–70 - NCT07205172Recruiting
Gum looks and teeth crowding in children
This study looks at how the appearance of the gums relates to crowding of teeth in children. It will examine kids in different stages of tooth development to see if there is a link.
RomaAges 5–16 - NCT06745141Recruiting
Gum disease treatment after a heart attack
This trial tests whether treating severe gum disease can improve recovery after a heart attack (STEMI). If you recently had a heart attack and also have serious gum problems, you may be able to join and receive periodontal care.
Shanghai, Shanghai MunicipalityAges 30 years+ - NCT07258303Recruiting
Probiotic Spray for Gum Disease in Older Adults
This trial tests an oral spray that contains good bacteria (probiotics) to help prevent and treat gum disease in older adults. It may be a simple addition to your daily routine to support gum health.
Hanoi, HanoiAges 35 years+ - NCT06882564RecruitingPhase 3
Resveratrol mouthwash for bad breath study
This trial tests whether a special mouthwash with resveratrol (a natural plant compound) can help reduce bad breath caused by gum-related bacteria. It might be a good option if you have bad breath from gingivitis (mild gum inflammation) and are a non-smoking dental student.
Baghdad, Bab Al-MoadhamAges 20–24 - NCT07424846RecruitingPhase 2/Phase 3
Xylitol gum to prevent gum disease and early birth
This trial tests if chewing xylitol gum during pregnancy can reduce gum disease and preterm birth. You would chew gum after meals and attend dental visits and follow-ups.
LilongweAges Any age - NCT07185191Recruiting
Device to treat gum shrinkage and black triangles between teeth
This trial tests a medical device (RDM36) to see if it safely and effectively treats gum shrinkage and black triangles between the front teeth, which can affect your smile.
Brescia, ItalyAges 18 years+ - NCT07739732Recruiting
Gum disease mouth fluid study
This study compares the chemicals in the fluid around teeth between people with gum disease and healthy people. The goal is to find changes that could help understand or detect gum disease.
Catania, ItalyAges 18–70 - NCT07549347Recruiting
Smart Toothbrush vs. Professional Cleaning for Gum Disease
This study tests whether using an intelligent (electric) toothbrush with a smartphone app can manage early gum inflammation as effectively as professional dental cleaning. If you have mild gum disease, this trial may help you avoid or delay professional treatments.
Shanghai, Shanghai MunicipalityAges 18–64 - NCT07666126Recruiting
Uric acid and gum bone health study
This study looks at whether high uric acid levels affect the bone around your teeth. If you are between 18 and 65, have at least 20 natural teeth, and are either healthy or have high uric acid and gum disease, this trial may be for you.
RizeAges 18–65 - NCT06290414Recruiting
Infrared imaging to check gum health
This trial uses a special camera that measures heat in your gums to see if it can tell if your gums are healthy, have gingivitis, or have periodontitis. It may help dentists spot gum disease earlier.
CairoAges 18–60 - NCT07167771Recruiting
Saliva markers for gum disease: a follow-up study
This study follows up with people who already took part in a previous saliva and gum health study. Researchers want to see if certain substances in saliva can predict gum disease progression over time.
MadridAges 18 years+ - NCT06875440Enrolling by invitation
Green tea vs. chlorhexidine mouthwash for gum disease
This trial tests if green tea mouthwash works as well as a standard mouthwash (chlorhexidine) for treating gum inflammation. It also checks how the mouthwash affects certain cells and chemicals in your spit that are linked to gum health.
Tehran, Tehran, Iran.Ages 18–40 - NCT07436325Enrolling by invitation
Comparing gum health for two types of baby tooth crowns
This trial compares how gum health holds up with zirconia vs. stainless steel crowns on baby molars in children aged 3–7. It helps find which crown type may be better for keeping gums healthy.
Buraidah, Al-Qassim ProvinceAges 3–7 - NCT07169305Recruiting
Study on filling placement depth and tooth health
This trial tests how the depth of a filling below the gumline affects the health of the tooth's nerve and surrounding gum tissue. It may help people with cavities that go below the gum to get better care.
Rohtak, HaryanaAges 18 years+ - NCT06900881RecruitingPhase 2/Phase 3
Kefir Mouthwash for Healthy Gums
This clinical trial tests if a mouthwash made from kefir, a fermented milk drink, can reduce gum swelling and bleeding (gingivitis) in young adults. You might benefit if you have mild gum disease but are otherwise healthy.
BaghdadAges 18–28
Hear when a new Gingivitis and Periodontal Diseases trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for gingivitis and periodontal diseases?
- Yes. Clin2 currently lists 58 recruiting gingivitis and periodontal diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gingivitis and periodontal diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gingivitis and periodontal diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.