Clinical trials · California
Health clinical trials in California
We’re tracking 341 recruiting health studies with a site in California — including Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT05799378RecruitingPhase 3
Testing whether stopping hydroxychloroquine is safe in older lupus patients
This trial looks at whether older adults with lupus who have been very stable can safely stop hydroxychloroquine. It may help reduce medication burden, but participants must meet strict stability and eye-safety requirements.
Los Angeles, CaliforniaAges 55 years+ - NCT07223736Recruiting
AI education for new mothers after birth
This study tests an AI-based education tool for first-time mothers to help with recovery and reduce loneliness after childbirth. You participate from home using your smartphone for 2-6 weeks after delivery.
La Jolla, CaliforniaAges 18 years+ - NCT06064097RecruitingPhase 2
Nivolumab plus chemo for young people with nasopharyngeal cancer
This trial tests combining the immunotherapy drug nivolumab with standard chemotherapy to treat newly diagnosed nasopharyngeal cancer in children and young adults. The goal is to see if adding this immune-boosting medicine can help shrink tumors and prevent the cancer from coming back.
Downey, CaliforniaAges Up to 21 years - NCT07290478Enrolling by invitation
Helping You Choose a Health Care Proxy
This study helps you name someone to make health decisions for you if you can't. It's for older adults or people with serious conditions, and it aims to make this important choice easier.
Martinez, CaliforniaAges 18 years+ - NCT06969755RecruitingPhase 4
Brain scans and genetics to guide early schizophrenia treatment
This study tests whether using brain scans and genetic tests can help choose the best treatment for people early in their schizophrenia. It will check if these biomarkers can predict who will respond better to medication.
La Jolla, CaliforniaAges 18–35 - NCT07524946RecruitingPhase 4
Safety and effectiveness of Cabtreo for moderate to severe acne
This study tests a new acne treatment called Cabtreo in children and young teens ages 9–11. The treatment combines three ingredients to reduce acne bumps and spots on the face and body.
Freemont, CaliforniaAges 9–11 - NCT07730268Enrolling by invitation
Vivio at-home study for heart failure monitoring
This study tests a home monitoring device (Vivio) for people who already have a CardioMEMS implant to check if the new device can track your heart health easily at home.
Long Beach, CaliforniaAges 21 years+ - NCT03258658RecruitingPhase 1
Testing a personalized urethra repair made from your own tissue
This early study tests whether an engineered urethral patch made from your own body tissue is safe and workable for urethral strictures (narrowing that blocks urine flow). It is mainly looking for safety and how feasible the procedure and follow-up are, not proven cure yet.
San Francisco, CaliforniaAges 21–75 - NCT07717723Recruiting
Support for caregivers of heart disease patients
This study tests a program to help caregivers of people with heart disease manage stress and challenges. It aims to support your mental health while caring for a loved one.
Sacramento, CaliforniaAges 18 years+ - NCT06843577Recruiting
Handgrip therapy for high blood pressure
This trial tests if a simple handgrip exercise device can help lower blood pressure in people with elevated blood pressure or hypertension. You will use the device at home and have regular check-ups to see how well it works.
Valley Village, CaliforniaAges 22 years+ - NCT07391904Enrolling by invitation
Testing lab result communication for older adults
This study tests a tool designed to help older adults understand their lab results more easily. Researchers want to see if the tool improves patient understanding and engagement.
Los Angeles, CaliforniaAges 65 years+ - NCT06188689Recruiting
Testing a new diagnostic test for heart rhythm disorders
This study is evaluating a new diagnostic test for Calcium Release Deficiency Syndrome (CRDS) and related heart rhythm disorders. It aims to find out if this test can accurately identify patients with these conditions, which could lead to better diagnosis and treatment.
San Francisco, CaliforniaAges Any age - NCT07428538RecruitingPhase 3
Testing larsucosterol for severe alcohol-related hepatitis
This trial tests a new medicine called larsucosterol to see if it helps people with severe alcohol-related hepatitis (liver inflammation from heavy drinking). If you qualify, the study will monitor your safety and recovery over 90 days.
Coronado, CaliforniaAges 18 years+ - NCT06177717Recruiting
Lung Health Study for Young Adults
This study looks at how young adults' lungs work over time. It is a research visit where you'll complete breathing and other health tests to help understand lung health in people aged 25–35.
Los Angeles, CaliforniaAges 25–35 - NCT05145491Recruiting
Immediate or delayed surgery for vision changes from ERM
This trial compares doing ERM surgery right away versus waiting at least 4 weeks to see if your vision stays stable. It may help people decide the safest timing for surgery when the membrane in the retina (ERM) is causing symptoms.
Glendale, CaliforniaAges 50 years+ - NCT05844982RecruitingPhase 3
Eye injections or steroid implant to prevent vision loss
This trial studies ways to prevent worsening vision caused by radiation damage to the retina after plaque brachytherapy for uveal melanoma. You may be randomly assigned to a medication injection, a steroid implant, or observation to see which approach best protects vision.
Palo Alto, CaliforniaAges 18 years+ - NCT07022678RecruitingPhase 3
Xylitol dental wipes to reduce infection risk in childhood leukemia
This trial tests whether using xylitol dental wipes can lower the risk of bloodstream infections in children with acute myeloid leukemia (AML) who are receiving chemotherapy. If you or your child have AML and will have at least two cycles of chemo that include cytarabine, this study may help reduce infection risk.
Madera, CaliforniaAges 1–25 - NCT03388606Recruiting
Studying adolescent depression and how to treat it
This study looks closely at how depression shows up in teens and tests approaches to treatment. It may help teens and families better understand depression and get access to structured care as part of research.
Los Angeles, CaliforniaAges 11–25 - NCT03463954Recruiting
Laser treatment trial for small breast tumors
This trial tests a focused laser treatment (Novilase®) to destroy small, cancerous breast tumors while aiming to work with standard care. It may help people who have an early, localized tumor that can be clearly seen on imaging so doctors can guide the laser safely.
Rancho Mirage, CaliforniaAges 18 years+ - NCT03774758Recruiting
Blood tests to estimate lung cancer risk over 3 years
This study looks for blood “biomarkers” (measurable signs in blood) that may help predict who is at higher or lower risk related to lung cancer. You would have blood samples taken and then be followed with visits for up to 3 years.
San Francisco, CaliforniaAges 40 years+ - NCT03968393RecruitingPhase 4
Blood thinner to prevent stroke after stress-related irregular heartbeats
This trial tests whether taking a blood thinner can lower the risk of stroke in people who had atrial fibrillation (an irregular heartbeat) that happened temporarily around a stressful illness or surgery. It looks especially at people at higher risk for stroke after that episode.
Los Angeles, CaliforniaAges 55 years+ - NCT03987763RecruitingPhase 4
Study of psoriasis lotion safety in children ages 6–16
This trial tests how safe and how the body handles (pharmacokinetics) a psoriasis lotion called IDP-122 when used in children with plaque psoriasis. You may be able to join if your child has a suitable amount of plaque psoriasis and can follow safety rules during the study.
Fountain Valley, CaliforniaAges 6–17 - NCT04005976Recruiting
Genetic study for inherited aortic disease
This trial is for people with inherited (family-run) aortic enlargement or aneurysm caused by a specific DNA gene change. It uses genetic information to guide more precise care, which may help tailor monitoring and treatment for you and your family.
Newport Beach, CaliforniaAges Any age - NCT05524597RecruitingPhase 1
Older adults write about health experiences
This study looks at how writing about your life experiences and health affects outcomes in older adults. If you’re 65 or older and meet health and safety requirements, you may be able to take part.
Los Angeles, CaliforniaAges 65 years+
Where these studies are running in California
Institutions with a site for the recruiting health studies listed above.
- University of California San Diego Health · 3 studies
- University of California, Davis Medical Center · 3 studies
- University of California, Los Angeles (UCLA) · 3 studies
- University of California, San Francisco · 3 studies
- Cedars-Sinai Medical Center · 2 studies
- Kaiser Permanente-Oakland · 2 studies
- University of Southern California · 2 studies
- Valley Children's Hospital · 2 studies
What taking part in a health study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Common questions
- Are there health clinical trials in California?
- Yes. We're currently tracking 341 recruiting health studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a health study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a health trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New health studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.