Clinical trials · California
Health clinical trials in California
We’re tracking 342 recruiting health studies with a site in California — including Early Phase 1, Phase 1, Phase 2 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07717723Recruiting
Support for caregivers of heart disease patients
This study tests a program to help caregivers of people with heart disease manage stress and challenges. It aims to support your mental health while caring for a loved one.
Sacramento, CaliforniaAges 18 years+ - NCT07694544RecruitingPhase 1
Oral EC5026 study in people with kidney disease
This trial tests a medication called EC5026 in people with and without chronic kidney disease (CKD) to see how the body handles it. It helps understand if dose adjustments are needed for people with impaired kidney function.
Sacramento, CaliforniaAges 55 years+ - NCT07694206Recruiting
Digital and blood tests for delirium in the ICU
This trial studies whether digital tools and blood tests can help detect delirium (sudden confusion) in ICU patients. If you or your loved one is in the ICU, this research could lead to better monitoring and care.
La Jolla, CaliforniaAges 65 years+ - NCT07686913Recruiting
Steri-Strips vs standard closure for C-section incisions
This study compares using Steri-Strips (a special type of tape) to close the C-section incision versus the standard method. The goal is to see which way helps the wound heal better.
Moreno Valley, CaliforniaAges 18 years+ - NCT07675109Recruiting
Extended therapy for restless legs syndrome
This study tests a device that delivers nerve stimulation to help with restless legs syndrome (RLS). It aims to see if using the device for a longer period each night can reduce RLS symptoms and improve sleep.
Pleasanton, CaliforniaAges 21 years+ - NCT07675590RecruitingPhase 1
Safety study of TIX100 in healthy volunteers
This study tests a new oral medication called TIX100 in healthy people to see if it is safe and how the body handles it. It is the first step in human testing, so it focuses on safety and side effects.
Chula Vista, CaliforniaAges 18–70 - NCT07673172Enrolling by invitation
Heart Health Program for Teens and Young Adults with Autism
This trial tests a two-part program to improve heart health in people with autism who are above a healthy weight. It may help you learn ways to take better care of your heart.
Los Angeles, CaliforniaAges 9–26 - NCT07657988Recruiting
Tirbanibulin for actinic keratosis on the face
This study tests a cream called tirbanibulin (Klisyri) for adults with 4 to 12 actinic keratosis (AK) spots on their face. It aims to see how well the treatment works when applied to a larger area of the face in everyday medical practice.
Manhattan Beach, CaliforniaAges 18 years+ - NCT07642414Enrolling by invitation
Digital program combining exercises and mindfulness for migraines
This 12-week online program uses exercises, mindfulness, and digital tracking to help reduce migraines. You'll work with the app on your smartphone while staying on your current migraine medications.
San Francisco, CaliforniaAges 18 years+ - NCT07641413Recruiting
Lung and heart health across decades in veterans
This study looks at how lungs and hearts work in healthy veterans over time. If you have no major health conditions, you may help researchers learn how these organs age naturally.
San Francisco, CaliforniaAges 24–68 - NCT07631442Enrolling by invitation
Digital Health Monitoring for Primary Biliary Cholangitis
This study uses a smartphone app or digital platform to track how you're feeling day-to-day if you have primary biliary cholangitis (PBC), a liver condition where your immune system damages bile ducts. Researchers want to see if this digital monitoring helps them better understand and manage PBC symptoms.
Redwood City, CaliforniaAges 18 years+ - NCT07606625RecruitingPhase 4
Nasal spray for dry eye disease and tear film stability
This study tests whether a nasal spray can improve dry eye symptoms and tear production in people with mild to moderate meibomian gland dysfunction (a common cause of dry eye). You'll use the spray daily while the research team monitors your eye health and comfort over several weeks.
Berkeley, CaliforniaAges 18 years+ - NCT07609394Recruiting
Duchenne and Becker Muscular Dystrophy Health Records Study
This study collects electronic health records (medical information already in your doctor's computer system) from people with Duchenne or Becker muscular dystrophy, or female carriers of these conditions. Researchers will use this data to better understand the diseases and improve care over time.
Sacramento, CaliforniaAges Any age - NCT05986279Recruiting
MINDGAPS: A balance and mental health study for military members
This study tests a program called MINDGAPS to help Veterans and active-duty service members with their balance and mental health. If you are a military member who can stand on your own and have not had a recent head injury, you may be eligible.
San Diego, CaliforniaAges 18 years+ - NCT07580222Recruiting
Using Mobile Technology to Track Knee Arthritis Health
This study uses smartphone or tablet technology to measure how your knee osteoarthritis (wear-and-tear arthritis) changes over time. You'll be helping researchers understand how well a previous arthritis treatment works by tracking your knee health at home.
Palo Alto, CaliforniaAges 30 years+ - NCT07582848Recruiting
Breastfeeding Support for Babies with Heart Disease
This study helps mothers of babies born with heart defects learn to breastfeed directly, even when the baby needs heart surgery in the first month of life. Researchers want to see if direct breastfeeding improves health outcomes for both mother and baby during this critical time.
Los Angeles, CaliforniaAges 18 years+ - NCT07577947Recruiting
Digital tracking to help treat pregnancy and postpartum depression
This study tests whether wearing an Apple Watch and using a smartphone app can help doctors better understand and treat depression during pregnancy and after birth. You'll receive depression treatment through the study while the app and watch track your daily patterns.
Los Angeles, CaliforniaAges 18 years+ - NCT07565753RecruitingEarly Phase 1
Testing a medication to stop bleeding after tonsil removal
This study tests a medicine called tranexamic acid to help stop bleeding in children who had their tonsils removed and are now bleeding more than a day after surgery. Researchers want to see if this medicine can reduce the amount of bleeding and help children recover faster.
Davis, CaliforniaAges 2–17 - NCT07561541RecruitingPhase 4
Extended Antibiotics for Diabetic Leg Fracture Surgery
This study tests whether taking antibiotics for a longer time helps prevent infections in people with poorly controlled diabetes who need surgery for a lower leg or foot fracture. Since diabetes makes infections more likely after surgery, extra antibiotics might reduce that risk.
Los Angeles, CaliforniaAges 18 years+ - NCT06738537Recruiting
Choosing treatment for mitral valve prolapse
This study looks at how to involve you in decisions about treating mitral valve prolapse, a condition where a heart valve doesn't close tightly. It aims to find the best way to help you and your doctor choose the right treatment.
Los Angeles, CaliforniaAges 21 years+ - NCT07559175RecruitingPhase 2
A new enzyme treatment for pancreatic insufficiency
This study tests a new pancreatic enzyme medicine (called NHS7108) for people with exocrine pancreatic insufficiency (EPI). EPI means your pancreas doesn't make enough enzymes to break down food properly. The study aims to see if this new medicine is safe and works well to help your body absorb nutrients.
Los Angeles, CaliforniaAges 18–85 - NCT07552311Recruiting
Fitbit AI Care Planning Study
This study tests a new artificial intelligence tool designed to help create personalized health plans using your Fitbit data and Google account. Researchers want to learn if this AI-powered planning tool can help you better manage your health.
Mountain View, CaliforniaAges 18 years+ - NCT07549178Recruiting
Mobile monitoring and care coordination for serious mental illness
This study tests whether combining extra care coordination with tracking data from your smartphone can help improve mental health care and reduce hospital visits. Researchers will use your smartphone to monitor your wellbeing while a care coordinator helps connect you with the support you need.
West Los Angeles, CaliforniaAges 18 years+ - NCT07528014Recruiting
Tracking Depression Treatment Outcomes Over Time
This study follows adults receiving depression treatment (esketamine, TMS, or SAINT) to understand how these therapies work and their effects over time. Researchers will assess mood, functioning, and other factors to help improve future treatment.
La Jolla, CaliforniaAges 18 years+
Where these studies are running in California
Institutions with a site for the recruiting health studies listed above.
- Cedars-Sinai Medical Center · 2 studies
- UC Davis Health · 2 studies
- 1100 Glendon Ave
- Ablon Skin Institute and Research Center
- Children's Hospital of Los Angeles
- Google LLC
- Hinge Health, Inc.
- Keck Medicine of USC
What taking part in a health study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Common questions
- Are there health clinical trials in California?
- Yes. We're currently tracking 342 recruiting health studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a health study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a health trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New health studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.