Clinical trials · California
Health clinical trials in California
We’re tracking 341 recruiting health studies with a site in California — including Early Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT03085875Recruiting
Healthy Pregnancy Study for Moms Using Phone Apps
This study looks at healthy pregnancy habits and support for expecting moms (and moms up to 8 weeks after delivery) through a research community. It may help you compare or improve health behaviors with guidance and study activities delivered on your phone or tablet.
La Jolla, CaliforniaAges 16 years+ - NCT02825654Enrolling by invitation
Deployed Veterans Study of Service and Health
This study looks at how military service and deployment experiences relate to health and wellbeing in veterans who served after 9/11. It may help researchers understand which factors affect long-term health.
San Diego, CaliforniaAges Any age - NCT07437911Recruiting
Can a Supplement Help with Nutrient Gaps for GLP-1 Users?
This study tests whether a daily supplement can help fill nutrient gaps and improve gut health for people who are already taking GLP-1 weight-loss medications (like Ozempic or Wegovy). Participants must be on a stable dose for at least 8 weeks and be generally healthy without other chronic conditions.
Santa Monica, CaliforniaAges 18–59 - NCT06249126Recruiting
Heel bone fusion for severe fractures
This trial tests whether fusing the joint just below the ankle (subtalar joint) during heel bone fracture repair helps people with severe fractures heal better. You may qualify if you have a specific type of broken heel bone and can return for follow-up visits for one year.
Orange, CaliforniaAges 18 years+ - NCT07577947Recruiting
Digital tracking to help treat pregnancy and postpartum depression
This study tests whether wearing an Apple Watch and using a smartphone app can help doctors better understand and treat depression during pregnancy and after birth. You'll receive depression treatment through the study while the app and watch track your daily patterns.
Los Angeles, CaliforniaAges 18 years+ - NCT07565753RecruitingEarly Phase 1
Testing a medication to stop bleeding after tonsil removal
This study tests a medicine called tranexamic acid to help stop bleeding in children who had their tonsils removed and are now bleeding more than a day after surgery. Researchers want to see if this medicine can reduce the amount of bleeding and help children recover faster.
Davis, CaliforniaAges 2–17 - NCT07441083Recruiting
Shatavari root extract for women's sexual wellness
This trial tests if a herbal supplement called Shatavari can help improve sexual desire and function in women who feel stressed. You would take the supplement daily and report how you feel over several weeks.
San Francisco, CaliforniaAges 20–50 - NCT06410209RecruitingPhase 2
Walking Juntos: Smartphone program to help Hispanic cancer survivors be active
This study will test if a smartphone program and social media group can help Hispanic/Latino teens and young adults who had childhood cancer become more physically active. You would wear a Fitbit and use a phone app with culturally tailored tips and support.
Downey, CaliforniaAges 15–20 - NCT07511088Recruiting
Study of a supplement for mild stress in healthy adults
This study tests a dietary supplement for people who experience mild stress or anxiety at least once a week. You will fill out surveys on your phone or computer to see if the supplement helps you feel calmer.
San Francisco, CaliforniaAges 18–60 - NCT06631365RecruitingPhase 2
PrEP on demand: a pilot study for men who have sex with men
This study tests a '2-1-1' on-demand PrEP strategy for cisgender men who have sex with men. It aims to see if taking PrEP only around the time of sex is safe and effective. If you are interested in starting or currently taking PrEP this way, you may be eligible.
San Francisco, CaliforniaAges 18 years+ - NCT07451106Recruiting
Wearable bladder sensor for pelvic health therapy
This trial tests whether a wearable sensor for the bladder can help guide pelvic health physical therapy. It is designed for people who are already referred to pelvic PT, including postpartum women and men who have had prostate surgery.
San Francisco, CaliforniaAges 18 years+ - NCT07420205RecruitingPhase 2
Sleep health study for U.S. Marines
This study looks at the sleep health of active-duty U.S. Marines. If you join, researchers will check your sleep patterns and may offer ways to improve your rest.
San Diego, CaliforniaAges 18 years+ - NCT05772130Recruiting
Help family members get cancer genetic test results and counseling
This study tests a family-centered way to share cancer genetic testing results with close relatives, so more relatives get genetic counseling and testing. It may help your eligible family members understand their risk and get the right next steps.
Duarte, CaliforniaAges 18 years+ - NCT06790784RecruitingPhase 3
Comparing faricimab plus laser vs. surgery for diabetic eye disease
This study compares two approaches to treat advanced diabetic eye disease (proliferative diabetic retinopathy): injections of faricimab plus laser, versus surgery (vitrectomy) with laser. It is for people with diabetes who need treatment for PDR and still have relatively good vision (20/100 or better) in the affected eye.
Huntington Beach, CaliforniaAges 18 years+ - NCT07204249RecruitingPhase 2
Testing a diabetes drug to help stop meth use
This study tests whether a medication called 'Glutide' (a GLP-1 agonist, similar to drugs used for diabetes) can help people who want to stop or cut down on methamphetamine. It's for those with moderate to severe meth use disorder who have used meth on at least 15 of the past 30 days.
San Francisco, CaliforniaAges 18–65 - NCT07268404Recruiting
Women's Hormonal and Metabolic Health Study
This trial tests a program to help women with irregular periods and hormonal imbalance symptoms like mood swings or skin issues. You'll track your symptoms and provide blood samples from home to see if the program improves your health.
San Francisco, CaliforniaAges 18–45 - NCT07142044RecruitingPhase 1/Phase 2
Testing EC5026 for Parkinson's disease
This study tests a new oral medication called EC5026 for Parkinson's disease. It aims to see if the drug is safe and if it might help control symptoms when added to your current levodopa treatment.
Sacramento, CaliforniaAges 50–80 - NCT04096586Recruiting
Study tests how watermelon affects fullness and digestion
This study looks at whether eating watermelon changes how full you feel and how your digestion works. It’s for generally healthy people and skips those with certain health factors or who can’t eat watermelon safely.
San Diego, CaliforniaAges 10–55 - NCT06590285Recruiting
Better ways to manage bone marrow transplant care
This study tests a smartphone app to help patients and doctors manage care during a bone marrow transplant. If you are planning a transplant, the app may give you clear guidance and education.
San Diego, CaliforniaAges 18 years+ - NCT05786664Recruiting
Breast cancer survivor study collecting your health samples
This study invites women who finished treatment for non-metastatic invasive breast cancer to share health information and biological samples for future research. It may help scientists understand survivorship and improve care after treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT05008848RecruitingPhase 3
Text message program to help rural cancer survivors quit smoking
This trial studies a text-message based program to help people who smoke quit. It targets adults in rural areas who are currently in cancer treatment and want support stopping smoking.
St. Helena, CaliforniaAges 18 years+ - NCT06513962RecruitingPhase 3
Triptorelin to protect ovaries in young women with cancer
This study tests whether a medicine called triptorelin can protect the ovaries in young women and teens receiving strong chemotherapy for cancer. If you are newly diagnosed with a cancer (other than breast cancer) and are about to get certain chemotherapy drugs, this trial may help preserve your fertility.
Duarte, CaliforniaAges Up to 39 years - NCT06459206Recruiting
Testing a smart ring's oxygen sensor during low oxygen levels
This study checks how well a special ring (EvieMED Ring) measures oxygen in your blood when oxygen levels are made very low in a controlled setting. It helps see if the ring is accurate for people with serious health conditions.
San Francisco, CaliforniaAges 18–49 - NCT07332312Recruiting
Cancer support program for American Indian and Alaska Native patients in rural California
This study tests a culturally informed patient navigation program designed to help American Indian and Alaska Native cancer patients reduce delays between diagnosis and treatment. It offers support through community advisors, focus groups, and a navigation program tailored to patients living in the Toiyabe Indian Health Program service area.
Bishop, CaliforniaAges Any age
Where these studies are running in California
Institutions with a site for the recruiting health studies listed above.
- City of Hope Comprehensive Cancer Center · 3 studies
- University of California, Los Angeles (UCLA) · 3 studies
- Alethios, Inc. · 2 studies
- Kaiser Permanente-Oakland · 2 studies
- Rady Children's Hospital San Diego · 2 studies
- San Diego State University · 2 studies
- University of California, San Francisco · 2 studies
- USC / Norris Comprehensive Cancer Center · 2 studies
What taking part in a health study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Common questions
- Are there health clinical trials in California?
- Yes. We're currently tracking 341 recruiting health studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a health study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a health trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New health studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.