Clinical trials
Hemophilia A clinical trials
Below are recruiting hemophilia a clinical trials, each written for real people, not researchers. We’re tracking 92 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06809972Recruiting
Understanding joint lining changes on ultrasound in hemophilia
This study uses ultrasound to check if thickened joint lining (synovium) in people with severe hemophilia is a sign of active inflammation or just a harmless leftover. It may help doctors decide whether to treat or watch these joints.
UtrechtAges 12 years+ - NCT06833983RecruitingPhase 3
Study of GS1191-0445 injection for hemophilia A
This trial tests a new injection called GS1191-0445 for people with hemophilia A. It aims to see if it is safe and works well to prevent or treat bleeding episodes.
Hefei, AnhuiAges 18–65 - NCT06864975RecruitingPhase 4
Different doses of ADVATE for immune tolerance in boys with hemophilia A and inhibitors
This trial tests how different doses and schedules of the factor VIII medicine ADVATE can train the immune system to accept factor VIII again in boys with hemophilia A who have developed inhibitors. The goal is to find a better way to help their bodies stop blocking the treatment.
Beijing, Beijing MunicipalityAges birth–18 years - NCT06992076Recruiting
Hemophilia patients' experience with marstacimab treatment
This registry study follows people with hemophilia A or B who are taking marstacimab as their regular preventive treatment. It aims to understand how the medicine works in real life and how patients feel during treatment.
Xiamen, FujianAges 12 years+ - NCT07099313Recruiting
Hemophilia treatment burden and daily life study
This study looks at how prophylactic treatment for hemophilia affects your daily life, sleep, and feelings about your health. It compares different types of clotting factor concentrates to see if one is easier to manage than the other.
Oviedo, Principality of AsturiasAges 18 years+ - NCT07101926Recruiting
Monitoring anti-TFPI in severe hemophilia patients on Marstacimab
This study looks at how a medicine called Marstacimab affects your body's natural anti-clotting protein (TFPI) in people with severe hemophilia A or B who are already taking it. It involves blood tests to see how well the treatment works.
BronAges 18 years+ - NCT05022459Recruiting
Prevent bleeding in kids with Hemophilia A who play sports
This study compares two ways to prevent bleeding in people with Hemophilia A while they play sports. It looks at whether factor VIII or emicizumab prophylaxis helps reduce bleeding during higher-risk sports activities.
Little Rock, ArkansasAges 6–19 - NCT07285460RecruitingPhase 3
Fitusiran for young boys with hemophilia A or B
This trial tests if fitusiran, given as a shot, can help prevent bleeding in boys ages 1 to 12 with severe hemophilia (factor VIII under 1% or factor IX at 2% or lower). It includes boys with or without inhibitors and aims to understand safety and how well it works.
Los Angeles, CaliforniaAges 1–11 - NCT07314983Recruiting
Long-term blood thinning in severe hemophilia A
This study looks at using long-term blood thinners (anticoagulants) in adults with severe hemophilia A, a bleeding disorder. It aims to understand if this treatment can be safe and effective for patients who may need it.
StrasbourgAges 18 years+ - NCT07406139RecruitingPhase 4
PCC treatment for hemophilia A with inhibitors
This trial tests a clotting factor product called PCC (prothrombin complex concentrate) to treat bleeding episodes in people with hemophilia A who have developed inhibitors. It's for those who are 12–65 and have frequent joint bleeds.
Tianjin, Tianjin MunicipalityAges 12–65 - NCT07523399Recruiting
Joint Health and Balance in Adults with Hemophilia A
This study looks at how hemophilia A affects joint health, balance, and quality of life in adults. Researchers will assess your joints and balance to understand the relationship between joint damage and everyday function.
VanAges 18–65 - NCT07579585Recruiting
Light therapy for knee bleeding in hemophilia children
This study tests whether a special type of light therapy (photobiomodulation) can help reduce pain and swelling in the knees of children with hemophilia who experience bleeding into the joint. Hemophilia is a bleeding disorder where blood doesn't clot properly.
Sialkot, Punjab ProvinceAges 9–14 - NCT07259356Enrolling by invitation
Blood-flow-restriction training for hemophilia patients
This trial tests whether a special type of exercise that limits blood flow is safe and possible for people with hemophilia. It might help strengthen muscles without causing joint bleeds.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT06816953Enrolling by invitation
Joint health in severe hemophilia A with prophylaxis
This study is looking at how well joint health can be tracked in people with severe hemophilia A who are receiving regular factor VIII treatment. It uses special markers in the blood and ultrasound to check for early joint changes.
Bangkok, PatumwanAges Any age - NCT05962398Enrolling by invitation
Follow-up study for men previously treated with CSL222
This study checks long-term safety and outcomes in men with hemophilia B who previously received CSL222. It may help your care team better understand how well the treatment lasts over many years.
Phoenix, ArizonaAges 18 years+ - NCT05768386Enrolling by invitation
Long-term follow-up for severe hemophilia A after BMN 270 study
This study checks how people with severe hemophilia A are doing over time after joining a previous BioMarin study of BMN 270. It helps researchers understand long-term safety and outcomes and may support your ongoing care plan.
Los Angeles, CaliforniaAges 18 years+ - NCT06461533Recruiting
A survey of susoctocog alfa for acquired hemophilia A
This trial is studying a medication called susoctocog alfa for people with acquired hemophilia A, a bleeding disorder. It aims to understand how well the treatment works and how it is being used.
Tokyo, TokyoAges Any age - NCT03797495Recruiting
Study for people with low plasminogen or their close family
This study looks at people diagnosed with type 1 plasminogen deficiency (a condition with low plasminogen levels) and can also include their first-degree family members. It may help researchers learn more about the condition and how to monitor it over time by collecting blood and genetic information.
Birmingham, AlabamaAges Any age - NCT07681089RecruitingPhase 2
Foscenvivint for HIV/HCV cirrhosis with hemophilia
This trial tests a drug called foscenvivint for people with hemophilia and liver cirrhosis caused by both HIV and hepatitis C (already treated). The study aims to see if it can help improve liver health.
Sapporo, HokkaidoAges 18–79 - NCT07723560Recruiting
Surgery study for hemophilia A patients using Altuvoct
This study looks at how people with hemophilia A do when they have surgery while using the medicine Altuvoct (efanesoctocog alfa). It helps doctors learn more about surgical practices for this condition.
BronAges Any age - NCT03549858Recruiting
Survey study on burdens and experiences of people with hemophilia
This study collects information from people with hemophilia about how treatments and daily life affect them. It uses your answers to improve patient-focused care and understand what challenges matter most.
Hamilton, OntarioAges Any age - NCT03961243RecruitingPhase 1
Gene therapy for hemophilia B using a FIX gene treatment
This trial tests a one-time (or limited) gene therapy meant to help the body make more factor IX (FIX), which can reduce bleeding in people with hemophilia B. You may be able to qualify if you have significant bleeding history, no factor IX “blockers” (inhibitors), and can follow strict safety and pregnancy-prevention rules.
Shenzhen, GuangdongAges 2–65 - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Phoenix, ArizonaAges birth–20 years - NCT04398628Recruiting
Study of non-cancer blood disorders in people with bleeding or clotting
This study follows people with inherited or acquired non-cancer blood disorders to better understand symptoms, causes, and how different treatments work over time. You may be placed into a disorder-specific group, depending on your diagnosis and testing results.
Phoenix, ArizonaAges Any age
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Common questions
- Are there clinical trials for hemophilia a?
- Yes. Clin2 currently lists 92 recruiting hemophilia a studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hemophilia a trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hemophilia a trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.