Clinical trials
High Cholesterol clinical trials
Below are recruiting high cholesterol clinical trials, each written for real people, not researchers. We’re tracking 12 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07220213Recruiting
Fellowship to better health for Black men
This study tests a program to help Black men improve their heart health. It focuses on lifestyle changes like diet and physical activity.
Birmingham, AlabamaAges 18 years+ - NCT07428473RecruitingPhase 1
Study of STX-1150 for high cholesterol
This early-phase trial tests a new medication called STX-1150 for people with high LDL cholesterol. It aims to see if the drug is safe and how well it works to lower cholesterol.
Clayton, VictoriaAges 18–70 - NCT06471036Recruiting
Improving cholesterol testing and treatment after a heart attack
This study tests whether giving extra education to doctors and patients can help improve cholesterol management after a heart-related hospitalization. It aims to see if a simple program can make sure patients get the right testing and treatment for high cholesterol.
Minneapolis, MinnesotaAges 18 years+ - NCT05693701Recruiting
Lifestyle and study program for blood donors with high cholesterol
This study tests a multicomponent program for people who donate blood and have high cholesterol that fits familial hypercholesterolemia criteria. It may help lower cholesterol, but you must not already be on cholesterol-lowering medicines.
Dallas, TexasAges 18–75 - NCT06192251Recruiting
Lifestyle medicine program for chronic conditions
This trial tests a complete lifestyle medicine program to help people with conditions like prediabetes, diabetes, high blood pressure, heart disease, high cholesterol, or being overweight. The program aims to improve your overall health through diet, exercise, and other lifestyle changes.
Parry Sound, OntarioAges 18 years+ - NCT07126587Recruiting
Healthy Living in Anson County Study
This study offers healthy meals and group classes to help people in Anson County manage or prevent chronic diseases like diabetes and high blood pressure. You'll learn about and try a Mediterranean diet, which is known to be good for heart health.
Chapel Hill, North CarolinaAges 18–99 - NCT07347678RecruitingPhase 1
Safety study of RN5681 in healthy volunteers
This trial tests a new drug called RN5681 to see if it is safe and how the body processes it. It is for healthy people with certain cholesterol levels and may help people with high cholesterol or heart risk in the future.
Brisbane, QueenslandAges 18–65 - NCT06422741Recruiting
Grape seed extract for cholesterol in night shift workers
This study tests whether a grape seed extract supplement can help lower LDL (bad) cholesterol in people who work rotating night shifts. It is looking for healthy adults with moderately high cholesterol who are not taking cholesterol medicine.
Reus, TarragonaAges 18 years+ - NCT03770312RecruitingPhase 4
Testing low/moderate statin use to prevent heart problems in older adults
This study looks at whether taking a low- to moderate-dose statin can prevent first-time heart and stroke problems in people age 70 and older. It may help you lower “bad cholesterol” (LDL) and see if that leads to fewer heart events over time.
SeoulAges 70 years+ - NCT06988462Recruiting
Bottarga supplement for metabolic health
This study tests a supplement called bottarga, made from fish eggs, to see if it improves cholesterol, blood sugar, or weight in people with metabolic problems like high cholesterol or prediabetes. It is a small pilot study for Massachusetts residents.
Sommerville, MassachusettsAges 18–60 - NCT04798430Enrolling by invitationPhase 3
Study drug follow-up for LDL reduction in high-risk cholesterol patients
This Phase 3 study looks at the long-term safety and benefit of OLE LIB003 for people with very high cholesterol or heart disease risk who still need lower LDL (“bad cholesterol”). It’s likely a continuation study for participants who already did earlier LIB003 Phase 3 trials.
Evanston, IllinoisAges 10 years+ - NCT07252830Recruiting
Finding hidden heart risk with extra imaging tests
This study looks at whether using special scans of the heart and neck arteries can better find people at very high risk for heart problems, compared to just using a standard risk score. You may be eligible if you have high cholesterol and are seeing a heart doctor.
PoitiersAges 40–80
Hear when a new High Cholesterol trial opens
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Common questions
- Are there clinical trials for high cholesterol?
- Yes. Clin2 currently lists 12 recruiting high cholesterol studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high cholesterol trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high cholesterol trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.