Clinical trials · California
HIV clinical trials in California
We’re tracking 66 recruiting hiv studies with a site in California — including Phase 1 and Phase 1/Phase 2 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07467018Recruiting
Mobile van study of a long-acting HIV prevention shot
This study tests if giving a long-acting HIV prevention shot (lenacapavir) from a mobile medical van can reach people at risk for HIV in Los Angeles County. You may be able to join if you are HIV negative, at risk for HIV, and are willing to try a shot instead of a daily pill.
Santa Monica, CaliforniaAges 18 years+ - NCT07433985Recruiting
California mobile app study for men after jail release
This study tests a mobile app to help men recently released from jail or prison who use drugs or have sex with men stay healthy and avoid HIV. It's for people who don't have HIV and live in certain California counties.
Oakland, CaliforniaAges 18–59 - NCT07181486RecruitingPhase 1
Safety study of a vaginal gel for healthy women
This trial tests a gel placed in the vagina to see if it is safe. Healthy women with regular periods who have a steady partner may join.
San Francisco, CaliforniaAges 18–45 - NCT07125235Recruiting
Support program for HIV treatment adherence
This trial tests a program to help people with HIV stay on track with their medication. If you take HIV medication, sometimes miss doses, and use stimulants, this program may offer support to improve your health.
San Francisco, CaliforniaAges 18–70 - NCT07089836Recruiting
Syphilis blood test study for at-risk and healthy people
This study tests two new blood tests for syphilis. It compares them to approved tests using blood from people who may have or had syphilis, including pregnant women, HIV-positive people, and healthy volunteers.
Lancaster, CaliforniaAges 13 years+ - NCT07087145Recruiting
HPV test by mail for men with HIV
This trial explores if mailing an HPV self-test kit to your home is a good way to screen for HPV. It's for men over 35 who have sex with men, including trans women, and are living with HIV.
San Francisco, CaliforniaAges 35 years+ - NCT07040319RecruitingPhase 1/Phase 2
Hepatitis C treatment study for pregnant women
This study tests a medicine called glecaprevir/pibrentasvir for pregnant women with hepatitis C, with or without HIV. It aims to see how the medicine works in the body and if it is safe during pregnancy.
Los Angeles, CaliforniaAges 16–45 - NCT06665646RecruitingPhase 1
HIV vaccine booster study for previous trial participants
This study tests a booster vaccine for HIV in people who were part of an earlier HIV vaccine trial. The goal is to see if it's safe and helps the immune system fight HIV better.
San Francisco, CaliforniaAges 18–60 - NCT06444360Recruiting
Program to reduce stimulant use and risky sex in young adults
This study tests a program to help sexually active young adults reduce stimulant use and risky sexual behavior. It involves online coaching sessions, and you can join from home if you have a private space and video chat access.
Los Angeles, CaliforniaAges 16–24 - NCT06388109Recruiting
Lifesaving support app for HIV care
This trial tests a mobile app designed to help people living with HIV stay engaged in their care. If you are newly diagnosed, have missed appointments, or have had trouble keeping your viral load suppressed, this app could provide the support you need to stay healthy.
Van Nuys, CaliforniaAges 13–34 - NCT06343311RecruitingPhase 1/Phase 2
T-cell therapy for adults with relapsed or refractory B-cell lymphoma
This trial tests a new T-cell therapy (EB103) for people with B-cell non-Hodgkin's lymphoma that has come back or stopped responding to treatment. It aims to see if the therapy is safe and effective.
Sacramento, CaliforniaAges 18 years+ - NCT06216600Recruiting
Women's strength and resilience program for HIV and substance use
This study tests a program for women living with HIV who also struggle with substance use or heavy drinking. It combines exercise and support to help build strength and resilience. You may qualify if you've missed some HIV medications, have a detectable viral load, and have experienced violence.
San Diego, CaliforniaAges 18 years+ - NCT06128304Recruiting
Cervical cancer screening for women with HIV
This trial offers quick cervical cancer screening and treatment for women living with HIV, aiming to prevent cancer and improve health.
La Jolla, CaliforniaAges 25–64 - NCT05509959Recruiting
Tech-based peer support for women with HIV and low adherence
This study tests a phone/computer-based peer support program to help women with HIV improve how consistently they take their HIV medicine (ART). It may help if you’ve had trouble meeting your medication schedule recently and you’re eligible to safely participate.
La Jolla, CaliforniaAges 18 years+ - NCT05866523Recruiting
Help for people newly diagnosed with HIV
This study is for adults who were recently diagnosed with HIV and are not yet on HIV treatment (ART). It aims to test ways to support care and help people get connected with the right HIV specialists.
Loma Linda, CaliforniaAges 18 years+ - NCT05663502Recruiting
Donate blood and tissue samples for HIV-related cancer research
This study collects blood and tissue samples to help researchers learn more about cancers related to HIV/AIDS. You may be able to join if you’re 18+ and have HIV and a cancer diagnosis, or (if HIV-negative) a certain cancer that is closely linked to AIDS-related cancers.
La Jolla, CaliforniaAges 18 years+ - NCT01336855Recruiting
Provide blood for studies comparing HIV groups
This study collects blood to help researchers run multiple projects, including comparing people who are HIV-negative with people who have HIV. It may help advance knowledge that could improve future testing or treatments.
San Francisco, CaliforniaAges 18 years+ - NCT00187512Recruiting
Study of how HIV treatment changes outcomes over time
This is an observational study (not a new drug) that tracks how living with HIV can change over time in different treatment situations. It may help researchers understand long-term effects of the modern “protease inhibitor era” and improve future care.
San Francisco, CaliforniaAges 18 years+
HIV trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting hiv studies listed above.
- University of California, San Francisco · 3 studies
- San Francisco General Hospital · 2 studies
- Bridge HIV CRS
- CAL-PEP
- Chemidox Clinical Trials California
- Folio Clinical Research
- Kindful Restoration
- Loma Linda University Medical Center
What taking part in a hiv study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
HIV trials in other states
Common questions
- Are there hiv clinical trials in California?
- Yes. We're currently tracking 66 recruiting hiv studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a hiv study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a hiv trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New hiv studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.