Clinical trials · Alabama
HIV clinical trials in Alabama
We’re tracking 19 recruiting hiv studies with a site in Alabama — including Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Alabama
- NCT05384145Recruiting
Improve HIV testing and follow-up in Alabama clinics
This trial is testing a “whole-people” plan to help more people get HIV tested, get connected to care, and stay on treatment. It is mainly for healthcare and community staff in specific Alabama counties.
Birmingham, AlabamaAges 13 years+ - NCT05719441RecruitingPhase 2
Antibodies plus early HIV treatment to try for HIV remission
This study tests whether giving special HIV-fighting antibodies along with starting standard HIV medicine soon after infection can help you reach “HIV remission.” It may reduce or delay the return of detectable virus, but you must be willing to follow close monitoring and specific study steps.
Birmingham, AlabamaAges 18–70 - NCT06263426Recruiting
Kidney transplant from donors with HIV: impact on rejection and long-term results
This study tests whether kidney transplants from donors with HIV are safe and effective for people with HIV who need a new kidney. It looks at long-term outcomes like rejection and survival.
Birmingham, AlabamaAges 18 years+ - NCT06829238RecruitingPhase 4
Metformin to boost immune function in people with a history of drug use
This study tests whether metformin, a common diabetes drug, can help restore immune system balance in people who have used injection drugs in the past. It includes both people living with HIV and those who are HIV-negative.
Birmingham, AlabamaAges 18–64 - NCT07044297RecruitingPhase 3
A study of a new long-acting shot to prevent HIV
This study tests an investigational long-acting shot (MK-8527) to prevent HIV. It is for HIV-negative people who are at higher risk through anal sex without condoms, and who have not used other long-acting HIV prevention before.
Birmingham, AlabamaAges 16 years+ - NCT07473778Recruiting
Study of Lenacapavir for HIV Prevention
This trial tests a new medication, lenacapavir, to see how well it works for preventing HIV. It is for people who want or need PrEP (a medicine to prevent HIV) and are interested in learning about different options.
Birmingham, AlabamaAges 18 years+ - NCT07569029RecruitingPhase 1
HIV vaccine with treatment break to boost immune response
This Phase 1 trial tests two new HIV vaccines (DV700P-RNA and DV701B1.1-RNA) combined with a monitored break from HIV medications in people with well-controlled HIV. The goal is to see if this approach safely strengthens the immune system's ability to fight HIV.
Birmingham, AlabamaAges 18–60 - NCT07390955RecruitingPhase 1
Safety study of three anti-HIV antibodies in healthy adults
This study is testing three experimental antibodies (ePGT121v1-LS, PGDM1400LS, and VRC07-523LS) that may help prevent HIV. It’s looking at their safety and how long they stay in the body. Healthy volunteers without HIV can join.
Birmingham, AlabamaAges 18–55 - NCT07292584Recruiting
Digital toolkit to help women start PrEP
This trial tests a digital toolkit to help women start taking PrEP, a medication that prevents HIV. It looks at whether the toolkit makes it easier for women to take PrEP consistently.
Tuscaloosa, AlabamaAges 18 years+ - NCT07231640Recruiting
Improving PrEP care for clinic staff
This study looks at ways to improve PrEP (pre-exposure prophylaxis) care by helping clinic staff track and support patients better. It's for healthcare workers, managers, and data staff at certain PrEP clinics.
Birmingham, AlabamaAges 18 years+ - NCT05547048RecruitingPhase 4
Phone-based support to help prevent HIV in justice-involved women
This study tests an integrated phone-based health program (e-health) designed for women involved with the justice system who have opioid use disorder. It aims to help people who qualify for HIV prevention (PrEP) stay protected, especially by using simple, ongoing support through phone access.
Birmingham, AlabamaAges 18 years+ - NCT05965518Recruiting
High-intensity exercise for brain and blood-vessel health in HIV
This trial tests whether high-intensity exercise can improve blood-vessel health and brain function in adults with HIV who are not very active and have thinking/memory problems. If you qualify, you’ll be asked to safely complete exercise and other study assessments.
Birmingham, AlabamaAges 50 years+ - NCT06013579Recruiting
Exercise study for older adults with HIV
This study tests whether high-intensity exercise can help improve thinking and memory, and build lasting exercise habits, in older adults living with HIV who feel tired and are not very active.
Birmingham, AlabamaAges 50–80 - NCT06370481Recruiting
HIV and addiction training program for Alabama clinics
This study tests a program to help people living with HIV in Alabama who also struggle with opioid or stimulant use. It takes place at your HIV clinic and checks whether a new approach to addiction care can improve your health.
Birmingham, AlabamaAges 18 years+ - NCT06856174RecruitingPhase 4
Menopause Hormone Therapy for Women with HIV
This trial tests whether hormone therapy can help manage hot flashes and night sweats in women living with HIV who are going through menopause. It's designed to see if this treatment is safe and effective for this group.
Birmingham, AlabamaAges 40–60 - NCT07143968RecruitingPhase 2
Resmetirom for people with MASLD and HIV
This study tests if resmetirom can help people who have both HIV and a liver condition called MASLD (fat buildup in the liver not caused by alcohol). You may qualify if your liver has a certain amount of fat and stiffness, and your HIV is well controlled with stable medication.
Birmingham, AlabamaAges 18 years+ - NCT05723653Recruiting
Cell phone social support for people not in HIV care
This study tests a social support intervention delivered through a “support person” (a confidant) to help people stay engaged in HIV care and improve viral suppression. It may help by strengthening support outside of clinic visits and making care easier to follow.
Birmingham, AlabamaAges 18–49 - NCT07221123RecruitingPhase 2
Smell and memory training for brain health
This study tests whether smell exercises can improve memory and thinking in people who are worried about their brain health. If you are 40 or older and have mild memory concerns, you may be able to join.
Birmingham, AlabamaAges 40 years+ - NCT05463692Enrolling by invitation
Study of STI prevention and sexual health in Alabama women
This study follows women in Alabama to better understand sexual health and STI prevention over time. You may be able to join if you recently had an STI report and you’re currently negative for HIV, gonorrhea, and syphilis.
Birmingham, AlabamaAges 18–89
HIV trials by city in Alabama
Where these studies are running in Alabama
Institutions with a site for the recruiting hiv studies listed above.
- University of Alabama at Birmingham · 13 studies
- Alabama CRS · 2 studies
- Central Research Associates · 2 studies
- UAB 1917 Clinic · 2 studies
- Birmingham AIDS Outreach
- Five Horizons Health Services
- Thrive Alabama
- University of South Alabama Mitchell Cancer Institute
What taking part in a hiv study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
HIV trials in other states
Common questions
- Are there hiv clinical trials in Alabama?
- Yes. We're currently tracking 19 recruiting hiv studies with a site in Alabama, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a hiv study in Alabama?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Alabama to take part?
- Not necessarily. These studies have a site in Alabama, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a hiv trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New hiv studies open in Alabama regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.