HIV clinical trials

Online HIV Stigma Training for Nursing Students

This online study tests a training program to help nursing students in Iran reduce stigma toward people living with HIV. It is only open to 3rd- and 4th-year nursing students at Kerman Medical University.

HIV+ donor hearts for HIV+ recipients

This trial tests whether hearts from donors who had HIV can be safely transplanted into people with HIV who need a heart transplant. It may offer a new option for those on the waiting list.

Helping men with HIV reduce drinking and improve HIV prevention

This study tests whether helping men with HIV who also drink heavily can lower their alcohol use and improve how well HIV treatment works to prevent passing the virus to others. It's for men living in fishing communities in Uganda.

HIV testing access for young children in Uganda

This study makes it easier for children in Uganda to get tested for HIV. It helps find kids who haven't been tested recently so they can learn their status and get care if needed.

Testing HIV risk again each year for male couples

This study looks at whether repeating HIV testing once a year for male couples at higher risk helps results stay on track over time. It includes couples who previously took part in an earlier study and are willing to keep participating.

P3 Trial: Estimating the Impact of a Multilevel, Multicomponent Intervention to Increase Uptake of HIV Testing and Biomedical HIV Prevention

Testing B-OK Bottles for HIV Medication Understanding in South Africa

This study tests a special 'B-OK' bottle designed to help people understand their HIV medication better. If you live in Gauteng and can come to the study offices for one visit, you might help find better ways to support HIV treatment with simple tools.

HIV and meth prevention study for HIV-negative men

This study tests a smartphone program to help HIV-negative men who have sex with men reduce meth use and improve PrEP adherence. It explores whether combining support for both behaviors is more effective than addressing them separately.

Intensive early HIV treatment in newborns to aim for remission

This study gives very early, intensive HIV medicine to infants diagnosed with HIV and follows them closely to see if HIV can go into remission (stop being detectable without ongoing treatment). It may help families understand whether treating right after birth can change a child’s long-term HIV outlook.

Testing for HIV in opioid treatment programs

This project studies how to improve offering and completing HIV (and hepatitis C) tests in opioid treatment programs. It may help increase timely follow-up and linkage to care when results are positive.

Study of emotional health in gender care clients

This study looks at the thoughts, feelings, and social situations of people seeking gender-affirming care—like hormones or surgery—at a clinic in Thailand. It helps doctors better understand their needs.

Cash payments for pregnant women with HIV

This study provides cash payments to pregnant women with HIV who are living on a low income in Botswana. It aims to see if extra money can help improve health outcomes for both mother and baby.

Check whether home blood drops work for HIV monitoring

This study tests whether people with HIV can safely collect small blood samples at home using finger-pricks and devices (“dried blood spots”). It may help make HIV monitoring easier and more convenient while on certain HIV medicines.

Program to help HIV care and safety from partner violence

This study tests a program designed for Black women living with HIV who have had partner violence. It aims to help you stay engaged in HIV care and reduce intimate partner violence, while keeping you safe during the study.

Study tests standardized e-cigarette effects in people with HIV who smoke

This study looks at how a specific e-cigarette affects health in people who have HIV and smoke cigarettes regularly. You might be able to join if you meet smoking, HIV care, and safety requirements and are not planning to quit right away.

Test HIV medicines for people with new or long-term HIV

This Phase 3 study looks at antiretroviral treatment (HIV medicines) for adults with either recent (acute) or long-term (chronic) HIV. It’s designed to see how well and safely ongoing HIV treatment works, and it may help you get structured care and monitoring.

HIV Prevention Decision Tool for Young Adults

This study tests a simple online tool to help young people decide whether PrEP (a daily pill that prevents HIV) might be right for them. The tool uses information from an at-home HIV test and is designed to make PrEP information easier to understand.

Switching to a two-drug HIV regimen for transgender women

This trial tests if switching to a two-drug combination of dolutegravir and lamivudine is safe and effective for transgender women who already have undetectable HIV levels on a three-drug regimen. It aims to simplify treatment and reduce side effects.

Testing a drug to reduce hidden HIV early after treatment start

This trial tests whether adding venetoclax, a drug that helps infected cells die, at the start of HIV treatment can lower the amount of hidden virus that stays in the body. It may help reduce the HIV reservoir.

Metformin to boost immune function in people with a history of drug use

This study tests whether metformin, a common diabetes drug, can help restore immune system balance in people who have used injection drugs in the past. It includes both people living with HIV and those who are HIV-negative.

Housing help for people with HIV in Philadelphia

This study looks at how stable housing can improve the health of people with HIV. If you're in Philadelphia and eligible for a transitional housing program, you may be able to participate and help researchers understand the impact.

Legal help for people with HIV after incarceration

This study provides legal support to improve HIV care for people who have recently been released from jail or prison. It helps them stay in treatment and lower their viral load.

Testing an online HIV prevention program for people who inject drugs

This study tests whether an internet-based HIV prevention program works for people who use injection drugs. Researchers want to see if online tools can help reduce HIV risk and improve health outcomes.

HIV treatment decision support program

This study is testing a program to help people with HIV stick with their medication. It looks at how well doctors and patients work together to make treatment decisions and improve health outcomes.