Clinical trials
HIV clinical trials
Below are recruiting hiv clinical trials, each written for real people, not researchers. We’re tracking 583 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06967753RecruitingPhase 4
Switching to a two-drug HIV regimen for transgender women
This trial tests if switching to a two-drug combination of dolutegravir and lamivudine is safe and effective for transgender women who already have undetectable HIV levels on a three-drug regimen. It aims to simplify treatment and reduce side effects.
Buenos Aires, Buenos Aires F.D.Ages 18 years+ - NCT06934369Recruiting
Improving care for HIV and cancer in Zimbabwe
This study tests a program to help people living with HIV and a new cancer diagnosis stay engaged in their treatment. It is based at Parirenyatwa Hospital in Zimbabwe.
HarareAges 18 years+ - NCT06886971Recruiting
Strategies to help youth with HIV stay virally suppressed
This trial tests a strategy to help young people with HIV keep their virus levels low. It focuses on using a long-acting injectable medication combination (Cabotegravir and Rilpivirine) and requires communication with your HIV doctor.
Baltimore, MarylandAges 12–30 - NCT06842732Recruiting
Text messages to prevent wasting in HIV-affected children in Kenya
This trial tests if two-way text messages (SMS) can help caregivers recognize early signs of malnutrition (wasting) in children who have HIV or were exposed to HIV but are uninfected. The goal is to prevent wasting and keep children healthy.
Homa BayAges 6 months–2 years - NCT06829394Recruiting
Housing help for people with HIV in Philadelphia
This study looks at how stable housing can improve the health of people with HIV. If you're in Philadelphia and eligible for a transitional housing program, you may be able to participate and help researchers understand the impact.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06829238RecruitingPhase 4
Metformin to boost immune function in people with a history of drug use
This study tests whether metformin, a common diabetes drug, can help restore immune system balance in people who have used injection drugs in the past. It includes both people living with HIV and those who are HIV-negative.
Birmingham, AlabamaAges 18–64 - NCT06785376Recruiting
HIV testing and prevention program for Black men
This trial tests a program to help Black men in NYC who have sex with men access HIV testing and prevention pills. Your participation could help make HIV prevention easier to get for you and your community.
New York, New YorkAges 18–65 - NCT06741319Recruiting
Study of emotional health in gender care clients
This study looks at the thoughts, feelings, and social situations of people seeking gender-affirming care—like hormones or surgery—at a clinic in Thailand. It helps doctors better understand their needs.
Pathum Wan, BangkokAges 16 years+ - NCT06702722Recruiting
Therapy and HIV support for moms in Malawi
This study tests if combining problem-solving therapy with HIV care support can improve mental health and HIV outcomes for pregnant women living with HIV in Malawi who have elevated depressive symptoms.
LilongweAges 18 years+ - NCT06612554Recruiting
Zinc supplements for HIV patients with low CD4 counts
This trial tests whether taking zinc supplements helps HIV patients who have low CD4 cell counts even when their virus is well-controlled. If your zinc levels are normal but your immune cells are slow to recover, this might be for you.
BarcelonaAges 18 years+ - NCT06501781Recruiting
PUSH: Helping People with HIV and Substance Use
This study tests if a program that encourages positive activities (behavioral activation) can help people with HIV or on PrEP who also use substances improve their health. It focuses on those receiving long-acting injectable medications for HIV prevention or treatment.
Washington D.C., District of ColumbiaAges 18–88 - NCT06484335RecruitingPhase 1
HIV vaccine study with treatment pause for Thai adults
This study tests whether adding an experimental vaccine can help your immune system control HIV during a temporary break from your antiretroviral therapy (ART). If you have been on ART since shortly after infection with a suppressed viral load, this trial could help you understand if a 'functional cure' is possible.
Pathum Wan, BangkokAges 18–60 - NCT06483854Recruiting
HIV testing from traditional healers in rural South Africa
This trial compares HIV counseling and testing provided by traditional healers to the standard care approach. If you are over 18 and would like to receive an HIV test from a traditional healer, you may be able to join.
Agincourt, MPAges 18 years+ - NCT06171919Recruiting
Legal help for people with HIV after incarceration
This study provides legal support to improve HIV care for people who have recently been released from jail or prison. It helps them stay in treatment and lower their viral load.
Orlando, FloridaAges 18–100 - NCT06088277Recruiting
Texting to reduce HIV risk for dental patients
This study tests if daily text messages can help people lower their risk of getting HIV. You'll receive texts for a few months and complete surveys to see if the messages help.
Boston, MassachusettsAges 18 years+ - NCT05973825Recruiting
HIV blood study to study immune responses over many years
This study looks at how the immune system and HIV behave in people on long-term HIV treatment (ART), using blood samples that will be stored for future tests for up to 20 years. It may help researchers understand how well treatment is controlling HIV and improve future care.
Ghent, Oost-VlaanderenAges 18–80 - NCT05897099Recruiting
Telehealth harm-reduction for people at HIV risk
This study tests whether a telehealth program can reduce harm and lower HIV risk by helping with safer syringe use. It may help if you have recent syringe exchange use and are not currently on HIV prevention pills.
Miami, FloridaAges 18 years+ - NCT05488431RecruitingPhase 2
Bempedoic acid to lower cholesterol and inflammation in HIV
This Phase 2 trial studies whether bempedoic acid can lower cholesterol and inflammation in people with HIV who are already on effective HIV medications. It may help reduce signs of artery inflammation that can contribute to heart and stroke risk.
Los Angeles, CaliforniaAges 40 years+ - NCT05492565Enrolling by invitation
Follow-up study for people on HIV prevention pills
This study follows adults who are at high risk of getting HIV while they take HIV prevention pills (PrEP). It aims to learn how well PrEP fits real-life use in people at risk and who may need extra care.
Seville, AndalusiaAges 18 years+ - NCT05147519Recruiting
Observes HIV and other infections to learn who gets them
This is an observational study that follows people to better understand how HIV and other infections (like sexually transmitted infections) happen and change over time. It may help researchers improve prevention and care, but it is mainly for monitoring rather than testing a new treatment.
Kericho, Kericho CountyAges 14–55 - NCT04979728Recruiting
Check whether home blood drops work for HIV monitoring
This study tests whether people with HIV can safely collect small blood samples at home using finger-pricks and devices (“dried blood spots”). It may help make HIV monitoring easier and more convenient while on certain HIV medicines.
Aurora, ColoradoAges 18 years+ - NCT04563715Enrolling by invitation
Study on HIV prevention for at-risk Latino adults
This study looks at ways to prevent HIV in Latino adults who are at higher risk. It may help by testing HIV prevention approaches in specific local communities.
Indianapolis, IndianaAges 18 years+ - NCT03449706Recruiting
Tracking immune changes in early HIV
This study looks closely at how your immune system and HIV infection markers change right after a new HIV diagnosis. It may help doctors understand the earliest stages of HIV and improve how infections are measured and followed over time.
Ghent, Oost-VlaanderenAges 18–65 - NCT03135886Recruiting
Testing for HIV in opioid treatment programs
This project studies how to improve offering and completing HIV (and hepatitis C) tests in opioid treatment programs. It may help increase timely follow-up and linkage to care when results are positive.
New York, New YorkAges 18 years+
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Common questions
- Are there clinical trials for hiv?
- Yes. Clin2 currently lists 583 recruiting hiv studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hiv trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hiv trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.