Clinical trials
Hyaluronic Acid clinical trials
Below are recruiting hyaluronic acid clinical trials, each written for real people, not researchers. We’re tracking 69 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06447311Recruiting
Hyaluronic acid gel for gum tissue rebuilding
This study tests whether a hyaluronic acid gel can help rebuild gum tissue between teeth. It may be an option if you have gum recession in your front teeth and are in good oral health.
Mahbūbnagar, TelanganaAges 18 years+ - NCT06694532RecruitingPhase 1/Phase 2
Arthrocentesis with hyaluronic acid for TMJ disorders
This trial tests two types of hyaluronic acid (high vs low molecular weight) given during a jaw joint procedure (arthrocentesis) to see which better relieves pain and improves jaw function in people with TMJ disorders.
AsyutAges 18–100 - NCT06860659Enrolling by invitationPhase 4
Hyaluronate eye drops for moderate to severe dry eye
This trial tests whether 0.28% sodium hyaluronate eye drops can help people with moderate to severe dry eye feel better. It's for patients who have significant dry eye symptoms and signs on an eye exam.
Bangkok, BangkokAges 18 years+ - NCT06937645RecruitingPhase 2
Hyaluronic acid wash to improve pregnancy in IVF
This trial tests whether washing the uterus with hyaluronic acid before embryo transfer can improve pregnancy rates in women undergoing a fresh IVF cycle.
AL-Kadimya, Baghdad GovernorateAges 18–40 - NCT07594184Recruiting
Can hyaluronic acid injections help dry mouth?
This study tests whether injections of hyaluronic acid—a naturally occurring substance—can relieve chronic dry mouth (xerostomia). If it works, it could offer a new treatment option for people who have had dry mouth for at least a year.
Barcelona, BarcelonaAges 18 years+ - NCT07323342Recruiting
Hyaluronic acid plus fibrinogen for knee arthritis
This study tests whether a combination of two natural substances—hyaluronic acid (a joint lubricant) and fibrinogen (a blood protein that helps healing)—given as an injection into the knee, can safely reduce pain and improve function in people with knee osteoarthritis. It is for Vietnamese patients who have not recently used certain painkillers or had other knee treatments.
Ho Chi Minh CityAges 45–75 - NCT07099846Recruiting
Hyaluronic acid and polynucleotides for tooth socket preservation
This trial tests a gel made of hyaluronic acid and polynucleotides to help preserve the bone and gum after a tooth is pulled. It may help you keep a healthy foundation for a future dental implant.
ParmaAges 25 years+ - NCT07542808RecruitingPhase 2/Phase 3
Stem cell treatment vs. hyaluronic acid for knee arthritis
This study tests whether an injection of stem cells (special cells that can help repair tissue) works better than a standard hyaluronic acid injection for knee osteoarthritis pain. Both treatments are injected into the knee to reduce pain and improve function.
Abu DhabiAges 18 years+ - NCT07746206RecruitingEarly Phase 1
Insulin vs hyaluronic acid gel for advanced gum disease
This study compares two treatments applied directly to the gums to see which one better helps severe gum disease (periodontitis) heal. If you have advanced gum disease and haven't had treatment recently, you may be able to join.
CairoAges Any age - NCT07126912Recruiting
Alcarisa filler for mid-face volume restoration
This trial tests a new hyaluronic acid filler called Alcarisa to restore volume in the mid-face (cheek area). It may be a good option if you are looking for a non-surgical way to treat moderate to significant cheek volume loss.
Tehran, Tehran ProvinceAges 30–65 - NCT07102186RecruitingPhase 4
Adapalene plus hyaluronic acid gel for mild to moderate acne
This trial compares a gel containing adapalene (a retinoid) plus hyaluronic acid (a moisturizer) to adapalene gel alone for mild to moderate acne. It aims to see if adding hyaluronic acid helps reduce irritation and improve results.
Cairo, Cairo GovernorateAges Any age - NCT07683351Recruiting
Gel for healing after gum graft surgery
This study compares two gels, active oxygen gel and hyaluronic acid gel, to see which one helps the roof of the mouth heal better after a gum graft. It may help reduce discomfort and speed up recovery.
Ismailia, Ismailia GovernorateAges 18–60 - NCT07714811Recruiting
Hyaluronic acid vs PRP for chronic tendon pain
This study compares two treatments—hyaluronic acid (a natural lubricant) and platelet-rich plasma (PRP, made from your own blood)—for chronic tendon pain. You may be a good fit if you have had pain in your Achilles tendon or golfer's elbow for more than 3 months and are looking for a non-surgical option.
Lublin, Lublin VoivodeshipAges 18–65 - NCT07539194Recruiting
Hyaluronic acid injection for wear-and-tear knee cartilage tears
This trial tests a single injection of hyaluronic acid (a lubricating fluid) into the knee to relieve pain from degenerative meniscus tears—the kind caused by age and wear, not injury. The goal is to see if it safely reduces pain and improves how well your knee works.
Milan, MIAges 35–75 - NCT07081230Recruiting
Albumin vs hyaluronic acid with growth factors for gum disease
This trial tests whether adding albumin or hyaluronic acid (both natural substances) to a special gum treatment helps heal gum pockets better. It is for people with moderate to advanced gum disease.
Al Mansurah, MansouraAges 25–45 - NCT06522438Recruiting
Gel with Hyaluronic Acid for Gum Disease Treatment
This study tests whether a gel containing hyaluronic acid and octenidine can improve the results of standard deep cleaning for advanced gum disease. It may help reduce gum pocket depth and bleeding without the need for surgery.
LondonAges 18 years+ - NCT05085067Recruiting
Gel treatment to help prevent scar tissue after pregnancy tissue removal
This study tests whether an injected gel helps prevent scar tissue from forming again after a procedure to remove leftover pregnancy tissue inside the uterus. If you qualify, you may receive the gel as part of a randomized trial to see if it lowers the chance of re-adhesions (re-forming tissue sticking).
Beijing, Beijing MunicipalityAges 18–45 - NCT06309719Recruiting
Hyaluronic acid and polynucleotides for gum disease treatment
This trial tests if a gel made from hyaluronic acid and polynucleotides can help repair gum damage in people with advanced gum disease. You may be eligible if you have deep pockets between your teeth and gums that haven't healed after standard cleaning.
LondonAges 18 years+ - NCT07522684Recruiting
Gel treatment for deep gum bone loss around teeth
This trial tests a special gel made with growth-promoting compounds and animal-derived material to help repair deep bone loss in the gums around teeth. It may help restore bone that periodontitis (advanced gum disease) has damaged.
Ribeirão Preto, São PauloAges 18 years+ - NCT07305519Recruiting
Can supplements prevent early birth for short cervix?
This study tests if taking a combination of magnesium, a natural supplement (palmitoylethanolamide), hyaluronic acid, and vitamins B6 and D can help prevent preterm birth in women with a shorter-than-ideal cervix.
Rome, RMAges 18 years+ - NCT07204691Recruiting
Hyaluronic acid lip filler with lidocaine study
This study tests a new hyaluronic acid filler with lidocaine for making lips fuller. It is for healthy adults with thin lips who want a noticeable improvement.
MölndalAges 18 years+ - NCT06653985Recruiting
Hip injection plus physical therapy for mild hip problems
This trial tests a combination of a steroid and lubricant injection into the hip joint plus physical therapy to treat mild hip arthritis or related issues like a labral tear. It aims to see if this approach can reduce pain and improve function without surgery.
Hamilton, OntarioAges 40–60 - NCT07763990Recruiting
Injectable hyaluronic acid for facial volume and lines
This study tests a new injectable filler made of hyaluronic acid (a natural substance that adds volume) to improve the look of lips, smile lines, or cheeks. If you qualify, you'll receive the treatment and be monitored for safety and results.
Tel AvivAges 21 years+ - NCT07718347Recruiting
Growth-factor gel after laser for skin rejuvenation
This study tests a natural growth-factor solution applied after a laser treatment to improve skin's appearance. It may help you if you are a middle-aged adult with sun damage looking for enhanced healing and results from a laser procedure.
Sacramento, CaliforniaAges 40–70
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Common questions
- Are there clinical trials for hyaluronic acid?
- Yes. Clin2 currently lists 69 recruiting hyaluronic acid studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hyaluronic acid trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hyaluronic acid trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.