Intervention Study clinical trials

Environmental factors and infertility treatment outcomes study

This study follows people trying to have babies through fertility treatment to understand how environmental factors and lifestyle habits affect treatment success. By sharing your background and habits, you help researchers learn what may improve fertility outcomes.

Ultrasound test for abdominal injuries in children after blunt trauma

This study looks at how well an abdominal ultrasound test (FAST) works for children who come to the emergency department after a serious blunt injury to the belly or torso. The goal is to help doctors find dangerous internal bleeding or organ injury quickly and safely.

Safety study of an antibiotic for ABC infection

This study checks how safe sulbactam-durlobactam (a combination antibiotic) is in adults with a serious infection caused by ABC bacteria, especially looking for allergic reactions. If you are already getting this antibiotic as part of your care, you may be able to join.

Tislelizumab after surgery for early-stage lung cancer

This trial tests whether a drug called tislelizumab, given after surgery, can help prevent lung cancer from coming back. It is for people with stage I non-small cell lung cancer who have certain high-risk features and a protein called PD-L1 on their tumor cells.

Studying a new heart valve replacement system for aortic stenosis

This trial is testing a new heart valve system (Medtronic Evolut FX+) for people with severe aortic stenosis—a condition where the heart's main valve is narrowed. The study aims to see how well the valve works and improve your care journey.

Safety study of AZD4248 in healthy people and those with kidney disease and diabetes

This trial tests an experimental drug called AZD4248 to see if it's safe for healthy people and for people with chronic kidney disease and type 2 diabetes. It also checks if a home device can accurately measure kidney function.

Perinatal mental health support for expecting and new mothers

This trial tests a program that provides mental health support to pregnant women and new mothers through their usual healthcare visits. The goal is to see if offering this support as part of routine care can help prevent anxiety and depression.

How Germany's hospitals prepare for crises: The KAEPacity study

This study looks at hospital plans across Germany to see how well they are ready for disasters and emergencies. It examines their organizational structures, communication, and leadership training without any medical treatment involved.

Check, monitor, control hypertension study

This 24-month trial tests whether combining pharmacist counseling with community health worker support helps African Americans aged 55+ better control their high blood pressure. You will receive extra guidance to manage your blood pressure at home.

Personalized brain stimulation for irritable bowel syndrome

This study uses brain stimulation (TMS) customized for each person to treat IBS. It uses MRI scans to see how the brain responds, aiming to find better ways to predict who will benefit from this therapy.

Exercise training for children with cerebral palsy

This study looks at whether a supervised exercise program can improve health and well-being in children with mild cerebral palsy. It compares them with typically developing children who are not already in a regular exercise routine.

Exploring HER2 testing in high-grade ovarian cancer

This study looks at how to best detect the HER2 protein in high-grade serous ovarian cancer. The goal is to improve treatment choices for people with this type of cancer.

This Study Examines Whether Personality Traits Influence the Frequency or Severity of Ocular Adverse Effects Reported by Patients Using Glaucoma Medications. The Findings May Identify Patients at Greater Risk of Intolerance and Support More Personalized Treatment and Counselling.

Study of gut bacteria in people with serious long-term illness

This study looks at the types of gut bacteria in people living in certain parts of China who have serious long-term (chronic) illnesses. The goal is to better understand how gut bacteria differ and may help doctors in the future tailor care.

Rare GSD Natural History Study

This study follows people with rare types of glycogen storage disease (GSD) over time to learn more about how the disease progresses. It does not test a new treatment but will collect information to help future research.

Better Breathing After Lung Cancer Treatment

This study looks at breathing exercises for people who have finished treatment for early-stage lung cancer. You'll be asked to give a blood sample at home and do breathing training to see if it helps your recovery.

Study on HRD test and PARP inhibitor for ovarian cancer

This trial looks at a genetic test called HRD to see if it can predict how well PARP inhibitors (a type of targeted therapy) work for ovarian cancer patients. It is for women who have been treated with platinum chemotherapy and are now on PARP inhibitor maintenance therapy.

Managing Fear and Worry in Advanced Cancer

This study tests a new approach to help people with advanced cancer who feel significant fear about their cancer getting worse or coming back. The program uses writing and therapeutic techniques to help reduce this fear and related stress.

Reducing bloodstream infections from ICU catheters

This study tests a new method to prevent infections from central lines (special IVs placed in large veins) in intensive care units. If you have a central line in place for more than 24 hours, this research may help improve your safety by finding better ways to avoid catheter-related bloodstream infections.

European study on multiple and mixed valve disease

This study looks at people with multiple or mixed heart valve disease (moderate or severe) using echocardiography. It aims to learn more about how these conditions affect patients and help guide future care.

Using an interactive projector to reduce anxiety in children during anesthesia

This trial tests whether an interactive projector can help distract children aged 2 to 6 while they are going under anesthesia for surgery, with the goal of lowering their anxiety. It compares the projector to standard care to see if it makes the experience less stressful for the child and family.

Hospital study following people with plasma cell disorders

This is a hospital-based study that follows people with plasma cell disorders to better understand these conditions. It mainly gathers information from patients who are confirmed to have one of several related diseases.