Clinical trials
Irritability clinical trials
Below are recruiting irritability clinical trials, each written for real people, not researchers. We’re tracking 147 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05815602RecruitingPhase 3
Ebastine vs mebeverine for non-constipation IBS
This Phase 3 study compares ebastine and mebeverine to see which works better for people with IBS that is not constipation-predominant. If you have IBS symptoms without an underlying intestinal disease, you may be offered one of these medicines and monitored for symptom improvement.
Antwerp, AntwerpenAges 18–65 - NCT05930886Recruiting
Focus groups with diverse parents about child mental health
This study brings together Black and Hispanic/Latino parents or caregivers to discuss what it’s like to seek help for a child’s attention or emotional challenges. Your feedback helps researchers test whether a future treatment and support program would be practical and acceptable for families.
Portland, OregonAges 18–80 - NCT05972291Recruiting
Study gut changes in Gulf War illness with chronic stomach symptoms
This study looks at what’s driving Gulf War illness, focusing on gut symptoms like belly pain, diarrhea, and bloating. It may help researchers test approaches aimed at gut barrier function in eligible veterans.
Memphis, TennesseeAges 18–65 - NCT06073886RecruitingPhase 2
Better brain stimulation for long-lasting concussion symptoms
This trial tests whether personalized brain stimulation can help people who have ongoing symptoms more than 20 on a standard concussion scale, such as headaches, dizziness, or trouble concentrating, after a mild head injury in the past year.
Westwood, Los Angeles, CaliforniaAges 18–65 - NCT06133231Recruiting
ADHD research with Black and Hispanic families
This study tests if a new approach to ADHD research works well with diverse families. It involves taking supplements and collecting samples at home to see how the body responds.
Portland, OregonAges 6–17 - NCT06211062RecruitingPhase 2
Probiotics for chronic fatigue syndrome with IBS
This study tests whether a specific mix of probiotics can help people with chronic fatigue syndrome (ME/CFS) who also have irritable bowel syndrome (IBS). It's a small trial to see if improving gut health can ease symptoms.
Fort Lauderdale, FloridaAges 45–70 - NCT06215222Recruiting
Studying gut bacteria in IBS and digestive issues
This study uses a tiny capsule to collect samples from your small intestine to learn about gut bacteria in people with IBS or other functional gut disorders. It could help researchers understand what causes digestive symptoms.
Redwood City, CaliforniaAges 18–70 - NCT06268964RecruitingPhase 1/Phase 2
Trimebutine vs probiotics for kids with belly pain
This study compares two treatments—trimebutine and probiotics—to see which works better for children with recurring stomach pain that has no clear medical cause. It aims to find a safe and effective option for kids aged 4 to 18.
ColimaAges 4–18 - NCT06288672Recruiting
Skin patch test for food allergies in IBS
This study tests whether a skin patch can help identify food allergies in people with irritable bowel syndrome (IBS) whose symptoms are not well controlled. It involves avoiding certain foods and using patches on your back to see if you react.
North Wales, PennsylvaniaAges 18 years+ - NCT06369753Recruiting
Study on visible belly swelling after meals
This study looks at people whose belly visibly swells after eating. The goal is to understand this condition and track symptoms over time.
Los Angeles, CaliforniaAges 18–80 - NCT06414967Recruiting
Music therapy for irritability in Huntington's disease
This study tests if music therapy can help reduce irritability and impulsivity in people with Huntington's disease. You'll participate in music sessions to see if it improves your mood and behavior.
PoitiersAges 18 years+ - NCT06495606Recruiting
How stomach acid affects your voice
This study looks at how stomach acid backing up into the throat can change the voice. It may help find typical voice differences in people with acid reflux.
BernAges 18 years+ - NCT06551961Recruiting
How two fibers affect your gut health
This study tests how two types of fiber (inulin and methylcellulose) affect your gut when eaten regularly. You'll eat provided meals and have your breath tested to see how your gut breaks down the fiber.
Nottingham, NottinghamshireAges 18–65 - NCT06596733Recruiting
Testing a new eye ointment for dry eyes (Vit-A-Vision)
This trial tests a medical device eye ointment called Vit-A-Vision for people with dry eye disease. It aims to see if the ointment can improve symptoms and tear film stability over about a month.
CologneAges 18 years+ - NCT06639984RecruitingPhase 2
Psyllium for kids with IBS
This study tests if psyllium, a fiber supplement, helps reduce belly pain and other symptoms in children with irritable bowel syndrome (IBS). It may be an option if standard treatments haven't worked well.
Durham, North CarolinaAges 12–17 - NCT06665867Recruiting
Video Follow-Up for Kids With Stomach Pain
This trial tests whether video consultations (video calls) are a good option for follow-up appointments in children with functional abdominal pain disorders. It aims to make check-ups easier for families.
AmsterdamAges 4–17 - NCT06684470RecruitingEarly Phase 1
Combining a low-FODMAP diet with medication for IBS-D
This trial tests if a special diet (low-FODMAP) combined with a medication (mirtazapine) can improve IBS with diarrhea symptoms. It is for adults who have not tried these treatments before.
Jacksonville, FloridaAges 18–70 - NCT06721624Recruiting
Natural approaches for IBS: a research study
This study observes how naturopathic treatments help people with Irritable Bowel Syndrome (IBS) or IBS-like symptoms. It aims to understand what works in real-world care.
Portland, OregonAges 18 years+ - NCT06727422RecruitingPhase 2
Rifaximin plus NAC for IBS with diarrhea
This trial tests whether a combination of two medications—rifaximin (a gut antibiotic) and NAC (a supplement that helps break down mucus)—can reduce belly pain and diarrhea in people with IBS whose symptoms are not well controlled. It may be an option if other treatments haven't worked well enough.
Los Angeles, CaliforniaAges 18 years+ - NCT06749613Recruiting
Digestive enzymes for IBS after diet response
This trial tests whether a digestive enzyme supplement can help people with irritable bowel syndrome (IBS) whose symptoms returned after they previously improved on a special low-FODMAP Mediterranean diet.
Chaïdári, AthensAges 18–65 - NCT06805903Recruiting
Validating a survey on transanal irrigation adherence
This study tests a new survey to better understand how well people are following their transanal irrigation treatment. If you use this treatment for bowel issues, the researchers want to see if the survey accurately measures your routine.
ParisAges 18 years+ - NCT06814314Recruiting
Kids' metabolism and antipsychotic medication study
This study looks at how antipsychotic medicines affect metabolism in children ages 5-17. It compares those with and without metabolic issues, and a group not taking these medicines, to understand how their bodies process energy.
Bosisio Parini, LCAges 5–17 - NCT06847360Recruiting
Home-based ear stimulation for IBS pain
This trial tests a gentle, non-invasive ear stimulation device (taVNS) used at home to reduce pain from Irritable Bowel Syndrome (IBS). It might help if you have moderate pain most days.
New Haven, ConnecticutAges 18–29 - NCT06865430Recruiting
Managing urinary symptoms after HoLEP surgery
This trial tests if alpha-blocker medication can reduce painful or frequent urination after a prostate surgery called HoLEP. It may help you recover more comfortably.
AnkaraAges 40–85
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Common questions
- Are there clinical trials for irritability?
- Yes. Clin2 currently lists 147 recruiting irritability studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a irritability trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a irritability trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.