Clinical trials
Joint Diseases clinical trials
Below are recruiting joint diseases clinical trials, each written for real people, not researchers. We’re tracking 54 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05871216Recruiting
Study of joint instability in people with loose joints
This trial is testing how to assess and manage joint instability in people who have unusually loose (hypermobile) joints. If you have moderate to severe loose joints, you may be able to join after screening checks like movement tests and health history.
BolognaAges 18–60 - NCT06451588RecruitingPhase 2
Fecal transplant for inflammatory back pain
This study tests whether a fecal microbiota transplant (a procedure that transfers healthy bacteria into your gut) can reduce inflammation and improve symptoms in people with inflammatory back pain (axial spondyloarthritis). It may help if your current treatments are not working well enough.
TromsøAges 18–65 - NCT05440240RecruitingPhase 4
Needling and possibly steroid shot for Dupuytren’s hand tightness
This trial tests a minimally invasive procedure that uses a needle to release tight tissue in the hand, and may include a steroid injection. It aims to improve hand finger straightening for people with Dupuytren’s contracture.
SilkeborgAges 45–99 - NCT04536103Recruiting
Accelerated MRI scans after ACL knee injury surgery
This trial tests a faster MRI scan method to measure healing in the knee after an ACL (anterior cruciate ligament) tear and reconstruction. It may help researchers compare scan quality while participants go through standard rehab.
Cleveland, OhioAges 18–50 - NCT06074744Recruiting
Nerve blocks for knee replacement pain relief
This study compares two types of nerve blocks (subsartorial and femoral) to see which provides better pain control after knee replacement surgery. Both are injections that numb the nerves around your knee to help with recovery.
LucerneAges 18 years+ - NCT04580225Recruiting
Tested partial wrist fusion with or without bone removal
This study compares two surgical options for certain types of advanced wrist arthritis—one with partial wrist fusion alone, and one with partial wrist fusion plus removal of a small wrist bone. It may help find which approach works better for pain and function after surgery.
Calgary, AlbertaAges 18–75 - NCT07536529Recruiting
Oxidative Stress in Autoimmune Joint Diseases
This study looks at a type of cellular damage called oxidative stress in people with autoimmune joint diseases like rheumatoid arthritis, psoriatic arthritis, or ankylosing spondylitis. Researchers want to understand how this damage relates to your disease and may help develop better treatments.
Larissa, ThessalyAges 18 years+ - NCT07147530RecruitingPhase 4
Powered exercise device for walking in hip disease
This study tests a new powered exercise device designed to help people with hip problems walk better. It may be a good option if you have hip osteoarthritis or avascular necrosis and can do some standing and walking with support.
Yongin-si, Gyeonggi-do, South KoreaAges 19 years+ - NCT06312943Recruiting
Biomarker study for inflammatory and non-inflammatory joint diseases
This study collects fluid from your joints (synovial fluid) or tissue from joint replacement surgery to look for biomarkers (biological clues) that could help doctors better diagnose bone and joint diseases.
Paris, IDFAges 18 years+ - NCT06883669Recruiting
AI for wrist and hand joint ultrasound
This study is testing if an artificial intelligence program can help doctors take clearer images of the wrist and hand using ultrasound. It is for healthy volunteers to help build the AI system, and for experienced sonographers to test how well it works.
Chengdu, SichuanAges 18–100 - NCT02418442Recruiting
Kid rheumatic disease registry study for follow-up care
This is an observational study that follows children and teens with rheumatic (joint/inflammatory) diseases to better understand how they develop and are cared for over time. You may help by letting the study contact your family in the future and by completing study tasks as needed.
Birmingham, AlabamaAges Up to 21 years - NCT06025149Recruiting
Study of a New Biological Heart Valve 'UniLine'
This study tests a new biological heart valve called 'UniLine' for people who need to replace their mitral valve (the valve between the left heart chambers) or aortic valve (the main valve sending blood to the body) for the first time. If you qualify, you would have planned surgery (not an emergency) and need to be free of certain other serious health conditions.
Kemerovo, Kemerovo OblastAges 18–80 - NCT07748858Recruiting
Heart care support for older African American patients
This study aims to improve care for older African American patients with heart conditions and other health problems. It tests ways to provide more patient-centered support.
Birmingham, AlabamaAges 50–99 - NCT05227924Recruiting
Testing safety and performance of a hip implant device type
This study checks how safe and well a specific brand of hip implant (SYMBOL range) works in people getting a total hip replacement. It may help by confirming the device performs as expected for primary or revision surgeries.
BeaumontAges 18 years+ - NCT01581294Recruiting
Norwegian arthritis drug registry for new biologic or kinase treatment
This study is a real-world registry that follows adults with inflammatory arthritis when they start a new targeted medicine. It helps researchers understand how these drugs work in everyday care.
Drammen, BuskerudAges 18 years+ - NCT02653079Recruiting
Blood testing and low-dose radiation for painful joint conditions
This study collects blood samples and treats certain painful joint/soft-tissue problems with low-dose local radiation therapy. It aims to understand disease features and how patients may respond to this treatment.
Erlangen, BavariaAges 18 years+ - NCT03048201Recruiting
Total Knee Replacement Registry Study for a Specific Knee Implant
This study tracks outcomes for people getting a total knee replacement using a specific knee implant system. It may help doctors understand which patients do best and how the implant performs over time.
Rancho Mirage, CaliforniaAges 22 years+ - NCT06142669Recruiting
Knee revision study using EVOLUTION parts
This study checks how well a specific knee replacement system works in people who need a revision knee surgery (replacing a previous implant). If you have had or will have this surgery with the EVOLUTION parts, researchers will follow you for 10 years to see how the implant performs.
Milan, Piazza C. Ferrari 1 20122 MilanAges 21 years+ - NCT07651735Recruiting
Safety and Recovery Study of Tipmed Hip Replacement
This study tracks how well people recover after hip replacement surgery using the Tipmed hip implant system. Researchers will monitor your healing and implant performance over time to ensure the device works safely and effectively.
BalıkesirAges 18 years+ - NCT07651215Enrolling by invitation
Short-Stem Shoulder Replacement Surgery Outcomes Study
This study looks at how well a newer type of shoulder replacement surgery works. Researchers are checking X-rays and patient function for people who had this specific short-stem surgery at least 2 years ago.
LinzAges 18 years+ - NCT06713902Recruiting
Extracellular vesicles in fibrin gel for cartilage repair
This trial studies whether adding special healing particles (extracellular vesicles) to a natural gel can help repair cartilage in people with knee or hip osteoarthritis. It looks at patients already scheduled for surgery or regenerative treatments like PRP.
Milan, MIAges 18 years+ - NCT07533188Recruiting
Robotic Knee Replacement Surgery Alignment Techniques Study
This study compares two different ways surgeons can align and position a robotic knee replacement to see which gives better results. You'll be randomly assigned to one approach and tracked over time to measure pain, function, and satisfaction.
SingaporeAges 18 years+ - NCT07199738Recruiting
Knee replacement study with a new implant option
This study tests a specific knee implant insert (LEGION Medial Stabilized) in people who need a total knee replacement due to arthritis or similar joint disease. It aims to see if the device is safe and works well over time.
Newton, MassachusettsAges 18–80 - NCT07125833Recruiting
Cold therapy for shoulder replacement pain
This trial tests if freezing a nerve near the shoulder before surgery can reduce pain after a reverse total shoulder replacement. It may help you recover with less discomfort.
Rockwall, TexasAges 30–85
Hear when a new Joint Diseases trial opens
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Common questions
- Are there clinical trials for joint diseases?
- Yes. Clin2 currently lists 54 recruiting joint diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a joint diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a joint diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.