Clinical trials
Joint Diseases clinical trials
Below are recruiting joint diseases clinical trials, each written for real people, not researchers. We’re tracking 55 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06108934Recruiting
Study of the Insignia Hip Stem for First Hip Replacement
This study tests a new cementless hip stem (Insignia) for people having their first total hip replacement. It aims to see how long the implant lasts and how well your hip works after surgery.
Subiaco, Western AustraliaAges 18 years+ - NCT06955481Recruiting
Navigated knee replacement study for better outcomes
This study tests a computer-guided system for total knee replacement. It aims to see if using the OrthoPilot® navigation system helps improve surgical precision and long-term results.
ŠumperkAges 18–80 - NCT06920459Recruiting
Zimmer Biomet Shoulder Replacement Study
This study is testing a shoulder replacement system made by Zimmer Biomet to see how well it works for people with severe shoulder problems, like arthritis or fractures. If you qualify, you would receive the implant and be asked to come back for regular checkups to track your recovery.
PforzheimAges 20 years+ - NCT06718569Recruiting
Pain in Inflammatory Joint Diseases
This study looks at pain in people with inflammatory joint diseases. It aims to understand how pain changes when you start or switch to a newer type of arthritis medication.
OsloAges 18 years+ - NCT06477393Enrolling by invitation
Mud and mineral water baths for hand and foot osteoarthritis
This study tests whether natural mud and mineral water baths can help reduce pain and improve function in people with osteoarthritis of the hands or feet. If you have hand or foot pain from osteoarthritis and are looking for non-drug treatment options, this may be a good fit.
BirštonasAges 18 years+ - NCT06395883Recruiting
Steroids and Your Bones in Joint Disease
This study looks at how steroids affect bone health in people with inflammatory joint diseases like rheumatoid arthritis. Researchers will track markers in your blood to see if short-term steroid use impacts your bones.
DrammenAges 25–90 - NCT05980442Recruiting
Navigation vs robotic-arm assisted knee replacement
This study compares two different high-tech tools used during total knee replacement surgery: one that uses a navigation system (OrthoPilot) and one that uses a robotic arm (MAKO). The goal is to see if one method leads to better results. If you're having a total knee replacement, this trial could help your surgeon choose the best approach.
Ulm, Baden-WurttembergAges 18–90 - NCT05548972Enrolling by invitation
Follow-up study of a hip replacement to improve implant wear
This study checks how well a specific hip replacement bearing surface (called dual mobility with Vivacit-E or Longevity) performs over time in real-world patients. It may help people by tracking long-term safety and performance to guide better hip replacement choices.
Little Rock, ArkansasAges 18–80 - NCT05357378Recruiting
Hip replacement study using a reverse hip implant
This trial looks at how safe and well a specific “reverse” hip implant works in people who need their first total hip replacement. It may help by improving pain and hip function, while closely tracking safety during and after surgery.
Miami, FloridaAges 50–75 - NCT04816773Enrolling by invitation
Long-term follow-up for specific knee replacement parts
This study follows people for up to 10 years after a knee replacement done with specific manufacturer parts. It helps the company and doctors understand how well these knee implants work and whether they cause any long-term problems.
Fremont, CaliforniaAges 21 years+ - NCT04147559Enrolling by invitation
Long-term follow-up for a specific hip replacement stem
This study checks how well a particular hip replacement stem (the PROFEMUR Preserve Classic Femoral Stem) and matching parts keep working over many years. You may be invited if you had that exact hip replacement combination and can return for long-term checkups.
Scottsdale, ArizonaAges 21 years+ - NCT04064008Enrolling by invitation
Long-term follow-up for a specific hip revision stem
This study follows people who had a hip replacement redone (revision) because of bone healing problems or hardware removal, using a specific revision femoral stem. It checks how the stem does over time and follows up for up to 10 years after surgery.
OtwockAges Any age - NCT03576573Enrolling by invitation
Follow-up study for specific hip replacement components
This study checks outcomes after a specific type of hip surgery using specific brand parts. You may help by sharing follow-up visit information so the sponsor can confirm the components work as expected in everyday patients.
BuxtehudeAges 21 years+ - NCT07595094Recruiting
Blood Age Test for Predicting Health and Disease Risk
This study uses a special blood test to calculate your 'biological age' and predict your risk for serious illness, death, and how long you'll live healthy. Researchers want to understand if this test can help doctors catch health problems early.
Nanchang, JiangxiAges 35 years+ - NCT07830836Enrolling by invitation
Physiotherapy and osteopathy for recent neck, back, or jaw pain
This study tests whether physiotherapy and osteopathic treatment can help relieve recent (acute) pain in the neck, lower back, or jaw joint. It aims to understand if these hands-on therapies reduce pain and improve jaw function.
Gorzów Wielkopolski, Lubusz VoivodeshipAges 20–40 - NCT04814082Recruiting
Compare two knee implant types for walking and function
This study compares two designs of knee replacement implants to see how they affect walking, function, and outcomes after surgery. You may be randomly assigned to one of the implant types used for your specific, approved knee replacement.
Baltimore, MarylandAges 18–75 - NCT07790328Recruiting
Long-term safety of the IntraSPINE implant for low back pain
This study checks how safe and effective the IntraSPINE implant is over time for people with low back pain from degenerative discs. The implant is placed in your spine to support it, and this trial helps see if it continues working well for years.
SaranAges 18 years+ - NCT06320899Recruiting
Comparing different rods for lower back spine surgery
This study tests two types of rods (mid/high-flex vs low-flex) used during back surgery for people with degenerative spine problems in the lower back. The goal is to see which type helps reduce pain and improve movement better.
AarbergAges 18–99 - NCT06370312Recruiting
Biomarkers for thumb osteoarthritis surgery
This study looks at joint fluid and tissue samples from people with thumb base osteoarthritis who are already scheduled for a surgery called trapeziectomy. The goal is to find markers that might help better understand the disease and improve treatment.
Malmö, Skåne CountyAges 25 years+ - NCT05670301Recruiting
Blood test study to profile inflammation biomarkers in diseases
This study measures blood “biomarkers” (signals in blood) to better understand inflammatory diseases, including autoimmune and autoinflammatory conditions. You may be asked to give blood samples now and possibly extra samples if needed for testing.
AntwerpAges Any age - NCT06107400RecruitingEarly Phase 1
RM-004 cell therapy for Hemoglobin H-Constant Spring disease
This early-phase trial tests a new cell therapy called RM-004 for people with Hemoglobin H-Constant Spring disease, a form of alpha thalassemia that requires regular blood transfusions. The goal is to see if the treatment is safe and can reduce or eliminate the need for transfusions.
Nanning, GuangxiAges 12–35 - NCT06776965Recruiting
Ultra-processed foods and rheumatic disease study
This study explores how eating ultra-processed foods affects people with chronic rheumatic diseases like rheumatoid arthritis, spondyloarthritis, or osteoarthritis. It aims to understand if diet plays a role in symptom management.
LyonAges 18 years+ - NCT04297592Enrolling by invitationPhase 4
Antibiotics to prevent infection after hip or knee replacement
This trial studies whether giving antibiotics before and/or after surgery can lower the chance of a serious joint infection after elective hip or knee replacement. It’s aimed at people at higher risk for infection.
Iowa City, IowaAges 18–99 - NCT04375280Recruiting
Study of mobility problems in people with long-term illnesses
This study observes how people with chronic health conditions affect their ability to move and do everyday activities. It may help researchers better understand mobility limits and what factors influence them.
Clermont-FerrandAges 18–90
Hear when a new Joint Diseases trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for joint diseases?
- Yes. Clin2 currently lists 55 recruiting joint diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a joint diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a joint diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.