Clinical trials
Light clinical trials
Below are recruiting light clinical trials, each written for real people, not researchers. We’re tracking 277 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07266116RecruitingPhase 1/Phase 2
TQB2934 injection for light chain amyloidosis
This trial tests a new injectable drug called TQB2934 for people with systemic light chain amyloidosis. It aims to see if the drug is safe and effective for those whose disease has come back or gotten worse after previous treatment.
Beijing, Beijing MunicipalityAges 18–80 - NCT07298382Recruiting
Beem's blue light therapy for skin health
This trial tests if a blue light therapy device can improve your skin health. It is a simple, at-home study for people who want to see how their skin responds to light treatment.
New York, New YorkAges Any age - NCT06803082Recruiting
How systemic light chain amyloidosis affects the eyes
This study looks at how systemic light chain amyloidosis, a condition where abnormal proteins build up in organs, may affect your eyes. By comparing eye exams of people with and without the disease, researchers hope to learn more about eye-related changes so they can improve care.
Guangzhou, GuangdongAges 18–80 - NCT07747662Enrolling by invitation
Eye imaging study for early geographic atrophy
This study uses special eye imaging to look closely at areas of damage in the back of the eye (geographic atrophy) caused by age-related macular degeneration. It will help doctors understand early-stage disease better and may guide future treatments.
Madison, WisconsinAges 50 years+ - NCT07744711Enrolling by invitation
Testing a light therapy app on an iPad
This study tests an iPad app that provides light therapy, which may help with conditions like seasonal depression or sleep problems. You will use the app for a period of time, and you may also choose to provide blood samples for a biomarker sub-study.
New York, New YorkAges 18 years+ - NCT07323121Recruiting
Flickering light therapy for sleep problems in Parkinson's
This study tests whether a special flickering light (40 Hz) can help improve sleep in people with Parkinson's disease. Participants will be exposed to the light at home, and researchers will track changes in sleep quality.
Nanjing, JiangsuAges 50–75 - NCT03578003Recruiting
Bright morning light to improve sleep in veterans
This study tests whether using bright morning light can improve sleep quality in veterans. You may be able to join if you’re not already using a light box and you don’t have certain eye or mood conditions.
Portand, OregonAges 18 years+ - NCT03811964Recruiting
Test how light affects your sleep, mood, nerves, and vision
This study uses a light-based test (the “photomotor reflex”) to see how non-visual effects of light may affect sleep-wake timing, brain function, mental health, and eyesight. You may be assigned to a group based on your condition, or you may be in the healthy control group.
StrasbourgAges 18 years+ - NCT03921931Recruiting
Test retinal responses to light in healthy eyes or eye disease
This is a small pilot study that measures how parts of the retina change before and after light stimulation. It may help researchers understand eye function in people with normal vision or specific eye conditions like glaucoma or dry age-related macular degeneration (AMD).
Vienna, State of ViennaAges 18 years+ - NCT04578249Recruiting
Blocking blue light at night after heart surgery
This trial tests whether reducing blue light at night after certain planned heart surgeries helps protect mood, thinking, and recovery. If you have no history of major mental health problems or organ problems, you may be able to join the study.
Morgantown, West VirginiaAges 45–75 - NCT05829044Recruiting
How light exposure affects sleep and body clock by sex and age
This study looks at how non-visual light (light that isn’t just for seeing) affects your sleep timing and circadian rhythms, and whether the effects differ by sex and age. It may help researchers design better light-based or sleep-support strategies in the future.
Boston, MassachusettsAges 18–85 - NCT05072691Recruiting
Tests spinal fluid proteins to predict multiple sclerosis outlook
This study checks specific proteins in spinal fluid to see whether they can predict how multiple sclerosis (or related symptoms like optic neuritis) may go over time. It may help doctors better estimate prognosis using results from tests you may already be having.
BrusselsAges 18 years+ - NCT05177055Recruiting
Sleep program for delayed sleep timing with mental health symptoms
This study offers a sleep-focused program to people whose sleep schedule is significantly shifted later than desired (delayed sleep phase disorder) along with moderate to severe mental health symptoms. It aims to see if treatment for the sleep problem can help in people already getting psychiatric care.
Bergen, TertnesAges 18–80 - NCT05247125RecruitingPhase 4
Testing light or melatonin to help brain recovery after stroke
This study looks at whether changing your sleep timing using light therapy or melatonin can improve “brain rewiring” after an ischemic stroke. It mainly focuses on people who arrive very soon after stroke symptoms and who also meet specific safety and sleep/medication requirements.
Saint PetersburgAges 18–80 - NCT05423275Recruiting
Light treatment to help you stop antidepressants safely
This study tests whether a “light and ion” treatment can help people with major depression (MDD) who are doing well on antidepressants safely reduce or stop them. You must be in remission and be willing to discontinue for reasons like side effects or personal preference.
Vancouver, British ColumbiaAges 19–65 - NCT05519878Recruiting
Light plus job therapy for fatigue in genitourinary cancer
This trial tests whether light therapy and an occupational therapy fatigue program can reduce fatigue in people with certain urinary-system cancers who still have mild fatigue during treatment. It may help you feel more energized and manage day-to-day activity while cancer treatment is ongoing.
Duarte, CaliforniaAges 18 years+ - NCT05579392Recruiting
Bright light therapy for gut inflammation in Crohn’s or colitis
This trial studies whether daily bright light can improve gut barrier “leakiness” and reduce inflammation in adults with Crohn’s disease or ulcerative colitis. It compares bright light versus dim light in a crossover design, meaning you may receive both.
Chicago, IllinoisAges 18 years+ - NCT05606237Recruiting
Red-light sessions to slow worsening nearsightedness
This study tests whether repeated low-level red-light therapy can slow how fast nearsightedness (myopia) gets worse in children. It may help protect future eyesight, but your child must meet specific vision and health requirements and follow the study plan.
San Francisco, CaliforniaAges 8–13 - NCT05652335RecruitingPhase 1
JNJ-79635322 for hard-to-treat myeloma or amyloidosis
This Phase 1 study tests how safe and how well JNJ-79635322 works in people with multiple myeloma that has come back or is resistant to treatment, or AL amyloidosis that has already been treated. It may help by targeting cancer cells and abnormal proteins driving these diseases.
Duarte, CaliforniaAges 18 years+ - NCT05737732Recruiting
Testing ambient light for multiple myeloma patients
This study looks at whether using a special kind of everyday light (called ambient light) can help people with multiple myeloma as they prepare for their first stem cell transplant. It may be aiming to improve comfort or recovery by affecting sleep and the body’s natural signals from light.
New York, New YorkAges 21 years+ - NCT05775328Recruiting
Laser-like light treatment for excess hair in PCOS and gender dysphoria
This trial tests “intense pulsed light” (a light-based treatment) to reduce unwanted facial or body hair. It may help people who have excess hair due to PCOS and who have been evaluated for gender dysphoria, if it’s safe for their skin and hair type.
Umeå, Västerbotten CountyAges 18 years+ - NCT05808179Recruiting
Adjusting teens’ sleep timing at home
This study tries to move your teen’s bedtime earlier to see if shifting sleep timing is helpful. If your teen can follow the schedule and sleep mostly in their bedroom, they may be able to join.
Stanford, CaliforniaAges 14–18 - NCT05832723Recruiting
Red light eye therapy for children with mild focusing error
This study tests whether low-intensity red light at 650 nm can help children and teens with mild problems focusing their eyes. It is designed to see if the treatment is safe and useful for the right type of refractive error.
Beijing, Beijing MunicipalityAges 7–18 - NCT05869682RecruitingPhase 2
Bright light therapy for fatigue and depression in prostate cancer
This Phase 2 study tests whether a “bright white light” intervention can reduce cancer-related fatigue and depression in people with advanced prostate cancer receiving hormone-based treatment. If it works, it could improve day-to-day well-being while you’re on standard cancer therapies.
Duarte, CaliforniaAges 60 years+
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Common questions
- Are there clinical trials for light?
- Yes. Clin2 currently lists 277 recruiting light studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a light trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a light trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.