Clinical trials
Mental Health clinical trials
Below are recruiting mental health clinical trials, each written for real people, not researchers. We’re tracking 725 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06788886Recruiting
Breathing practice for brain and mental health in cancer and other illnesses
This study tests a simple breathing practice to see if it can improve brain health and mental well-being for people with cancer, multiple sclerosis, or their caregivers. You will do light exercises and answer questionnaires, and some participants will also have an MRI brain scan.
Rochester, MinnesotaAges 18–85 - NCT06795581RecruitingPhase 1
Brain imaging study for alcohol use disorder
This study uses a special brain scan (PET) to look at a protein called PDE4B in people with alcohol use disorder. The goal is to better understand how alcohol affects the brain, which may lead to new treatments.
Bethesda, MarylandAges 18–70 - NCT06798324RecruitingPhase 4
Brain stimulation plus smoking cessation medication for quitting smoking
This trial tests whether combining brain stimulation (tDCS) with a smoking cessation medication (varenicline) helps people quit smoking. You would attend daily visits for two weeks.
Toronto, OntarioAges 18–85 - NCT06802939Recruiting
Personalized brain stimulation for voices in schizophrenia
This trial tests a targeted brain stimulation method (rTMS) using brain imaging to treat persistent auditory hallucinations that haven't improved with medication. It may help people with schizophrenia who continue to hear voices despite trying multiple antipsychotics.
ShanghaiAges 13–55 - NCT06804694Recruiting
Technology-based support for young adults with type 1 diabetes distress
This study tests a special program that combines technology and a care team to help young adults with type 1 diabetes who feel stressed or overwhelmed by their diabetes. The goal is to see if this approach is helpful and manageable for participants.
Toronto, OntarioAges 18–29 - NCT06809166RecruitingPhase 4
Contrave for weight loss in adults with obesity
This study tests whether a weight loss medication called Contrave can help adults with obesity lose weight by changing how their body uses energy and handles food. If you qualify, you will take Contrave and be monitored for several months.
Ottawa, OntarioAges 18–64 - NCT06823492Recruiting
Early life and brain study
This study looks at how your early life experiences may affect your brain and behavior. You would visit the University of Manchester for assessments and help researchers understand these connections.
ManchesterAges 18–25 - NCT06828276Recruiting
Online therapy for Farsi and Dari speaking young migrants
This study tests if a culturally adapted online therapy program helps reduce anxiety and depression in young Farsi or Dari speaking migrants. You would use your computer or phone for 6 to 10 weeks at home.
StockholmAges 15–29 - NCT06836323Recruiting
Moral distress and resilience in neonatal care providers
This study looks at how moral distress and personal resilience affect the mental health of healthcare workers who care for newborn babies. By answering surveys, you can help researchers understand these challenges and find ways to support staff.
BernAges Any age - NCT06845124RecruitingPhase 2
Testing CBD and naltrexone for alcohol craving
This trial is testing if taking cannabidiol (CBD) plus naltrexone can reduce alcohol craving in people with alcohol dependence. Naltrexone is already used to help with alcohol cravings, and CBD may add extra benefit.
Wiesloch, Baden-WurttembergAges 18–70 - NCT06854367Recruiting
Comparing fast vs. standard brain stimulation for depression in older adults
This study tests if a faster form of brain stimulation (accelerated theta burst stimulation) works as well as the standard version for treating depression in adults 60 and older. It may help those who haven't gotten relief from antidepressant medications.
Toronto, OntarioAges 60 years+ - NCT06871397Recruiting
Online support program for well-being in early pregnancy
This study tests an online program designed to help pregnant women feel better emotionally and mentally. It includes lessons and support you can access from your phone.
Reus, TarragonaAges 18 years+ - NCT06874205RecruitingPhase 1
Imaging a brain protein in healthy volunteers
This study tests a special imaging agent called 11C-JMJ-129 to see how it behaves in the brain and body of healthy volunteers. The goal is to better understand a brain protein called PDE4D, which may be linked to mood and anxiety disorders.
Bethesda, MarylandAges 18–101 - NCT06888726Recruiting
Brain stimulation for negative symptoms in schizophrenia
This trial tests if a gentle electric current applied to your head can help with negative symptoms (like lack of motivation or emotion). You must have schizophrenia, take a common antipsychotic, and have some ongoing negative symptoms.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06891300RecruitingPhase 2/Phase 3
Ketamine for Suicidal Thoughts in Depression
This study tests if ketamine can help reduce suicidal thoughts in people with major depression. You'll receive ketamine treatment and be monitored closely.
Ottawa, OntarioAges 18–65 - NCT06896071Recruiting
A digital mental health program for teens
This trial tests a one-session digital program designed to help New Zealand teens aged 12–14 feel better mentally. It's a simple online tool you can use once during school.
CambridgeAges 12–14 - NCT06901739Recruiting
Synbiotic for mental health in obesity
This trial tests if a synbiotic (a mix of probiotics and prebiotics) can improve mental health in people with obesity. It may help if you have obesity and also struggle with anxiety or depression.
Valencia, ValenciaAges 18–65 - NCT06906185Recruiting
Trauma-informed support for pregnant veterans with anxiety or depression
This trial tests an online program designed to help pregnant veterans who have experienced trauma and are feeling anxious or depressed. The goal is to see if this program can improve their well-being during pregnancy.
New Orleans, LouisianaAges Any age - NCT06920628RecruitingPhase 1
Brain scan study for long COVID neurological symptoms
This study uses a special PET scan to look at brain inflammation in people with neurological symptoms after COVID-19. It aims to understand how inflammation might be linked to ongoing problems like brain fog or memory issues.
Bethesda, MarylandAges 18–70 - NCT06923423Recruiting
Cognitive processing therapy for drug use and trauma in prison
This study tests if a type of therapy called cognitive processing therapy (CPT) can help people in prison who have both a drug use problem and trauma-related stress. If you qualify, you would receive CPT and be compared to those getting usual care.
Little Rock, ArkansasAges 18 years+ - NCT06937541Recruiting
Family support in dementia mental health wards
This study is about improving care for people with dementia in mental health hospital wards. Researchers want to hear from family carers, people with dementia themselves, and staff to understand experiences and design better support.
LondonAges Any age - NCT06939712Recruiting
Online mental health program for Crohn's patients
This study tests an online program that uses positive psychology to help improve mental health and quality of life in people with Crohn's disease who have mild anxiety or depression. The program is done over the internet, so you can join from home.
Hangzhou, ZhejiangAges 18–75 - NCT06942494Recruiting
CBT Self-Help for Teens with OCD (Family-Based)
This study tests a family-based cognitive behavioral therapy (CBT) self-help program for teens with OCD. It's designed to help you and a parent work together to manage OCD symptoms at home.
Xuhui, Shanghai MunicipalityAges 10–17 - NCT06942559Recruiting
Brain stimulation for treatment-resistant OCD
This trial tests a new type of brain stimulation (TMS) that is timed to your brain's natural rhythms, targeting a part of the brain linked to OCD. It may help people whose OCD has not improved with standard treatments.
Toronto, OntarioAges 18–65
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Common questions
- Are there clinical trials for mental health?
- Yes. Clin2 currently lists 725 recruiting mental health studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.