Clinical trials
Mental Health clinical trials
Below are recruiting mental health clinical trials, each written for real people, not researchers. We’re tracking 701 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06518720RecruitingPhase 2
Psilocybin for Chronic Nerve Pain and Depression
This trial tests whether psilocybin (a psychedelic medication) can help people who have both chronic nerve pain and depression that hasn't responded to standard treatments. The goal is to see if it can reduce pain and improve mood.
Toronto, OntarioAges 18–65 - NCT06528938Recruiting
Accelerated vs. standard TMS for teen depression
This study tests whether a faster, brain-guided form of TMS (called iTBS) can help treat depression in teenagers better than standard TMS. You may qualify if you're 16–19, have tried an antidepressant that didn't work well, and have no medical reasons to avoid TMS or MRI.
Ottawa, OntarioAges 16–19 - NCT06512220RecruitingPhase 2
Psilocybin for treatment-resistant depression brain imaging study
This study tests whether a psilocybin-based treatment can help people with depression that has not improved after trying several antidepressants. You will receive the study treatment and have brain scans to see how it affects brain connections.
Toronto, OntarioAges 18–65 - NCT06513871Enrolling by invitation
Social perception study for ages 16 and up
This study looks at how people understand social situations. It may help us learn more about social thinking in everyday life.
New Haven, ConnecticutAges 16–65 - NCT06497920Recruiting
Brain stimulation for motor skills in autistic adults
This trial tests whether a type of brain stimulation called rTMS can improve motor skills (like coordination and movement) in autistic adults. If you have autism and notice challenges with motor function, this study may help.
Toronto, OntarioAges 18–40 - NCT06513845Enrolling by invitation
Drum circle study for adults
This study is looking at how drumming together in a group may affect people's sense of connection and well-being. You may be able to join if you are 18 or older.
New Haven, ConnecticutAges 18–65 - NCT06513858Enrolling by invitation
Community drum circle for wellness
This study looks at how a community drum circle may affect your wellbeing. It is open to anyone aged 16 and older.
New Haven, ConnecticutAges 16–65 - NCT06513910Recruiting
Studying how social music affects the brain
This trial looks at how listening to music with others changes brain activity. It may help us understand the social benefits of music.
New Haven, ConnecticutAges 16 years+ - NCT06505590Recruiting
Online support for cancer-related fatigue
This trial tests an online support program designed to help people with cancer manage fatigue. If you have had moderate to severe fatigue for at least a week, you may be able to join from home.
VillejuifAges 18 years+ - NCT06505226Recruiting
Music mindfulness study for anxiety and depression
This study tests a music-based mindfulness program to help people with anxiety or depression. It compares the program to a wait list to see if it eases symptoms.
New Haven, ConnecticutAges 18–65 - NCT06484088RecruitingEarly Phase 1
Brain scanning study of frustration in healthy adults
This study looks at how the brain handles frustration in healthy adults using a special brain scanner called magnetoencephalography (MEG). It may help researchers understand normal brain responses to frustration.
Bethesda, MarylandAges 18–55 - NCT06239545Recruiting
JoyPop app for mental health support in young adults
This trial tests a mobile app called JoyPop designed to help young adults manage their mental health while they wait for services. It aims to see if using the app can improve well-being and reduce distress.
Thunder Bay, OntarioAges 18–25 - NCT06239519Recruiting
JoyPop mobile app for youth mental health
This trial is testing a mobile app called JoyPop to help youth with their mental health while they wait for counselling. Participants use the app for a few weeks and share feedback.
Thunder Bay, OntarioAges 12–17 - NCT06462196Recruiting
Study of Depression, Bipolar Disorder & Suicide Risk
This study looks at how depression, bipolar disorder, and suicide risk naturally change over time. It aims to better understand these conditions so doctors can improve treatments.
Bethesda, MarylandAges 18–120 - NCT06471816Recruiting
A kindergarten program to support children's mental health
This study tests a simple conversation-based program in kindergartens to support young children's emotional well-being. If your child is in their third last year of kindergarten, you may be able to join.
BergenAges 2–3 - NCT06456307Recruiting
Stepped care for mood and anxiety during pregnancy
This study tests a step-by-step approach to help pregnant women who are feeling anxious or down. If you are at least 28 weeks pregnant and feeling stressed, worried, or sad, the study will offer you support and check on how you are doing.
NairobiAges 14 years+ - NCT06457230Recruiting
Brain stimulation for methamphetamine use disorder
This study tests a new type of non-invasive brain stimulation (transcranial magnetic stimulation) that targets the cerebellum and prefrontal cortex to help people with methamphetamine use disorder. It aims to see if this treatment can reduce cravings and improve outcomes.
Shanghai, Shanghai MunicipalityAges 18–60 - NCT06456983Recruiting
Maintenance ECT for hard-to-treat schizophrenia
This trial tests if regular electroconvulsive therapy (ECT) can help people whose schizophrenia has not improved with clozapine or who cannot take clozapine. Researchers will see if maintenance ECT helps prevent symptoms from returning.
AachenAges 18–75 - NCT06456762Recruiting
Text-messaging support for parents after child's ER visit
This study tests whether a text-messaging program can help parents support their child after a mental health emergency room visit. If you join, you'll receive texts with tips and resources to help your child transition to outpatient care.
Nashville, TennesseeAges 18 years+ - NCT06445101Enrolling by invitation
Vital@Work: Preventing mental health issues at work
This trial tests a program called Vital@Work that helps prevent mental health problems at work. The study is open to employees of organizations that join the program.
AmsterdamAges 18 years+ - NCT06430853Enrolling by invitation
Pregnancy support study for moms with anxiety or depression
This study tests if a mental health program during pregnancy can help mothers with past or current anxiety or depression. You'll get support and you may feel better and have a healthier pregnancy.
Stanford, CaliforniaAges 18 years+ - NCT06153316Recruiting
How school shootings affect students and staff
This study looks at how experiencing a school shooting impacts students, teachers, and principals. It compares schools that had a shooting to those that did not, to understand the effects on wellbeing.
New York, New YorkAges 11–65 - NCT06399991Recruiting
Improving mental health care in Malawi clinics
This study is testing a new way to help clinics in Malawi better support patients with mental health needs. If you are an adult patient at a participating clinic who has recently had symptoms of depression or anxiety, you may be eligible.
ChiradzuluAges 18 years+ - NCT06389565Recruiting
Change My Story: A mental health program for young adults with HIV
This study tests a mental health program to help young people living with HIV who feel down or depressed. It's designed to see if talking through your story can help you feel better and function day-to-day.
Ibadan, Oyo StateAges 16–29
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Common questions
- Are there clinical trials for mental health?
- Yes. Clin2 currently lists 701 recruiting mental health studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.