Clinical trials
Mental Health clinical trials
Below are recruiting mental health clinical trials, each written for real people, not researchers. We’re tracking 701 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06378541Recruiting
Smartphone app for suicide prevention in veterans
This study tests if a smartphone app can help veterans who are hospitalized after a suicidal crisis. The app is designed to support mental health and prevent future crises.
Ann Arbor, MichiganAges 18 years+ - NCT06370988Recruiting
Theta-burst stimulation for bipolar depression
This study tests a type of brain stimulation (theta-burst TMS) to see if it helps improve depression in people with bipolar disorder. It might be a good option if you have tried medication but still feel depressed.
Toronto, OntarioAges 18–65 - NCT06373484Recruiting
Matching treatment for kids with disruptive behavior and their parents
This study aims to find the best treatment approach for children with disruptive behavior by matching them to either group or individual therapy. It could help if your child struggles with behavior like defiance or conduct issues, and you're willing to participate in treatment.
Toronto, OntarioAges 6–12 - NCT06067165Recruiting
Online emotion-regulation program for teens
This trial tests an online program called POET that helps teens learn skills to manage emotions. The program includes a parent part, so a guardian will also be involved. It may be a good option if you are between 12 and 17, have mild to moderate mental health struggles, and are not already in another treatment.
StockholmAges 12–17 - NCT06346028RecruitingPhase 4
TMS for quitting smoking
This study tests whether a brain stimulation therapy called transcranial magnetic stimulation (TMS) can help people quit smoking. It is for adults who smoke daily and are willing to try TMS as a treatment.
Toronto, OntarioAges 18–70 - NCT05838404Recruiting
Program to support mental health during early pregnancy
This study tests an intervention meant to improve mental health for people during pregnancy, starting in the first part of pregnancy. You might be able to join if you are already receiving prenatal care and speak English or Spanish.
New Orleans, LouisianaAges 18 years+ - NCT06290778Enrolling by invitation
Mental health prevention training for fire fighter trainees
This study tests a program where peers teach emotion regulation skills to help prevent mental health issues in new fire fighters. You would be asked to complete surveys and attend training sessions.
Waco, TexasAges 21 years+ - NCT06233344RecruitingPhase 2
Mindfulness and psilocybin study for healthy adults
This study tests whether combining mindfulness training with a single dose of psilocybin (a psychedelic found in certain mushrooms) can help healthy adults. It aims to explore how these two approaches together might improve well-being.
Los Angeles, CaliforniaAges 25 years+ - NCT06248203Recruiting
Teacher-led mental health support for teens in Darjeeling
This trial tests a program in which teachers get extra training to support students with emotional or behavioral challenges in low-cost private schools in Darjeeling. It aims to see if teachers can make a positive difference for these teens.
Darjeeling, West BengalAges 13 years+ - NCT06246214Recruiting
Biological rhythms for perinatal mental health
This study looks at whether understanding your body's daily rhythms (like sleep and activity) can help treat depression after childbirth. If you are 4-6 weeks postpartum and have been diagnosed with postnatal depression, this could be an option for you.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06141408Recruiting
PrEP for Black men in Prince George's County
This study looks at whether a new program can help Black men in Prince George's County, Maryland, start or stay on PrEP, a daily pill that prevents HIV. If you're HIV-negative and at risk, this could be a way to protect your health.
Fairfax, VirginiaAges 18 years+ - NCT06222632Enrolling by invitation
MIND diet and forest bathing for heart and mind
This study tests whether a brain-healthy diet (MIND diet) combined with relaxing walks in nature (forest bathing) can help protect your heart and improve your mood. It is for Chinese adults aged 50–75 who have high cholesterol and some anxiety.
Hong KongAges 50–75 - NCT06178328Recruiting
Online mental health program for Canadian adults
This study is testing a short online mental health program for adults in Canada who are seeking help. It aims to see if the program helps people feel better.
Regina, SaskatchewanAges 18 years+ - NCT06145477Recruiting
Parenting support for preschoolers in Head Start
This study tests a new virtual program to help parents manage their preschool child's behavior and support their mental health. It is for families in Baltimore City Head Start programs.
Baltimore, MarylandAges 18–99 - NCT06152705Recruiting
fMRI-Guided vs. Standard Brain Stimulation for Depression
This study compares two types of repetitive transcranial magnetic stimulation (rTMS) to treat depression. One type uses a brain scan (fMRI) to guide the treatment, while the other uses a standard approach. It may help people whose depression hasn't improved with medication.
Ottawa, OntarioAges 18 years+ - NCT06129903Recruiting
Early psychiatric help for people with sarcoma
This study tests if getting a psychiatric consultation soon after a sarcoma diagnosis can improve mental health and quality of life. If you have a new sarcoma and need surgery at MSK, you may be able to join.
Basking Ridge, New JerseyAges 18 years+ - NCT06086366Recruiting
Brain scan study for depression after COVID-19
This study uses brain scans to understand depression that starts soon after COVID-19. Researchers want to see if there are changes in brain chemistry related to depression, and you may help find new treatment targets.
Toronto, OntarioAges 18–75 - NCT04373629Recruiting
Testing how flexible appearance worries may change in BDD
This study looks at whether training can change how people with body appearance worries (including body dysmorphic disorder) perceive faces or the head. It may help researchers understand new ways to reduce distress related to these concerns.
Toronto, OntarioAges 18–40 - NCT04922762Recruiting
Exercise program study for blood vessel function in mental health
This study looks at how an exercise program affects blood vessel function (“vascular function”) in people with certain mental health conditions, and compares them to people without those symptoms. It may help researchers understand whether exercise could improve heart and blood vessel health alongside mental health symptoms.
Richmond, VirginiaAges 18–35 - NCT06047301Recruiting
Pathways: A hope program for advanced lung cancer patients
This study tests a program called 'Pathways' that helps people with advanced lung cancer set personal goals, manage mental health, and improve quality of life. It's for those who are already receiving IV cancer treatment and are feeling some distress.
Lexington, KentuckyAges 18 years+ - NCT06032377Recruiting
Online therapy for sleep and brain health in older adults
This study tests an online talk therapy program (CBT) to help older adults with both sleep troubles and mild memory or thinking concerns. It's done from home, and aims to improve sleep and brain health.
Ottawa, OntarioAges 60–99 - NCT06037954Recruiting
Mental health support for older adults with cancer
This study offers mental health care for older adults (65+) with breast, colorectal, lung, or prostate cancer who are getting treatment or recently finished. It aims to help people who are also feeling depressed.
New York, New YorkAges 65 years+ - NCT06038721Recruiting
Unified Protocol for kids with emotional concerns
This trial tests a program called Unified Protocol for children ages 7–17 who have emotional difficulties like anxiety, depression, trauma, or obsessive-compulsive symptoms. It aims to help kids and their parents learn skills to manage these feelings together.
Coral Gables, FloridaAges 7–17 - NCT04882839RecruitingPhase 2
Therapy with psilocybin for severe OCD symptoms
This Phase 2 study tests whether psilocybin-assisted psychotherapy can reduce symptoms in adults with severe, treatment-resistant OCD. It also focuses on safety and whether this approach is practical to run.
BeershebaAges 18–65
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Common questions
- Are there clinical trials for mental health?
- Yes. Clin2 currently lists 701 recruiting mental health studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.