Clinical trials
Metabolism clinical trials
Below are recruiting metabolism clinical trials, each written for real people, not researchers. We’re tracking 1,078 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04371042Recruiting
Study of liver disease and genes in people with fatty liver
This study collects information about metabolic and unexplained (cryptogenic) liver disease and looks at “omics” tests, which are lab tests that measure patterns in blood or tissue to learn what drives the disease. It may help researchers better understand fatty liver and related serious complications, like liver scarring and liver cancer.
Roma, Rome/lazio/italyAges 18 years+ - NCT04573283Recruiting
Study of fatty liver in adults in China
This study follows adults with fatty liver to learn more about how it progresses and what patterns are common. It may help improve future ways of identifying and monitoring fatty liver.
Guangzhou, GuangdongAges 18–80 - NCT04575844RecruitingPhase 4
Exercise and GLP-1 to improve insulin and muscle blood flow
This study looks at whether doing exercise and a GLP-1 medicine (liraglutide or similar) can improve how your body uses insulin and how blood flows to your muscles. It is aimed at adults with metabolic syndrome who do not already have diabetes.
Charlottesville, VirginiaAges 21–60 - NCT04812314Recruiting
Study how exercise changes body fat and metabolism
This study looks at how starting exercise changes the structure and function of body fat. It may help you understand how exercise affects things like cholesterol and blood sugar, even if you’re not currently exercising regularly.
Ann Arbor, MichiganAges 18–40 - NCT04873258Recruiting
Test a non-invasive tool to screen for fat-related liver disease
This study looks at a new non-invasive screening method to predict metabolic dysfunction–associated steatotic liver disease (MASLD), a condition where fat builds up in the liver. The goal is to help identify people who may be at risk without needing invasive tests.
London, LondonAges 18–80 - NCT04880356Recruiting
Study of very rare inherited brain diseases over time
This study follows adults over time who have a very rare inherited brain disease, or whose illness seems like it may run in families. The goal is to better understand these conditions and how they progress.
Milan, MilanoAges 18 years+ - NCT04912648Recruiting
Study of metabolic risk and androgens in Irish women
This study looks at how hormones called androgens may relate to “metabolic risk” (things like blood sugar and weight-related health) over time. It mainly needs healthy adult women who can avoid certain medications during the weeks before starting.
DublinAges 18 years+ - NCT06007404Recruiting
Understanding metabolism and inflammation in teens
This study looks at how metabolism and inflammation relate to diabetes risk in teenagers. It may help researchers understand why some teens develop type 2 diabetes.
Ann Arbor, MichiganAges 14–18 - NCT05197309Recruiting
Metabolic diet to help prevent relapse in anorexia
This study tests whether a specific diet can help people with anorexia nervosa stay well and avoid relapse after weight restoration. It focuses on “metabolic” (energy and blood sugar-related) effects, checked with blood work and regular visits.
New York, New YorkAges 18–40 - NCT05275608Recruiting
Low-carb diet effects in people with metabolic syndrome
This trial studies whether a very low-calorie, low-carb diet (VLCKD) can improve metabolic health in adults with metabolic syndrome, fatty liver, and type 2 diabetes. It may help lower blood sugar and improve related health markers if you fit their specific diabetes and liver/kidney criteria.
Novara, ItalyAges 25–65 - NCT05363059Recruiting
Bariatric surgery compared with standard treatment for metabolic syndrome
This trial compares bariatric (weight-loss) surgery with medical (non-surgery) treatment in people with metabolic syndrome, a cluster of risk factors that can affect heart and blood sugar. It aims to see which approach improves these health risks and overall metabolism.
Chongqing, Chongqing MunicipalityAges 18–65 - NCT05398783Recruiting
Study of how metabolism and body composition change over time
This natural history study follows people to understand how metabolism and body composition vary in health and disease. It may help researchers better measure metabolic changes and understand who is at risk as health and treatments change.
Bethesda, MarylandAges 2–99 - NCT05413278Recruiting
Helps teens with inherited metabolism conditions move to adult care
This study tests a targeted approach to help teenagers with inherited metabolism conditions successfully transfer from children’s to adult healthcare. It may help families feel more confident and reduce problems during the handoff to adult services.
ViennaAges 14–25 - NCT05519475RecruitingPhase 2
Gene-silencing medicine trial for adults with MASH and liver scarring
This Phase 2 study tests a gene-silencing treatment to improve chronic liver disease called MASH, especially in people with certain genetic risk. You may be eligible if you have MASH with moderate-to-advanced scarring and specific test results, and if other liver causes and recent substance/alcohol issues don’t apply.
Chandler, ArizonaAges 18–75 - NCT05543083Recruiting
Therapy plus exercise for teens at risk of type 2 diabetes
This trial tests whether a combination of coaching (cognitive-behavioral therapy) and exercise can improve mood and help teens who are at higher risk for type 2 diabetes. It may be especially helpful if you’re dealing with depression symptoms and a family history of type 2 diabetes.
Aurora, ColoradoAges 12–17 - NCT05544266Recruiting
Study rare diabetes patterns to better guide diagnosis
This study looks at people who may have a “non-typical” form of diabetes, including rare genetic causes or unusual symptoms. It may help your care team understand what type of diabetes you have and whether specific genetic testing could explain it.
Aurora, ColoradoAges Any age - NCT05564273Recruiting
Viome nutrition program for people with metabolic health issues
This trial tests whether a personalized Viome nutrition program can improve metabolic health (such as higher fasting insulin or glucose). You would use their app and follow the program, while researchers monitor health outcomes over time.
Bothell, WashingtonAges 25–75 - NCT05574153Recruiting
Testing heart oxygen reserve in metabolic syndrome and healthy adults
This study measures how much oxygen your heart can use during stress and at rest using an MRI scan. It compares people with metabolic syndrome (a cluster of health risks) to people without those risks, to understand differences in heart function.
Montreal, QuebecAges 18–80 - NCT05648214RecruitingPhase 1/Phase 2
Testing a new liver medicine in people with fatty liver
This early-phase study tests whether ALN-PNP is safe and well tolerated, first in healthy adults and then in adults with MASLD (fatty liver disease). If you have MASLD, it may help researchers learn whether this medicine is a promising option for treating liver fat buildup.
Glendale, CaliforniaAges 18–75 - NCT05702853RecruitingPhase 1/Phase 2
CAR T-cell therapy after CD34 selection for CD19 lymphoma or CLL
This Phase 1/2 study tests a customized type of immune cell treatment (CD19 CAR T-cells) for people with certain relapsed or hard-to-treat lymphomas or CLL/SLL. It aims to improve control of disease by targeting the CD19 marker on cancer cells.
Charleston, South CarolinaAges 18 years+ - NCT05802121RecruitingEarly Phase 1
Testing a gut bacteria supplement side effects during prostate hormone therapy
This early-phase study looks at how changing gut bacteria (especially Akkermansia) affects metabolic side effects in men starting prostate hormone therapy (ADT). It may help researchers understand how to reduce or manage side effects for people on ADT.
London, OntarioAges 18 years+ - NCT05859022Recruiting
Bariatric treatment methods compared for diabetes and metabolism
This trial compares a less invasive heart/artery-based bariatric treatment (bariatric arterial embolization) with standard weight-loss surgery to see how they affect metabolism and type 2 diabetes. You might be considered if you have obesity with type 2 diabetes and have not had prior bariatric surgery.
LisbonAges 18–75 - NCT05905965RecruitingPhase 3
Higher versus standard empagliflozin dose for metabolic syndrome
This trial tests whether a higher dose of empagliflozin works better than the standard dose to treat metabolic syndrome. It may help improve blood sugar and cholesterol-related risk factors in people who meet the trial’s criteria.
Bydgoszcz, Cuiavian-PomeranianAges 18–85 - NCT05910840Recruiting
Online training for teens with type 1 diabetes moving to adult care
This trial tests an online training program to help teens with type 1 diabetes make the transition from pediatric care to adult care. It may help you feel more prepared for changes in how diabetes is managed as you get older.
GatineauAges 14–16
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Common questions
- Are there clinical trials for metabolism?
- Yes. Clin2 currently lists 1,078 recruiting metabolism studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metabolism trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metabolism trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.