Clinical trials
Metabolism clinical trials
Below are recruiting metabolism clinical trials, each written for real people, not researchers. We’re tracking 1,079 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05586867Recruiting
Blood testing study in people on hemodialysis
This study looks at blood markers related to iron and other body processes (like minerals, liver function, and inflammation) in people receiving hemodialysis. The results may help doctors better understand what affects health in dialysis patients.
Quincy-sous-SénartAges 18 years+ - NCT06337864Recruiting
Large neutral amino acids for adults with classical PKU
This study tests whether a specific mix of large neutral amino acids (LNAAs) can help adults with classical PKU by lowering phenylalanine levels in the brain. It includes an MRI and PET scan to see how the treatment affects brain activity.
CopenhagenAges 18–50 - NCT06986447Enrolling by invitation
Non-invasive tests for serious liver disease
This study is testing whether advanced imaging and other non-invasive methods can properly identify people with significant liver scarring due to metabolic liver disease or alcohol-related liver disease. It may help find better ways to track liver health without repeated needle biopsies.
Chandler, ArizonaAges 18–80 - NCT06374875RecruitingPhase 4
Does metabolic surgery reduce liver scarring?
This study tests if weight loss surgery can improve liver fibrosis (scarring) in people with obesity and advanced liver disease. It may help those considering surgery to know if their liver health can get better.
Phoenix, ArizonaAges 18–75 - NCT03994367Recruiting
Study of diet protein types and how they affect blood sugar
This study looks at how eating more or different types of proteins (animal vs plant) may change your blood sugar handling. It mainly targets adults who eat relatively little protein and have no diabetes.
Columbia, MissouriAges 21–70 - NCT07699380RecruitingPhase 2
Metabolic study to improve insulin sensitivity in type 1 diabetes
This study tests a new medication to see if it can improve how your body responds to insulin and boost your cells' energy (mitochondrial function). It is for adults with type 1 diabetes who are already on insulin and have good overall health.
Seattle, WashingtonAges 18–69 - NCT06092346Recruiting
Understanding rare purine and pyrimidine metabolism disorders
This study aims to learn more about rare disorders of purine and pyrimidine metabolism (DPPM), which can affect the brain, immune system, kidneys, and muscles. Researchers will study people with these disorders, their family members, and healthy volunteers to better understand the condition over time.
Bethesda, MarylandAges 1 month–100 years - NCT06836609RecruitingPhase 1/Phase 2
Study of a new drug for fatty liver disease (MASLD/MASH)
This study tests a new drug called ALN-CIDEB for people with fatty liver disease (MASLD or MASH). The goal is to see if it can reduce liver fat and improve liver health. You may qualify if you have a higher BMI and evidence of liver fat on imaging tests.
Chandler, ArizonaAges 18–65 - NCT07043166Recruiting
Heart, kidney, and metabolic health study in Shanghai
This study looks at the link between heart, kidney, and metabolic health in adults living in Shanghai. It follows people who were part of an earlier health study to see how their health changes over time.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07093346Recruiting
Pectin supplement for fatty liver disease
This study tests whether a pectin supplement (a fiber found in fruits) can reduce inflammation and improve liver and metabolic health in people with fatty liver disease (MASLD). You might be eligible if you have MASLD, a healthy weight range, and can avoid certain medications and foods.
NottinghamAges 18 years+ - NCT07330297Recruiting
Breath test for metabolic syndrome and obesity health
This study uses a breath test to see if it can tell the difference between people with metabolic syndrome, those with obesity but otherwise healthy, and healthy controls. It aims to find a simple way to check metabolic health without blood draws.
MoscowAges 18 years+ - NCT07781384Enrolling by invitation
Vibrotactile device for resting metabolic rate
This study tests a new wearable device that uses gentle vibrations (vibrotactile technology) to see if it can change your resting metabolic rate — the number of calories your body burns at rest. It may help with weight management or metabolism.
Tyrone, GeorgiaAges 18–85 - NCT07613307RecruitingPhase 3
Study of a new pill for type 2 diabetes during Ramadan fasting
This study tests an oral medication called orforglipron to see if it safely helps people with type 2 diabetes manage their blood sugar while they fast during Ramadan. You may be a good fit if you are planning to fast and your diabetes is not too severe.
AgraAges 18–65 - NCT06107959Recruiting
Metabolism changes after bone or joint surgery
This study measures how your metabolism (how fast your body burns energy) changes after orthopedic surgery (surgery on bones or joints). It may help doctors understand how to better support recovery.
Kansas City, KansasAges 15 years+ - NCT07450144Recruiting
Chatbot to Help Reduce Alcohol in Fatty Liver Disease
This study tests a chatbot that helps people with fatty liver disease reduce how much they drink. If you drink regularly and are ready to change, this tool could support you.
Hong KongAges 18 years+ - NCT07737561Recruiting
Exercise test for heart, kidney, and metabolic health
This study looks at how blood pressure and artery stiffness respond to exercise in people with heart, kidney, and metabolic problems. It may help doctors better understand your condition.
KaramanAges 18 years+ - NCT07096011Recruiting
Studying obesity risks in young infants
This study looks at very young babies to understand early signs of obesity risk. If your baby is under 4 months old and mainly drinks breastmilk, they may help researchers learn more about how body growth and feeding relate to health later in life.
Baton Rouge, LouisianaAges 2 weeks–4 months - NCT07013916Recruiting
Fructose and liver health in fatty liver disease
This study looks at how a sugar called fructose affects inflammation and metabolism in people with a type of fatty liver disease called MASH. It aims to find out if fructose plays a role in making the disease worse.
LondonAges 45–65 - NCT07716488Recruiting
Screening for high cholesterol in children with chronic conditions
This study screens children and teens with certain chronic conditions (like heart defects or inflammatory bowel disease) for early signs of high cholesterol or other lipid problems. The goal is to find and manage these risks sooner.
JenaAges 6–18 - NCT05933707Recruiting
Study tiny vesicles and how they affect insulin
This study looks at how very small particles in the body (“extracellular vesicles”) relate to insulin action and how the body handles sugar. It may help researchers understand why some people have better or worse insulin responses.
St Louis, MissouriAges 25–55 - NCT07707778Enrolling by invitationPhase 4
Tirzepatide for Weight and Aging in People with HIV
This trial tests whether a weight-loss medicine called tirzepatide can slow biological aging and improve metabolism in people with HIV who are already on effective treatment. It may help you reduce weight and possibly reverse some signs of aging.
TaipeiAges 18 years+ - NCT03451968Recruiting
Amino acid levels in long ICU stays after surgery or trauma
This study measures amino acids (building blocks from food) in people who are critically ill after surgery or trauma while they stay in the ICU for more than a week. It also compares results with healthy adults to better understand how critical illness affects nutrition needs.
Petah TikvaAges 18 years+ - NCT05085704Recruiting
Brain scans to study metabolism in healthy and diabetic people
This study uses MRI brain scans at different strengths to measure how the brain uses energy (metabolism) in health and in people with genetically confirmed G1D. It may help researchers understand brain energy changes related to metabolic disease and diabetes.
New York, New YorkAges 16–80 - NCT05806801Recruiting
Study how weight loss changes the body with or without exercise
This study looks at how your metabolism (how your body uses energy and controls blood sugar/fats) changes during weight loss, comparing weight loss alone versus weight loss plus exercise. It may help researchers understand what body changes happen with different approaches and why.
Ann Arbor, MichiganAges 18–40
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Common questions
- Are there clinical trials for metabolism?
- Yes. Clin2 currently lists 1,079 recruiting metabolism studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metabolism trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metabolism trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.