Clinical trials
Microbial Colonization clinical trials
Below are recruiting microbial colonization clinical trials, each written for real people, not researchers. We’re tracking 33 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06805994RecruitingPhase 1
Restoring infant nose bacteria after staph treatment
This study tests whether giving a nasal spray of healthy bacteria to infants can restore good germs in the nose after they receive mupirocin ointment to treat Staph aureus. It aims to bring back a healthy nasal microbiome.
Baltimore, MarylandAges birth–60 years - NCT06149585Recruiting
Bacteria changes in gum disease patients getting all dental implants
This study looks at how bacteria in your mouth change when all your teeth are removed and replaced with dental implants. If you have severe gum disease and need all your teeth extracted, joining this trial could help researchers understand your healing process.
Cleveland, OhioAges 21 years+ - NCT06390696Recruiting
Sand play for eczema: a biodiversity study
This study looks at whether playing in sand with different types of natural materials (to increase your contact with harmless microbes) can improve eczema symptoms. You would stop using your usual eczema creams during the trial to see if the sand play alone helps.
Helsinki, UusimaaAges 2–5 - NCT05193162Recruiting
Study of gut microbes using stored pancreatic tissue
This study looks at differences in microbes (tiny organisms) using previously collected pancreatic tissue samples. It may help doctors understand how the microbiome relates to pancreatic diseases like pancreatic cancer.
ShanghaiAges 5–85 - NCT06970262Recruiting
Fecal transplant for tough lung infections on a ventilator
This study tests whether a treatment called fecal microbiota transplantation (FMT) can help clear stubborn lung infections (MDRO) in people who are in the ICU on a ventilator. The goal is to see if FMT can improve recovery and reduce the risk of further organ problems.
WuhanAges 18–70 - NCT04447742Recruiting
Study of how healthy babies’ gut microbes develop from birth
This study follows pregnant people from about 20 weeks until delivery, to understand how gut microbes (tiny organisms in the intestines) develop in healthy babies. It may help researchers learn how early-life gut development affects health later on.
BernAges 18–45 - NCT04735835Recruiting
Personalized diet testing using ZOE app and blood samples
This trial studies how different food compositions affect your body, using the ZOE testing program plus meals you eat and blood samples you collect. It may help you learn more about what foods work best for you, especially if you have a long-term health condition.
Needham, MassachusettsAges 18 years+ - NCT04966793Recruiting
Study bacteria patterns in bronchiectasis and how they change
This study looks at how bacteria live in the lungs of people with bronchiectasis and how they may adapt over time. It may help researchers understand why infections keep coming back and how to better manage chronic lung colonization.
Hangzhou, ZhejiangAges 18–79 - NCT05127252Recruiting
Study how gut bacteria may affect time to pregnancy
This study looks at whether differences in the gut (microbiome) are linked to how long it takes to get pregnant and pregnancy outcomes. It may help researchers understand who might benefit from future microbiome-focused approaches.
Stockholm, HuddingeAges 18–40 - NCT05275335Recruiting
Study how germs in burn wounds are best identified
This study compares two ways of finding germs (microbes) in burn wounds: traditional tissue swabs/cultures versus a newer DNA-based method. It may help improve how clinicians understand burn infections and tailor care.
Galveston, TexasAges 18–100 - NCT05401292RecruitingPhase 4
Skin prep for planned foot and ankle surgery
This trial studies whether a specific skin-prep approach before elective (planned) foot and ankle surgery can help prevent infection. You may be able to take part if your surgery is not for an injury and you meet the age and health requirements.
Columbia, MissouriAges 18 years+ - NCT05414994Recruiting
Study eye bacteria in healthy and eye disease
This study compares the tiny living organisms (“ocular microbiome,” meaning eye-surface bacteria) in different eye conditions. It may help researchers understand how these eye bacteria relate to diseases and why some people develop problems with vision.
Nashville, TennesseeAges 18 years+ - NCT05432362Recruiting
Energy sensing brain study in depression and weight groups
This study tests how the brain and body respond to “energy sensing” in people with depression and in people with different body weights. You may be asked to do assessments and follow specific health and diet rules so the researchers can compare groups.
Graz, StyriaAges 18–40 - NCT05502380RecruitingPhase 3
Antibiotic prevention study for high-risk bone and spine surgeries
This Phase 3 study tests whether giving a broad set of preventive antibiotics before certain high-risk orthopedic surgeries lowers the chance of serious wound or bone infection. It mainly targets people who have contaminated wounds, tumor-related surgery, or known high-risk germs on the skin.
ZurichAges 18 years+ - NCT05524649Recruiting
Probiotics for healthy newborns’ poop bacteria balance
This study looks at whether giving probiotics to healthy newborns changes the bacteria in their stool. It may help researchers understand early gut health, but it is only for babies who meet specific health and timing requirements.
Alcaldía Coyoacán, PueblaAges 1 day–3 months - NCT05561504Recruiting
Study of stomach bacteria resistance in adults
This study looks at how common a stomach bacteria infection is and which antibiotics still work. You may help researchers by providing consent for related study participation and sample tracking.
MunichAges 18 years+ - NCT05603650Recruiting
Mouthwash study for healthy bacteria in your mouth and gut
This study tests how a mouthrinse changes the helpful bacteria in your mouth and stomach/gut. You may need several visits and phone follow-ups to see how your microbiome shifts over time.
Irvine, CaliforniaAges 18 years+ - NCT05743374Recruiting
Diet changes with micronutrients for ulcerative colitis
This trial looks at whether changing your diet with certain vitamins or minerals (micronutrients) and other diet additives can improve health in people with moderately active ulcerative colitis. You may be asked to follow a specific diet plan, while your symptoms and medication stability are monitored.
Malmö, Skåne CountyAges 18 years+ - NCT05923333Recruiting
Breastfed infants of HIV-exposed mothers get a probiotic
This study gives a specific probiotic (from B. infantis) to babies born without HIV to see if it can improve the baby’s early immune health. It focuses on babies who are HIV-exposed because their mother has HIV and plans to exclusively breastfeed for the first 6 months.
Cape TownAges birth–50 years - NCT05963711Recruiting
Study penis microbiome in partners during vaginal microbiome treatment
This study looks at how the bacteria on a man’s penis may change during a woman’s vaginal microbiome transplant (VMT) for recurrent bacterial vaginosis (BV). You may be asked to follow condom and “decolonization” steps to help the researchers understand what works and why.
JerusalemAges 18 years+ - NCT05966649Recruiting
Synbiotics for preventing preterm birth in higher-risk pregnancies
This trial tests whether taking synbiotics (a mix of “good” probiotics and “food” for them) can help lower the chance of going into labor too early. It’s for pregnant people with certain risk factors for preterm birth, and it compares outcomes while you follow the study plan.
Edegem, AntwerpenAges 18 years+ - NCT06018792Recruiting
New blood test for faster sepsis diagnosis in children
This trial tests a new, faster way to find bacteria in the blood of children with suspected sepsis. It uses a molecular test that may give results sooner than standard cultures, helping doctors treat infections more quickly.
AmsterdamAges birth–18 years - NCT06177184Recruiting
Donor milk for full-term cesarean-born babies
This study tests whether giving donor breast milk to full-term babies born by C-section can improve their gut health. If your baby was born by C-section and you plan to breastfeed, this trial may be a good fit.
Calgary, AlbertaAges 9 months+ - NCT06283355RecruitingPhase 1
Comparing one vs. multiple nasal treatments in NICU babies
This study tests whether giving one versus multiple doses of a special nasal treatment (called nasal microbiota therapy, or NMT) changes the types of helpful bacteria in your baby's nose. The goal is to see if the treatment keeps bad bacteria, like staph, from growing.
Baltimore, MarylandAges birth–60 years
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Common questions
- Are there clinical trials for microbial colonization?
- Yes. Clin2 currently lists 33 recruiting microbial colonization studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a microbial colonization trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a microbial colonization trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.