Antibiotic prevention study for high-risk bone and spine surgeries
Part of Infections clinical trials.
This Phase 3 study tests whether giving a broad set of preventive antibiotics before certain high-risk orthopedic surgeries lowers the chance of serious wound or bone infection. It mainly targets people who have contaminated wounds, tumor-related surgery, or known high-risk germs on the skin.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 or older
- You are having an orthopedic operation for an open fracture/wound, a wound revision, or a tumor/spine-related surgery
- Your surgeon expects to collect bacteria samples during the operation
- You have skin bacteria that are resistant to multiple antibiotics (multidrug-resistant Gram-negative)
- You are able to complete the study and planned follow-up is at least 6 weeks after enrollment
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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