Clinical trials · Massachusetts
Mitral Valve Disease clinical trials in Massachusetts
We’re tracking 13 recruiting mitral valve disease studies with a site in Massachusetts, each written for real people, not researchers.
Recruiting studies in Massachusetts
- NCT04736667Recruiting
Screening survey for mitral valve treatment planning
This study is for people who did not pass an initial screening for a specific mitral valve procedure called TMVI. It may help the team understand screening results and improve how patients are assessed for the right next steps.
Boston, MassachusettsAges 18 years+ - NCT04029337Recruiting
Transcatheter mitral valve replacement for severe leakage
This study tests a new device that replaces a leaking mitral valve without open-heart surgery. It may help people who have severe mitral valve leakage but cannot safely have standard surgery or some other less invasive valve repairs.
Boston, MassachusettsAges 18 years+ - NCT04408430Recruiting
Valve replacement for severe mitral valve disease in high-risk adults
This trial tests a less-invasive way to treat severe mitral valve problems using a transcatheter valve. It may help people who are too high-risk for standard open-heart mitral surgery by improving symptoms and heart function.
Boston, MassachusettsAges 18 years+ - NCT04688190Recruiting
Registry study for choosing a mitral valve treatment
This study collects and compares real-world results to help doctors choose the best treatment for mitral valve “leakiness.” If you have clinically significant mitral insufficiency and have already had a specific heart procedure screening, your echocardiogram results may be used to understand outcomes over at least a month.
Boston, MassachusettsAges 18 years+ - NCT06387446Recruiting
Donated heart valve transplant for children and young adults
This study is testing a new way to replace a damaged heart valve using a donated valve (allograft) that may last longer and work better for children and young adults. It may be a good option if you need a new valve and have few other choices.
Boston, MassachusettsAges 4 weeks–50 years - NCT03142152Recruiting
Mitral valve implant for heart failure with leaky mitral valve
This trial tests whether a device called the Carillon Mitral Contour System can help people with heart failure caused by a mild-to-moderate leaky mitral valve. You’d be compared against a control group, and the goal is to improve heart failure symptoms and outcomes.
Boston, MassachusettsAges 18 years+ - NCT05932615Enrolling by invitation
Testing a new transcatheter valve for aortic valve narrowing
This trial studies how safe and effective the NAVITOR valve is for treating narrowed aortic valves placed through a catheter (no open-heart surgery). It may be an option if you’re at intermediate-to-low surgical risk and meet heart ultrasound/CT measurements.
Worcester, MassachusettsAges 18 years+ - NCT04153292Recruiting
Testing a valve procedure for severe mitral regurgitation
This trial studies a minimally invasive mitral valve repair/replacement approach for people with severe mitral regurgitation (leaky mitral valve) who are not good candidates for standard surgery or catheter options. It may help improve symptoms by treating the leaky valve when other treatments aren’t suitable.
Boston, MassachusettsAges 18 years+ - NCT06455787Recruiting
J-Valve study for leaky aortic valve patients
This study tests a new, less invasive device called J-Valve for people with severe aortic regurgitation (a leaky aortic valve). It is placed through a tube in the leg artery, avoiding open-heart surgery, and may help those who are at high risk for surgery.
Boston, MassachusettsAges 18 years+ - NCT06137807Recruiting
TricValve for severe tricuspid regurgitation
This trial is testing a new device called the TricValve to treat severe tricuspid regurgitation (a leaky heart valve on the right side). It is for people who still have symptoms despite taking heart failure medications.
Burlington, MassachusettsAges 18 years+ - NCT04097145Recruiting
Heart valve repair for severe leaking tricuspid valve
This trial tests a catheter-based procedure (done through the blood vessels) to repair a severely leaky tricuspid valve. It may help people with symptoms or past hospitalizations from tricuspid valve leakage who are higher-risk for standard surgery.
Boston, MassachusettsAges 18 years+ - NCT06027788Recruiting
Embolic protection during heart valve surgery
This trial tests a device that may help protect your brain from small particles during heart valve surgery. It is for people 60 and older having certain types of valve replacement or repair.
Boston, MassachusettsAges 60 years+ - NCT04634240Recruiting
Staged heart bypass plus TAVR versus TAVR alone
This study compares doing a staged coronary bypass (revascularization) along with a valve procedure (TAVR) versus doing TAVR and medical treatment alone. It aims to see which approach better helps people with both aortic valve narrowing and coronary artery disease.
Boston, MassachusettsAges Any age
Mitral Valve Disease trials by city in Massachusetts
Where these studies are running in Massachusetts
Institutions with a site for the recruiting mitral valve disease studies listed above.
- Massachusetts General Hospital · 10 studies
- Brigham and Women's Hospital · 5 studies
- Beth Israel Deaconess Medical Center · 2 studies
- Boston Children's Hospital
- Lahey Hospital and Medical Center
- St. Elizabeth's Medical Center
- Tufts Medical Center
- University of Massachusetts Chan Medical School
What taking part in a mitral valve disease study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Mitral Valve Disease trials in other states
Common questions
- Are there mitral valve disease clinical trials in Massachusetts?
- Yes. We're currently tracking 13 recruiting mitral valve disease studies with a site in Massachusetts, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a mitral valve disease study in Massachusetts?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Massachusetts to take part?
- Not necessarily. These studies have a site in Massachusetts, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a mitral valve disease trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New mitral valve disease studies open in Massachusetts regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.