Donated heart valve transplant for children and young adults
Part of Heart & circulation clinical trials.
This study is testing a new way to replace a damaged heart valve using a donated valve (allograft) that may last longer and work better for children and young adults. It may be a good option if you need a new valve and have few other choices.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You need a new heart valve (aortic, pulmonary, mitral, or tricuspid).
- You are between 30 days old and 50 years old, with a focus on children and young adults who are still growing.
- You have few other options for a valve replacement, such as if your body might reject a regular artificial valve.
- You and your family can travel to Boston Children's Hospital within 48 hours if a valve is available.
- You are willing to have follow-up care at Boston Children's Hospital for at least 5 years.
- You do not have serious health problems like active infections, organ failure, or a recent history of cancer.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how well a new valve works when placed inside a previous mitral or tricuspid valve repair or replacement. It may help people who need another procedure on these heart valves.
This study tests a new type of replacement valve for children who need a new pulmonary valve (the valve between the heart and lungs). Researchers want to see if the valve works safely and well in real-world use.
This study tests an early, first-use version of a new pulmonary valve device for children whose own valve is not working well. It may help improve blood flow from the heart to the lungs and aims to learn how safe and effective the valve is over time.
This trial studies a surgery approach to help fix a narrowed or leaking aortic valve in children. It aims to see how well the reconstructed valve works and how it affects the child’s heart function over time.
This study tests a biological (tissue) heart valve replacement system designed to be easier to change later. It may help people who need valve surgery because their valve is narrowed or damaged.
This study tests whether a new type of heart valve made from your own tissue (an “autologous” valve) can be placed through a catheter safely in adults with leaking and pressure-related problems in the lung heart valve area. If it works well, it could offer a safer option for people who need treatment for pulmonary valve problems.
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