Clinical trials
Molar Incisor Hypomineralization clinical trials
Below are recruiting molar incisor hypomineralization clinical trials, each written for real people, not researchers. We’re tracking 11 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07504614Enrolling by invitation
Comparing two types of tooth sealants for kids with MIH
This study tests whether a new pre-etched bioactive sealant works better than a standard resin-based one to protect permanent molars affected by molar incisor hypomineralization (MIH), a condition that makes teeth softer and more prone to cavities. It aims to find a more effective way to prevent decay in these vulnerable teeth.
IrbidAges 6–12 - NCT05806398Recruiting
Sealant test for molars with enamel defects in children
This study tests whether a glass ionomer sealant can protect molars with molar-incisor hypomineralization (MIH), a type of enamel weakness, by sealing the biting surface. It may help reduce damage in affected teeth when children still have healthy surfaces that can be sealed.
TriesteAges 6–10 - NCT05964387Recruiting
Silver fluoride treatment and local numbing for tooth cavities
This study tests whether applying silver diamine fluoride (a cavity-stopping liquid) changes how well local numbing works during dental treatment for certain tooth defects. It may help determine the safest and most comfortable way to treat weak, cavity-prone molars in children.
Ann Arbor, MichiganAges 6–11 - NCT06641011Recruiting
Sealing molars with enamel spots: rinsing vs blotting
This study tests whether rinsing off or blotting dry a special silver fluoride liquid before placing a tooth sealant helps the sealant last longer on molars affected by a common condition called molar-incisor hypomineralization. The goal is to find the best way to protect these teeth from cavities.
AnkaraAges 6–14 - NCT06801561Recruiting
Sealants and Laser to Prevent Cavities in MIH-Affected Molars
This trial tests whether a dental sealant or a special laser treatment can prevent cavities and breakdown in first permanent molars affected by MIH (a condition that makes enamel weak). Eligible children have a molar with MIH that hasn't yet broken down and has only minor cavities.
AlexandriaAges 6–9 - NCT07352813Recruiting
Comparing numbing methods for kids with MIH teeth
This study tests two ways to numb teeth—in the bone or in the gum—to see which works better for children with weak enamel on their back teeth and front teeth. It may help find a pain-free way to treat these teeth.
AnkaraAges 6–12 - NCT07389148Recruiting
Saliva stress test for children with tooth spots
This study measures stress hormone levels in saliva of children with a tooth condition called MIH (chalky white or yellow spots on teeth) compared to healthy children. It aims to see if MIH is linked to higher stress.
Ankara, AnkaraAges 8–12 - NCT07436039Recruiting
Toothpaste for sensitivity and color improvement in MIH
This study tests a new toothpaste containing nano-hydroxyapatite, a substance that mimics natural enamel, to see if it can help reduce sensitivity and improve the color of teeth affected by Molar-Incisor Hypomineralization (MIH)—a condition where first molars and sometimes front teeth have white, yellow, or brown spots. It is for children aged 6 to 12 who have these spots on at least one permanent molar or baby molar.
JeddahAges 6–12 - NCT06396988Enrolling by invitation
Novamin for weak enamel in children's teeth
This study tests a special toothpaste ingredient (Novamin) that may help repair weak enamel on permanent back teeth and front teeth in children and teens. The treatment is applied by a dentist and may strengthen the teeth and reduce sensitivity.
Pavia, LombardyAges 7–14 - NCT04704089Recruiting
Dental enamel defect study using tooth photos and measurements
This study compares different types of enamel problems by taking detailed pictures of your front teeth. It may help researchers better tell these enamel conditions apart and improve future diagnosis and care.
ParisAges 8–55 - NCT06776471Recruiting
Sealant study for children with weak enamel
This study compares two types of dental sealants applied to the first permanent molars of children aged 6-12 who have a condition called molar incisor hypomineralization (MIH), which means their back teeth have soft or chalky spots. The goal is to see which sealant works better at protecting these teeth from cavities.
AnkaraAges 6–12
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Common questions
- Are there clinical trials for molar incisor hypomineralization?
- Yes. Clin2 currently lists 11 recruiting molar incisor hypomineralization studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a molar incisor hypomineralization trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a molar incisor hypomineralization trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.